Chapter 17 | Hypothalamic Regulation of Hormonal

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Questions and Answers

How is thirst affected by decreases in extracellular fluid (ECF) volume?

  • Increases thirst by decreasing renin secretion
  • Stimulates thirst through a pathway independent of increased plasma osmolality (correct)
  • Inhibits thirst by decreasing renin secretion
  • Has no effect on thirst

What is the role of angiotensin II in the hypothalamic regulation of thirst?

  • Stimulates the release of anti-thirst hormones
  • Has no impact on the thirst regulation process
  • Inhibits neural areas concerned with thirst
  • Acts on the subfornical organ to stimulate thirst-related neural areas (correct)

What stimulates renin secretion and leads to an increase in angiotensin II levels?

  • Increased blood pressure
  • Hypoventilation
  • Increased plasma osmolality
  • Hypovolemia (correct)

Which specialized receptor area in the diencephalon is stimulated by angiotensin II to affect thirst?

<p>Subfornical organ (B)</p> Signup and view all the answers

What is one factor that contributes to an increase in liquid intake during eating?

<p>Gastrointestinal hormone action on the hypothalamus (C)</p> Signup and view all the answers

What happens when the sensation of thirst is obtunded?

<p>Patients stop drinking adequate amounts of fluid (D)</p> Signup and view all the answers

What contributes to most cases of hypernatremia?

<p>Simple dehydration in patients with psychoses or hypothalamic disease (D)</p> Signup and view all the answers

Why does high protein intake lead to large amounts of water required to maintain hydration?

<p>Products of protein metabolism cause an osmotic diuresis (A)</p> Signup and view all the answers

What is the main function of vasopressin mentioned in the text?

<p>Promoting water retention by the kidney (B)</p> Signup and view all the answers

Where are vasopressin-secreting neurons found, according to the text?

<p>Hypothalamus (A)</p> Signup and view all the answers

What are the types of vasopressin receptors mentioned in the text?

<p>V1A, V1B, V2 (C)</p> Signup and view all the answers

What is the physiological consequence of vasopressin's action on the kidney according to the text?

<p>Decreased urine volume and concentration (D)</p> Signup and view all the answers

Which term is commonly used to refer to the chemical agents secreted by the hypothalamus into the portal hypophysial vessels?

<p>Hypophysiotropic hormones (B)</p> Signup and view all the answers

Which hormone is now generally known as gonadotropin-releasing hormone (GnRH)?

<p>Luteinizing hormone–releasing hormone (LHRH) (C)</p> Signup and view all the answers

What is the modern term used for Growth hormone–inhibiting hormone (GIH)?

<p>Somatostatin (D)</p> Signup and view all the answers

Which of the following polypeptides found in the hypothalamus stimulates prolactin secretion?

<p>VIP (D)</p> Signup and view all the answers

Where do most of the supraoptic fibers end in the hypothalamus?

<p>Posterior lobe (A)</p> Signup and view all the answers

From where do sympathetic nerve fibers reach the anterior lobe of the pituitary gland?

<p>Capsule (C)</p> Signup and view all the answers

What forms a direct vascular link between the hypothalamus and the anterior pituitary?

<p>Portal hypophysial vessels (D)</p> Signup and view all the answers

What is a characteristic of the circulatory system connecting the hypothalamus and anterior pituitary, as described in the text?

<p>Bypasses the heart (D)</p> Signup and view all the answers

What is the primary role of the hypothalamus in regulating the endocrine system?

<p>Regulating emotional behavior (B)</p> Signup and view all the answers

How does the posterior pituitary gland connect to the hypothalamus?

<p>Through neural connections (B)</p> Signup and view all the answers

In embryological terms, from where does the posterior pituitary gland originate?

<p>Wall of the third ventricle (B)</p> Signup and view all the answers

What is the composition of the posterior pituitary?

<p>Mainly consists of axon endings from specific nuclei (D)</p> Signup and view all the answers

What is the main effect of vasopressin on the kidney, as described in the text?

<p>Increasing the permeability of the collecting ducts (A)</p> Signup and view all the answers

Where else in the body, besides the hypothalamus, are vasopressin and oxytocin found according to the text?

<p>Adrenal cortex (A)</p> Signup and view all the answers

Which receptors are involved in the actions of vasopressin, as mentioned in the text?

<p>V1A, V1B, V2 (C)</p> Signup and view all the answers

What is one of the roles of vasopressin-secreting neurons found in the suprachiasmatic nuclei?

<p>Controlling cardiovascular functions (A)</p> Signup and view all the answers

What is the physiologic role of hCRH-RII according to the text?

<p>It is involved in receptor internalization in corticotropes (A)</p> Signup and view all the answers

Which type of hormones do NOT have known binding proteins according to the text?

<p>Vasopressin (D)</p> Signup and view all the answers

In most mammals, which hormones are secreted by the posterior pituitary gland?

<p>Vasopressin and oxytocin (C)</p> Signup and view all the answers

What is the main physiological consequence of oxytocin's action according to the text?

<p>Promoting lactation and uterine contractions (D)</p> Signup and view all the answers

What is the physiologic role of CRH-binding protein in the peripheral circulation?

<p>Inactivating CRH (D)</p> Signup and view all the answers

In most mammals, what are the hormones secreted by the posterior pituitary gland?

<p>Vasopressin and oxytocin (B)</p> Signup and view all the answers

Where is hCRH-RII primarily found?

<p>Many parts of the brain (B)</p> Signup and view all the answers

What is the main physiological action of vasopressin?

<p>Increasing urine concentration (D)</p> Signup and view all the answers

Which part of the body does oxytocin primarily act on?

<p>Breasts and uterus (A)</p> Signup and view all the answers

The hypothalamus regulates emotional and instinctual behavior independently of the limbic system.

<p>False (B)</p> Signup and view all the answers

The posterior pituitary arises from the floor of the fourth ventricle.

<p>False (B)</p> Signup and view all the answers

Vasopressin and oxytocin primarily act on the adrenal glands.

<p>False (B)</p> Signup and view all the answers

The anterior pituitary is directly connected to the hypothalamus via neural connections.

<p>False (B)</p> Signup and view all the answers

Hemorrhage can lead to decreased drinking even if plasma osmolality remains unchanged.

<p>False (B)</p> Signup and view all the answers

Renin secretion is decreased by hypovolemia, resulting in a decrease in circulating angiotensin II.

<p>False (B)</p> Signup and view all the answers

The subfornical organ is not involved in the stimulation of neural areas related to thirst.

<p>False (B)</p> Signup and view all the answers

The organum vasculosum of the lamina terminalis (OVLT) is not affected by angiotensin II according to some evidences.

<p>False (B)</p> Signup and view all the answers

Thirst response to hypovolemia is completely blocked by drugs that block the action of angiotensin II.

<p>False (B)</p> Signup and view all the answers

High protein intake causes a decrease in the amounts of water required to maintain hydration.

<p>False (B)</p> Signup and view all the answers

Patients with psychoses or hypothalamic disease always increase their water intake when their thirst mechanism is stimulated.

<p>False (B)</p> Signup and view all the answers

An increase in plasma osmolality occurs as food is absorbed, contributing to a learned response of increased liquid intake during eating.

<p>True (A)</p> Signup and view all the answers

Hypophysiotropic hormones are commonly known as releasing and inhibiting factors.

<p>False (B)</p> Signup and view all the answers

Prolactin-releasing hormone (PRH) has been confirmed to exist according to the text.

<p>False (B)</p> Signup and view all the answers

VIP is one of the hypothalamic polypeptides that stimulate prolactin secretion.

<p>True (A)</p> Signup and view all the answers

Luteinizing hormone–releasing hormone (LHRH) is generally known as corticotropin-releasing hormone (CRH).

<p>False (B)</p> Signup and view all the answers

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