Endocrine System Overview Quiz

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Questions and Answers

What clinical manifestations are associated with hyperthyroidism?

  • Progressive weight loss and hyperactivity
  • Hair loss and dry skin
  • Hypertension and excessive sweating
  • Drowsiness and confusion (correct)

Which mnemonic can help remember the clinical manifestations of hyperthyroidism?

  • Lungs, heart, brain, and organs
  • Headaches, fevers, shivers, and tremors
  • Moans, groans, stones, and bones (correct)
  • Sleep, eat, walk, and talk

What effect does hyperthyroidism have on serum calcium and phosphate levels?

  • Increases serum calcium and decreases phosphate (correct)
  • Increases both serum calcium and phosphate
  • No effect on serum calcium or phosphate
  • Decreases serum calcium and increases phosphate

What potential complication can arise from increased serum calcium levels?

<p>Kidney stones (A)</p> Signup and view all the answers

Which of the following is NOT a treatment for hyperthyroidism?

<p>Increased calcium supplementation (D)</p> Signup and view all the answers

What is a common symptom of bone demineralization in hyperthyroidism?

<p>Proximal muscle weakness (D)</p> Signup and view all the answers

What does the term 'osteopenia' refer to in the context of hyperthyroidism?

<p>Lower than normal bone mineral density (C)</p> Signup and view all the answers

Which psychological symptoms are associated with hyperthyroidism?

<p>Depression and confusion (D)</p> Signup and view all the answers

What is a potential cause of chronic adrenal insufficiency?

<p>Infection (D)</p> Signup and view all the answers

Which symptom is most commonly associated with Cushing syndrome?

<p>Moon face appearance (C)</p> Signup and view all the answers

What treatment is recommended for acute adrenal insufficiency?

<p>Replacement therapy (B)</p> Signup and view all the answers

Which of the following is a sign of secondary adrenal insufficiency?

<p>Lack of ACTH stimulation (C)</p> Signup and view all the answers

What commonly used medication can lead to adrenal insufficiency?

<p>Phenytoin (B)</p> Signup and view all the answers

In Cushing syndrome, which of the following findings is NOT typical?

<p>Tendon calcification (B)</p> Signup and view all the answers

What is the primary hormone secreted by the pineal gland, and what does it regulate?

<p>Melatonin; regulates sleep–wake cycles (D)</p> Signup and view all the answers

Which symptom is exclusively associated with adrenal insufficiency rather than Cushing syndrome?

<p>Hypoglycemia (D)</p> Signup and view all the answers

What is a common treatment approach for patients with Cushing syndrome?

<p>Surgical excision of pituitary tumor (A)</p> Signup and view all the answers

Which of the following is a risk factor included in the diagnosis of metabolic syndrome?

<p>Fasting plasma glucose ≥ 100 mg/dL (B)</p> Signup and view all the answers

What is a characteristic of Type 1 Diabetes Mellitus?

<p>Requires insulin injections or pump for management (A)</p> Signup and view all the answers

What is a major risk factor for developing Cushing syndrome?

<p>Chronic stress or high cortisol levels (C)</p> Signup and view all the answers

Which factor is NOT associated with the etiology of adrenal insufficiency?

<p>Hypotensive episodes (A)</p> Signup and view all the answers

What primary lifestyle modification can reduce the risk of developing metabolic syndrome?

<p>Vigorous physical activity (C)</p> Signup and view all the answers

Which of the following describes a symptom associated with diabetic ketoacidosis (DKA)?

<p>Hyperventilation (D)</p> Signup and view all the answers

What contributes to the etiology of Type 1 Diabetes Mellitus?

<p>Viral infections and autoimmune responses (C)</p> Signup and view all the answers

Which condition is characterized by high triglycerides and low HDL cholesterol levels?

<p>Metabolic syndrome (D)</p> Signup and view all the answers

What is a possible complication of poorly managed Type 1 Diabetes Mellitus?

<p>Diabetic neuropathy (D)</p> Signup and view all the answers

Which abnormal blood pressure reading indicates a risk factor for metabolic syndrome?

<p>Systolic blood pressure ≥ 130 mmHg (A)</p> Signup and view all the answers

Which group has a higher prevalence of diabetes mellitus due to genetic and ethnic factors?

<p>Native American and Hispanic populations (D)</p> Signup and view all the answers

What role does the hypothalamus play in the endocrine system?

<p>Maintains body homeostasis and regulates the autonomic nervous system (C)</p> Signup and view all the answers

Which gland is referred to as the 'master' gland?

<p>Pituitary gland (A)</p> Signup and view all the answers

Which hormone is NOT secreted by the anterior pituitary gland?

<p>Oxytocin (A)</p> Signup and view all the answers

What function does calcitonin serve in the body?

<p>Affects calcium and phosphorus homeostasis (C)</p> Signup and view all the answers

Which of the following hormones is produced by the adrenal cortex?

<p>Aldosterone (D)</p> Signup and view all the answers

What is the role of glucagon in the body?

<p>Stimulates glucose production by the liver (A)</p> Signup and view all the answers

How does cortisol function in the body?

<p>Promotes gluconeogenesis and regulates carbohydrate metabolism (D)</p> Signup and view all the answers

Which hormone released from the pancreas primarily lowers blood glucose levels?

<p>Insulin (B)</p> Signup and view all the answers

What effect does aldosterone have on the body?

<p>Regulates fluid and electrolyte balance (C)</p> Signup and view all the answers

Which hormone is primarily responsible for male sexual characteristics?

<p>Testosterone (D)</p> Signup and view all the answers

What is the primary function of the islets of Langerhans in the pancreas?

<p>Secrete hormones that regulate blood sugar levels (D)</p> Signup and view all the answers

How do thyroid hormones (T3 and T4) affect the body?

<p>Control metabolic rate and protein synthesis (B)</p> Signup and view all the answers

What is the role of oxytocin in the body?

<p>Stimulates contractions during childbirth (A)</p> Signup and view all the answers

Which gland is responsible for converting vitamin D into its active form?

<p>Kidneys (A)</p> Signup and view all the answers

Flashcards

Melatonin

A hormone produced by the pineal gland that regulates sleep-wake cycles.

Thymosin

A hormone produced by the thymus that helps in the development of T-cells for the immune system.

Metabolic Syndrome (Syndrome X)

A collection of risk factors that increase the chance of heart disease, stroke, and diabetes.

Insulin Resistance

A sign of metabolic syndrome, it's a condition where your body can't use insulin properly.

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Diabetes Mellitus (DM)

A chronic disorder affecting carbohydrate, fat, and protein metabolism due to insufficient insulin action.

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Type 1 DM

Type of DM where the body doesn't produce enough insulin. 5-10% of cases.

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Type 2 DM

Type of DM where the body resists the effects of insulin. 90-95% of cases.

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Kussmaul breathing

A sign of DKA characterized by rapid, deep breathing.

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Ketones

Ketones are produced when the body breaks down fat for energy.

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Ketonuria

A condition in which ketone bodies are present in the urine.

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Adrenal Insufficiency

A condition where the adrenal glands produce insufficient amounts of cortisol and aldosterone.

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Addison's Disease

An autoimmune condition that affects the adrenal glands, leading to decreased cortisol and aldosterone production.

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Secondary Adrenal Insufficiency

A condition where the pituitary gland doesn't produce enough ACTH, resulting in decreased cortisol production.

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Cushing Syndrome

A condition characterized by excessive cortisol production by the adrenal glands.

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Moon Face

A symptom of Cushing Syndrome characterized by a round face.

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Buffalo Hump

A symptom of Cushing Syndrome characterized by a fatty deposit at the base of the neck.

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Truncal Obesity

A symptom of Cushing Syndrome characterized by excessive fat accumulation around the abdomen.

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Osteoporosis

A symptom of Cushing Syndrome characterized by weakened and thinned bones.

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Hypertension (HTN)

A symptom of Cushing Syndrome characterized by increased blood pressure.

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Kyphosis

A symptom of Cushing Syndrome characterized by a curved upper back.

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Endocrine System

A group of glands that release hormones to regulate body functions.

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Hyperparathyroidism

A condition where the parathyroid gland produces excessive parathyroid hormone (PTH), leading to disruptions in calcium, phosphate, and bone metabolism.

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Hormones

Chemical messengers that regulate various body functions.

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Hypercalcemia

Increased levels of calcium in the blood serum due to hyperparathyroidism.

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Hypothalamus

The brain's control center for the endocrine system, regulating appetite, temperature, and more.

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Hypophosphatemia

Decreased levels of phosphate in the blood serum due to hyperparathyroidism.

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Osteopenia

Weakening of bones caused by the excessive removal of calcium from bones in hyperparathyroidism.

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Pituitary Gland

The "master" gland that regulates other glands in the body.

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Anterior Pituitary Gland

The front part of the pituitary gland that releases hormones like growth hormone and ACTH.

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Kidney Stones

Kidney stones or renal calculi can form as a result of high calcium levels in the blood due to hyperparathyroidism.

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Posterior Pituitary Gland

The back part of the pituitary gland that releases hormones like antidiuretic hormone (ADH) and oxytocin.

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Clinical Manifestations of Hyperparathyroidism

A condition that occurs in hyperparathyroidism, characterized by fatigue, drowsiness, confusion, poor memory, slowed mentation, myalgias, depression, stocking-and-glove sensory loss, hyperactive deep tendon reflexes (DTRs), osteopenia, gout or pseudogout, proximal muscle weakness, arthralgia, myalgia, nausea, vomiting, constipation, peptic ulcers, pancreatitis, kidney stones.

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Thyroid Gland

A gland in the neck that produces hormones that regulate metabolism.

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Primary Adrenal Insufficiency

A condition where the adrenal cortex is not functioning properly, resulting in low levels of cortisol and aldosterone.

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Thyroxine (T4) and Triiodothyronine (T3)

Hormones produced by the thyroid gland that regulate metabolism and protein synthesis.

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Parathyroid Glands

Small glands near the thyroid that regulate calcium and phosphate levels.

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Adrenal Gland

A gland located near the kidneys that produces hormones like cortisol and aldosterone.

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Adrenal Cortex

The outer layer of the adrenal gland that produces corticosteroids which regulate sodium, potassium, and carbohydrate metabolism.

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Adrenal Medulla

The inner layer of the adrenal gland that produces epinephrine and norepinephrine, involved in the "fight-or-flight" response.

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Islets of Langerhans

Clusters of cells in the pancreas that produce hormones like insulin, glucagon, and amylin.

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Insulin

Hormone produced by the pancreas that lowers blood glucose levels.

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Glucagon

Hormone produced by the pancreas that raises blood glucose levels.

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Study Notes

Endocrine System Overview

  • The endocrine system is a network of glands that secrete hormones to regulate body functions
  • The system works smoothly when functioning properly
  • The hypothalamus, pituitary gland, and nervous system form a central network that controls other glands

Hormonal Regulation

  • Hormones are chemical messengers that relay information to cells and organs to regulate body functions
  • The endocrine system regulates body homeostasis

Hypothalamus

  • Regulates the autonomic nervous system (ANS)
  • Controls various bodily functions including temperature, thirst, blood pressure, and sleep
  • Controls pituitary hormone release

Corticotropin-releasing Hormone (CRH)

  • A hormone released by the hypothalamus to trigger the release of cortisol from the adrenal glands
  • Part of the hypothalamus "TALE" (temperature, appetite, libido, emotion) mnemonic

Thyrotropin-releasing Hormone (TRH)

  • A hormone released by the hypothalamus to trigger the release thyroid-stimulating hormone (TSH) from the pituitary gland

Growth Hormone-releasing Hormone (GHRH)

  • A hormone released by the hypothalamus to trigger the release of growth hormone from the anterior pituitary gland

Somatostatin

  • A hormone released by the hypothalamus that inhibits the release of growth hormone

Pituitary Gland

  • Considered the "master gland"
  • Located near the hypothalamus
  • Regulates other glands
  • Anterior pituitary releases hormones like growth hormone (GH), adrenocorticotropic hormone (ACTH), follicle-stimulating hormone (FSH), prolactin, luteinizing hormone (LH), thyroid-stimulating hormone (TSH)
  • Posterior pituitary releases antidiuretic hormone (ADH) and oxytocin

Thyroid Gland

  • Follicular cells secrete thyroxine (T4) and triiodothyronine (T3) to regulate metabolism and protein synthesis
  • C cells secrete calcitonin to manage calcium and phosphorus homeostasis

Parathyroid Glands

  • Release parathyroid hormone (PTH)
  • Regulates calcium and phosphate homeostasis and bone calcification in blood

Adrenal Glands

  • Adrenal cortex releases corticosteroids like aldosterone to regulate potassium and sodium levels and maintain fluid balance
  • Examples of corticosteroids include cortisol.

Other Glands (from the figures)

  • Pineal gland produces melatonin
  • Thymus produces thymosin, supporting immune system T-cell development
  • Pancreas produces insulin, glucagon, and amylin, regulating blood sugar
  • Ovaries produce estrogen and progesterone, regulating female reproductive system and pregnancy
  • Testes produce testosterone, regulating male characteristics
  • Kidneys convert vitamin D into its active form
  • Adrenal medulla releases epinephrine and norepinephrine, aiding the fight-or-flight response

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