Endocrine System Overview Quiz

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Questions and Answers

What is the primary function of the endocrine system?

  • To detoxify substances in the body
  • To produce hormones that regulate metabolic activities (correct)
  • To facilitate respiratory processes
  • To control voluntary movements

Exocrine glands produce hormones.

False (B)

What are hormones?

Chemical messengers that act upon target tissue.

The main organs of the endocrine system include the pituitary, thyroid, and ______.

<p>adrenal</p> Signup and view all the answers

Match the following hormones with their characteristics:

<p>Water-soluble hormones = Attach to cell surface receptors Lipid-soluble hormones = Pass through the plasma membrane Amino acid hormones = Use second messenger systems Steroid hormones = Derived from cholesterol</p> Signup and view all the answers

How do water-soluble hormones typically exert their effects?

<p>By binding to cell surface receptors (A)</p> Signup and view all the answers

Lipid-soluble hormones are impermeable to the plasma membrane.

<p>False (B)</p> Signup and view all the answers

What is a target tissue?

<p>Tissue that contains receptors activated by specific hormones.</p> Signup and view all the answers

Which stimulus is the most rare and quickest in hormone release?

<p>Neural Stimulus (D)</p> Signup and view all the answers

The hypothalamus is responsible for controlling blood calcium levels through hormonal feedback systems.

<p>False (B)</p> Signup and view all the answers

What type of hormones are produced by the anterior pituitary gland?

<p>GH, TSH, ACTH, FSH, LH, PRL</p> Signup and view all the answers

Hormones are removed from the blood by _____, _____, and _____.

<p>degrading enzymes, kidneys, liver</p> Signup and view all the answers

Match the following hormones with their respective functions:

<p>GH = Stimulates growth of body tissues TSH = Stimulates production of thyroid hormone ACTH = Stimulates cortisol production in adrenal cortex PRL = Stimulates milk production in breasts</p> Signup and view all the answers

What is the primary function of Antidiuretic Hormone (ADH)?

<p>Decreases urine production and increases water retention (C)</p> Signup and view all the answers

Hypersecretion of growth hormone can cause gigantism.

<p>True (A)</p> Signup and view all the answers

What role does the infundibulum serve in the endocrine system?

<p>It connects the hypothalamus to the pituitary gland.</p> Signup and view all the answers

The primary effect of the action of epinephrine is to support the _____ response.

<p>fight or flight</p> Signup and view all the answers

Which of the following hormones stimulates the release of egg during the menstrual cycle?

<p>LH (D)</p> Signup and view all the answers

What is the primary function of calcitonin?

<p>Lower blood calcium levels (A)</p> Signup and view all the answers

Thyroxine (T4) helps to increase metabolic activity in most tissue cells.

<p>True (A)</p> Signup and view all the answers

What hormone is secreted by the adrenal cortex and acts as an anti-inflammatory?

<p>Cortisol</p> Signup and view all the answers

The hormone glucagon is produced by the ______ cells of the pancreas.

<p>alpha</p> Signup and view all the answers

Match the following hormones with their functions:

<p>Calcitonin = Lowers calcium levels Aldosterone = Regulates sodium and potassium Melatonin = Regulates day/night cycle Testosterone = Maturation of gonads</p> Signup and view all the answers

What is the main consequence of hyperparathyroidism?

<p>Increased calcium levels (A)</p> Signup and view all the answers

Hypoparathyroidism leads to high blood calcium levels.

<p>False (B)</p> Signup and view all the answers

What does the adrenal cortex glucocorticoids primarily stimulate?

<p>Gluconeogenesis</p> Signup and view all the answers

During darker environments, the pineal gland produces more ______.

<p>melatonin</p> Signup and view all the answers

Which type of diabetes is characterized by autoimmune destruction of beta cells?

<p>Type 1 Diabetes (C)</p> Signup and view all the answers

Which condition is associated with the hypersecretion of aldosterone?

<p>Aldosteronism (C)</p> Signup and view all the answers

Type 2 diabetes is primarily caused by an autoimmune response.

<p>False (B)</p> Signup and view all the answers

What is the primary hormone produced by alpha cells?

<p>Glucagon</p> Signup and view all the answers

Excessive thirst due to high urine output is known as ____________.

<p>Polydipsia</p> Signup and view all the answers

What hormone is primarily responsible for stimulating muscle growth during puberty?

<p>Testosterone (C)</p> Signup and view all the answers

A humoral stimulus involves direct neural signals to trigger hormone release.

<p>False (B)</p> Signup and view all the answers

What is glycosuria?

<p>Excess glucose in urine</p> Signup and view all the answers

Stress hormones like norepinephrine and epinephrine are produced by the ____________.

<p>adrenal glands</p> Signup and view all the answers

What effect do environmental pollutants have on hormone function?

<p>Disrupt hormone function (D)</p> Signup and view all the answers

Flashcards

Humoral Stimulus (CHEMICAL)

The release of hormones is triggered by changes in blood levels of certain chemicals, like calcium.

Neural Stimulus

Hormone release is initiated by the nervous system, typically through the autonomic nervous system (ANS).

Hormonal Stimulus

The most common stimulus for hormone release, where one endocrine gland is stimulated by a hormone from another gland.

Nervous System Modulation

The hypothalamus and sympathetic nervous system can override insulin release under severe stress, leading to increased blood glucose levels.

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How are hormones removed from the blood?

The process of removing hormones from the blood involves breakdown by enzymes, filtration by the kidneys, and processing by the liver.

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How quickly do hormones act?

Hormones can have immediate effects or require activation within target cells.

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How long do hormones last?

The duration of hormone effects can range from seconds to hours. Effects may decrease as blood levels drop, but some persist at low levels.

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The Hypothalamus

A gland located in the brain, connected to the pituitary gland by the infundibulum.

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Hypophysis (Pituitary gland)

The pituitary gland, also known as the hypophysis, is a master gland that controls other glands.

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Anterior Pituitary

A part of the pituitary gland that produces growth hormone (GH), thyroid-stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin (PRL).

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Calcitonin

A hormone secreted by the thyroid gland that lowers blood calcium levels by stimulating calcium deposition in bones.

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Parathyroid Hormone (PTH)

A hormone secreted by the parathyroid glands that increases blood calcium levels by stimulating calcium release from bones and absorption in the intestines.

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Thyroxine (T4)

The primary hormone produced by the thyroid gland, responsible for regulating metabolism.

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Aldosterone

A critical hormone produced by the adrenal cortex, responsible for regulating sodium and potassium balance.

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Cortisol

A hormone produced by the adrenal cortex, playing a crucial role in stress response and glucose regulation.

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Melatonin

A hormone primarily secreted by the pineal gland, responsible for regulating the sleep-wake cycle.

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Glucagon

A hormone secreted by the pancreas that increases blood glucose levels by stimulating the breakdown of glycogen in the liver.

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Hyperparathyroidism

A condition caused by hypersecretion of parathyroid hormone, characterized by increased blood calcium levels and bone breakdown.

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Hypoparathyroidism

A condition caused by hyposecretion of parathyroid hormone, characterized by decreased blood calcium levels and muscle spasms.

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Cushing's Disease

A condition caused by hypersecretion of cortisol, characterized by weight gain, muscle weakness, and high blood sugar.

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Insulin

Insulin is a hormone produced by beta cells in the pancreas. It helps regulate blood glucose levels by promoting glucose uptake by cells and stimulating glycogen synthesis in the liver. Insulin is released in response to high blood glucose levels.

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Type 1 Diabetes

Type 1 diabetes is an autoimmune disease where the body's immune system destroys beta cells in the pancreas. Without beta cells, the pancreas cannot produce insulin, leading to high blood glucose levels.

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Type 2 Diabetes

Type 2 diabetes is a condition where the body develops resistance to insulin. The pancreas may still produce insulin, but the cells don't respond normally. Over time, the pancreas may not be able to produce enough insulin to meet the body's needs.

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Glycosuria

Glycosuria is a condition where excess glucose in the blood is spilled into the urine. This occurs when the kidneys cannot reabsorb all the filtered glucose. Glycosuria is a common symptom of diabetes.

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Polyuria

Polyuria is excessive urination. This is a common symptom of diabetes because high blood glucose acts as an osmotic diuretic, pulling water into the urine.

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Polydipsia

Polydipsia is excessive thirst. In diabetes, this is often a response to the water loss caused by Polyuria.

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Polyphagia

Polyphagia is excessive hunger and food consumption. This can occur in diabetes because cells cannot take up glucose and are 'starving.' The body tries to compensate by eating more.

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Pineal Gland

The pineal gland is an endocrine gland located in the brain. It produces melatonin, a hormone that helps regulate sleep-wake cycles.

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Thymus Gland

The thymus gland is an endocrine gland located in the chest. It produces thymopoietin and thymosin, hormones that are essential for the development and maturation of T lymphocytes, which are important for immune function.

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Endocrine System

The body's second major control system that influences cell metabolism using hormones. Works alongside the nervous system to coordinate and integrate body functions.

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Endocrine Glands

Glands that release hormones directly into the bloodstream, without ducts.

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Hormones

Chemical messengers produced by endocrine glands, acting on target tissues.

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Target Tissue

Tissues that have receptors specifically designed to bind to a particular hormone and respond.

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Water Soluble Hormones

Hormones that can't pass through the plasma membrane (cell wall) directly, so they bind to receptors on the cell's outer surface, triggering a chain reaction inside the cell.

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Lipid-Soluble Hormones

Hormones that can pass through the plasma membrane and bind directly to receptors inside the cell, then directly activating genes.

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Second Messenger System

A mechanism used by water-soluble hormones to relay signals inside the cell, using a cascade of molecules.

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Direct Gene Activation

A method used by lipid-soluble hormones to directly affect genes inside the cell.

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Study Notes

Endocrine System Overview

  • The endocrine system is the body's second controlling system, influencing metabolic activities through hormones. It works with the nervous system to coordinate and integrate cellular activity.
  • Endocrine glands produce hormones directly into the bloodstream; they lack ducts. Exocrine glands produce non-hormonal substances (e.g., saliva, sweat) via ducts that lead to the external environment.

Hormones

  • Hormones are chemical messengers that act upon target tissues containing specific receptors. Most hormone action is regulated via negative feedback.
  • Hormones can affect cell function in various ways, like increasing protein production, influencing cell division, or altering cell function. Hormones may also stimulate other glands to release their own hormones.

Hormone Types and Action

  • Water-soluble hormones (most amino acid-based hormones except thyroid hormone) cannot directly enter cells; they bind to cell surface receptors, activating a second messenger system within the cell.
  • Lipid-soluble hormones (steroid and thyroid hormones) can pass through the cell membrane and bind to intracellular receptors, directly activating genes.

Hormone Secretion Regulation

  • Humoral stimuli: Hormone release is triggered by changes in blood levels of certain substances (e.g., blood calcium levels).
  • Neural stimuli: The nervous system directly triggers hormone release (e.g., fight-or-flight response).
  • Hormonal stimuli: Certain hormones stimulate the release of other hormones (e.g., hypothalamic hormones triggering anterior pituitary hormones).
  • Nervous system modulation: The nervous system can override hormonal control under extreme stress.

Hormone Removal and Action Time

  • Hormones are removed from the bloodstream by degradation enzymes, kidneys, and liver.
  • Hormone action times vary greatly, from immediate responses to several hours.
  • Hormone effects persist until blood levels decline.

Hypothalamus and Pituitary Gland

  • The hypothalamus regulates the pituitary gland (hypophysis) via the infundibulum.
  • The pituitary gland is often called the "master gland" due to its control over other endocrine glands.

Anterior Pituitary Hormones

  • Growth Hormone (GH): Stimulates somatic growth; hyposecretion leads to dwarfism, hypersecretion to gigantism.
  • Thyroid-stimulating hormone (TSH): Stimulates the thyroid gland, affecting metabolic rate.
  • Adrenocorticotropic hormone (ACTH): Stimulates the adrenal cortex to produce cortisol, impacting stress responses.
  • Follicle-stimulating hormone (FSH): Stimulates sperm and egg production.
  • Luteinizing hormone (LH): Stimulates sex hormone release and egg release.
  • Prolactin (PRL): Stimulates milk production in mammary glands.

Posterior Pituitary Hormones

  • Oxytocin: Stimulates uterine contractions and milk ejection, associated with bonding.
  • Antidiuretic hormone (ADH): Decreases urine output and increases water retention, impacting blood volume and pressure; inhibited by alcohol.

Thyroid Gland

  • The thyroid gland regulates metabolism.
  • Thyroxine (T4) and Triiodothyronine (T3): Increase metabolic activity; hyposecretion can cause cretinism or myxedema; hypersecretion causes Grave's disease.
  • Calcitonin: Lowers blood calcium levels.

Parathyroid Glands

  • Parathyroid Hormone (PTH): Raises blood calcium levels via actions on bones, kidneys, and intestines. Hyperparathyroidism leads to high calcium levels, while hypoparathyroidism causes low calcium levels (tetany).

Adrenal Glands

  • Adrenal Cortex (Aldosterone): Regulates salt and water balance. Hypersecretion causes aldosteronism, affecting blood pressure and electrolytes.
  • Adrenal Cortex (Glucocorticoids - Cortisol): Important in stress response, metabolism, and immune function. Hypersecretion causes Cushing's disease.
  • Adrenal Cortex (Gonadocorticoids): Contribute to sex hormone levels.

Pancreas

  • The pancreas has both exocrine and endocrine functions.
  • Insulin (beta cells): Lowers blood glucose levels; hyposecretion leads to diabetes mellitus (type 1 often autoimmune).
  • Glucagon (alpha cells): Raises blood glucose levels.
  • Diabetes Mellitus: A group of metabolic disorders relating to high blood glucose levels.

Pineal Gland

  • The pineal gland secretes melatonin, regulating the sleep-wake cycle.

Other Endocrine Glands

  • Thymus gland: Plays a role in immune function.
  • Gonads (testes and ovaries): Produce sex hormones (testosterone, estrogen, progesterone).
  • Placenta: Secretes hormones vital during pregnancy.
  • Adipose tissue: Secretes hormones that regulate appetite and energy expenditure.
  • Heart: Secretes ANP to regulate blood pressure.
  • Kidneys: Produce renin and erythropoietin.

Aging and Endocrine System

  • Endocrine function typically declines with age. Changes in hormone levels can affect metabolism, growth, and other physiological processes.

Environmental Pollutants

  • Environmental pollutants can disrupt hormone function, impacting various endocrine pathways.

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