Endocrine System Anatomy Quiz
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Questions and Answers

What are the Herring bodies primarily known for?

  • Transporting hormones to the bloodstream
  • Storing neurosecretory material (correct)
  • Maintaining osmotic balance
  • Connecting the pituitary gland to the hypothalamus

Pituicytes are endocrine cells that release hormones into the bloodstream.

False (B)

What hormones are associated with the neurosecretory bodies in the neurohypophysis?

Oxytocin and ADH

The axons from the supraoptic and __________ nuclei are mainly concerned with oxytocin secretion.

<p>paraventricular</p> Signup and view all the answers

What triggers the release of ADH from the neurosecretory bodies?

<p>Increased blood tonicity (B)</p> Signup and view all the answers

Match the following components of the pituitary gland with their functions:

<p>ADH = Increases water reabsorption in renal collecting ducts Pituicytes = Support neurosecretory fibers Herring bodies = Store neurosecretory material Inferior hypophyseal arteries = Supply blood to the neurohypophysis</p> Signup and view all the answers

The blood supply of the pituitary gland comes entirely from the internal jugular vein.

<p>False (B)</p> Signup and view all the answers

What is the primary role of the superior hypophyseal arteries?

<p>Supply the median eminence and the infundibular stalk</p> Signup and view all the answers

Which gland is NOT part of the endocrine system?

<p>Liver (D)</p> Signup and view all the answers

The endocrine system includes both ductless glands and isolated cells within certain organs.

<p>True (A)</p> Signup and view all the answers

What do hormone-producing cells in the adrenal cortex synthesize?

<p>Steroid hormones</p> Signup and view all the answers

The ______ is a ductless gland located at the base of the skull.

<p>pituitary gland</p> Signup and view all the answers

Match the following components of the pituitary gland with their descriptions:

<p>Pars Distalis = Main hormone-producing area of the anterior lobe Pars Tuberalis = Wraps around the infundibulum stalk Pars Intermedia = Thin zone adjacent to pars nervosa Pars Nervosa = Part of the posterior lobe of the pituitary</p> Signup and view all the answers

What type of hormones are synthesized by rough endoplasmic reticulum?

<p>Peptides (C)</p> Signup and view all the answers

Amine hormones are synthesized from cholesterol.

<p>False (B)</p> Signup and view all the answers

What is the primary function of the endocrine system?

<p>Regulate body functions through hormones</p> Signup and view all the answers

What is the primary role of the hypothalamic-hypophyseal portal system?

<p>To carry neuropeptides from the hypothalamus to the adenohypophysis (A)</p> Signup and view all the answers

Antidiuretic hormone (ADH) is synthesized in the paraventricular nuclei.

<p>False (B)</p> Signup and view all the answers

What are the two peptide hormones synthesized by hypothalamic neurons mentioned?

<p>Antidiuretic hormone (ADH) and oxytocin</p> Signup and view all the answers

The pineal gland is also known as the ______.

<p>epiphysis cerebri</p> Signup and view all the answers

Which cells produce growth hormone?

<p>Somatotrophs (A)</p> Signup and view all the answers

Match the following hormones with their hypothalamic nuclei:

<p>Antidiuretic hormone (ADH) = Supraoptic nucleus Oxytocin = Paraventricular nucleus</p> Signup and view all the answers

All hypothalamic hormones that affect the anterior pituitary are releasing hormones.

<p>False (B)</p> Signup and view all the answers

What shape is the pineal gland?

<p>Pine cone-shaped</p> Signup and view all the answers

What type of cells are primarily found in the pars intermedia?

<p>Basophils and chromophobes (D)</p> Signup and view all the answers

The pars distalis accounts for 50% of the mass of the pituitary gland.

<p>False (B)</p> Signup and view all the answers

What is the primary function of melanocyte-stimulating hormone (MSH)?

<p>Increases melanocyte activity</p> Signup and view all the answers

The neurohypophysis is also known as the ______.

<p>pars nervosa</p> Signup and view all the answers

Match the following types of cells with their corresponding hormones:

<p>Somatotrophs = Growth Hormone (GH) Thyrotrophs = Thyroid Stimulating Hormone (TSH) Gonadotrophs = Follicle Stimulating Hormone (FSH) Corticotrophs = Adrenocorticotrophic Hormone (ACTH)</p> Signup and view all the answers

What is the primary function of the pineal gland?

<p>Producing melatonin (D)</p> Signup and view all the answers

Which component consists of the unmyelinated axons from magnocellular neurosecretory cells?

<p>Pars nervosa (B)</p> Signup and view all the answers

Chromophobes take up histological stains.

<p>False (B)</p> Signup and view all the answers

The presence of corpora arenacea has a significant effect on the function of the pineal gland.

<p>False (B)</p> Signup and view all the answers

What links the pituitary gland to the hypothalamus?

<p>Infundibulum stalk</p> Signup and view all the answers

What type of nerve fibers enter the pineal gland and form synapses with pinealocytes?

<p>Unmyelinated sympathetic nerve fibers</p> Signup and view all the answers

Melatonin release is promoted by __________ and inhibited by __________.

<p>darkness, daylight</p> Signup and view all the answers

Match the components with their functions related to the pineal gland:

<p>Pinealocytes = Produce melatonin Corporeal arenacea = Calcium and magnesium concretions Sympathetic nerve fibers = Regulate melatonin secretion Glial cells = Support and protect nerve cells</p> Signup and view all the answers

Which group of cells within the pineal gland has a characteristic basophilic cytoplasm?

<p>Pinealocytes (A)</p> Signup and view all the answers

The cycle of light and darkness is detected within the retinas and transmitted to the pineal gland.

<p>True (A)</p> Signup and view all the answers

What is the effect of darkness on blood melatonin levels?

<p>Promotes an increase</p> Signup and view all the answers

Flashcards

What is the endocrine system and how does it work?

The endocrine system is one of two major control systems in the body, the other being the nervous system. It regulates body function through the production and release of hormones, which are transported through the bloodstream to target organs. Hormones act slowly, taking minutes to days to exert their effects, and operate at low concentrations.

What makes endocrine glands unique?

Endocrine glands are ductless, meaning they release hormones directly into the bloodstream without using ducts to transport secretions.

How are endocrine gland cells organized?

Endocrine glands have specialized cells organized into structures like columns, glomeruli, follicles, or groups, with at least one surface facing a blood capillary. This arrangement allows efficient release of hormones into the bloodstream.

What kind of blood vessels are found in endocrine glands?

Endocrine glands are richly supplied with fenestrated capillaries, which have large pores allowing for easy passage of hormones into the bloodstream.

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Where is the Pituitary gland located?

The Pituitary gland, also known as the hypophysis cerebri, is located at the base of the skull, tucked into a bony depression called the sella turcica.

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What are the main parts of the Pituitary gland?

The Pituitary gland has a front lobe called the anterior pituitary (adenohypophysis) and a back lobe called the posterior pituitary (neurohypophysis).

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What are the parts of the anterior pituitary?

The anterior pituitary lobe consists of three parts: the pars distalis, pars tuberalis, and pars intermedia.

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What is the pars distalis?

The pars distalis is the largest part of the anterior pituitary and plays a crucial role in hormone synthesis and secretion.

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Pars Intermedia

A region in the anterior pituitary that consists of basophils and contains colloid-filled cysts. It is located between the pars distalis and pars nervosa.

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Chromophils - Acidophils

Cells in the pars distalis of the anterior pituitary that stain with acidic dyes. They have granular cytoplasm and include somatotrophs, lactotrophs, corticotrophs, and gonadotrophs.

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Chromophobes

Cells in the pars distalis of the anterior pituitary that do not stain readily with common histological stains. They have smaller size and non-granular cytoplasm compared to chromophils.

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Somatotrophs

Cells in the pars distalis that secrete growth hormone (GH) responsible for growth and development.

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Lactotrophs

Cells in the pars distalis that secrete prolactin, hormone responsible for milk production in females.

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Fibers of the Pars Nervosa

Unmyelinated axons of magnocellular neurosecretory cells present in the supraoptic and paraventricular nuclei of the hypothalamus. They traverse through the infundibulum and reach the posterior lobe.

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Pars Nervosa

The posterior lobe of the pituitary gland composed of fibers and cells.

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Infundibulum

The stalk that connects the pituitary gland to the hypothalamus.

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Hypothalamic-Hypophyseal Portal System

A specialized blood vessel system that connects the hypothalamus to the anterior pituitary, allowing for the transport of hypothalamic hormones to regulate hormone secretion in the pituitary.

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Hypothalamic-Hypophyseal Tract

A network of nerve fibers that connects the hypothalamus to the posterior pituitary, allowing for the transport of hypothalamic hormones directly into the bloodstream.

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ADH and Oxytocin Synthesis and Release

Antidiuretic hormone (ADH) and oxytocin are synthesized by large neurons in the supraoptic and paraventricular nuclei, respectively. They are then transported down axons of the hypothalamic-hypophyseal tract and released into the bloodstream from the posterior pituitary.

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Hypothalamic Releasing and Inhibiting Hormones

Hormones produced by the hypothalamus that regulate hormone secretion in the anterior pituitary. They are released from axons in the median eminence and transported through the portal system to the anterior pituitary.

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Anterior Pituitary Hormones

Hormones secreted by the anterior pituitary, like growth hormone, that play roles in various bodily functions.

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Location of the Pineal Gland

The pineal gland is located in the brain, shaped like a pine cone.

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Pineal Gland Development

The pineal gland develops from the same embryonic tissue as the brain.

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Herring Bodies

Dilated areas along the axons of the hypothalamic-hypophyseal tract where hormones are stored in the posterior pituitary. They appear as faintly basophilic structures under a microscope.

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Pituicytes

Specialized glial cells found in the posterior pituitary that support the neurons and their axons carrying hormones.

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What hormones does the Posterior Pituitary release?

Hormones released by the posterior pituitary: ADH (Antidiuretic Hormone) regulates water reabsorption and oxytocin is involved in uterine contractions and milk release.

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How does ADH regulate water balance?

ADH is released in response to increased blood tonicity, sensed by osmoreceptors in the hypothalamus. It increases permeability of renal collecting ducts to water, promoting water reabsorption and regulating osmotic balance.

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Blood Supply of the Pituitary: Superior Hypophyseal Arteries

The superior hypophyseal arteries supply the median eminence and the infundibular stalk.

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Blood Supply of the Pituitary: Inferior Hypophyseal Arteries

The inferior hypophyseal arteries provide blood mainly for the neurohypophysis (posterior pituitary).

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Primary Plexus of Fenestrated Capillaries

A network of capillaries found in the median eminence and infundibular stalk that allow exchange of substances between the hypothalamus and the pituitary.

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Describe the pineal gland's structure.

The pineal gland, located in the brain, has a unique structure with secretory cells called pinealocytes and calcified structures called corpora arenacea. The gland is enclosed by connective tissue and separated into lobules by septa containing blood vessels, creating a distinct organization.

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What are pinealocytes and what is their function?

Pinealocytes, the main cell type in the pineal gland, have abundant mitochondria, secretory vesicles, and long cytoplasmic processes that extend toward blood capillaries, indicating an endocrine function. They synthesize and release melatonin, a hormone derived from tryptophan.

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What is the innervation and supporting cell type of the pineal gland?

The pineal gland receives unmyelinated sympathetic nerve fibers that synapse with pinealocytes. The gland also contains interstitial glial cells, similar to astrocytes, which support and regulate the environment of the pinealocytes.

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How is melatonin release from the pineal gland regulated?

Melatonin, a hormone produced by the pineal gland, is influenced by light and darkness. Darkness promotes melatonin release, whereas daylight inhibits it. This creates a daily rhythm in blood melatonin levels.

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What are the effects of melatonin on the body?

The rhythmic changes in blood melatonin levels have a significant impact on the hypothalamus, pituitary gland, and other endocrine tissues, contributing to the 24-hour (circadian) rhythm of physiological functions and behaviors.

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How does the pineal gland receive light information?

Light and darkness signals are detected by the retina and transmitted to the pineal gland via the retinohypothalamic tract, suprachiasmatic nucleus, and sympathetic nerve pathways. The pineal gland serves as a transducer, converting light signals into hormonal changes.

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What is the overall function of the pineal gland in the body?

The pineal gland plays a crucial role in regulating the circadian rhythm of physiological functions and behaviors, influencing endocrine activity and contributing to sleep-wake cycles and other daily rhythms.

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What are corpora arenacea and what is their significance?

Corpora arenacea are calcium and magnesium salt concretions found in the pineal gland. These structures increase in number and size with age but have no known effect on the gland's function.

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Study Notes

Endocrine System Overview

  • The endocrine system is one of two major control systems regulating body functions, the other being the nervous system.
  • It synthesizes and secretes hormones in small amounts, distributed via the bloodstream to target organs.
  • Hormones act slowly (minutes to days) and at low concentrations.

Endocrine System Components

  • The endocrine system includes ductless glands (e.g., pituitary, thyroid, parathyroid, adrenal, and pineal).
  • Isolated cells within organs like the islets of Langerhans, gonads, placenta, thymus, and kidneys also contribute.
  • Diffuse neuro-endocrine system cells (DNES-C) are also part of the system.

Histological Features of Endocrine Glands/Cells

  • Endocrine glands lack ducts, directly secreting hormones into the bloodstream.
  • Parenchymal cells are organized into columns, glomeruli, follicles, or groups, with at least one cell surface facing a blood capillary.
  • Glands are richly supplied with fenestrated blood capillaries.

Hormone Producing Cell Types

  • Different hormone types (peptides, amines, steroids) yield different microscopic appearances in hormone-producing cells.
    • Peptides/glycopeptides are synthesized in the rough endoplasmic reticulum and stored in secretory vesicles (e.g., cells of the pituitary gland).
    • Amines are amino acid derivatives like thyroid hormone, epinephrine, and norepinephrine, synthesized and stored in a manner similar to peptide hormones.
    • Steroids are synthesized on demand from cholesterol via enzymes in the mitochondria and smooth ER (e.g., adrenal cortex cells).

Pituitary Gland (Hypophysis Cerebri)

  • Located in the sella turcica of the skull base.
  • Separated into anterior and posterior lobes by a cleft.

Anterior Lobe (Adenohypophysis)

  • Consists of:
    • Pars distalis (75% of mass), arranged in branching cords separated by fenestrated capillaries.
    • Pars tuberalis, wrapping around infundibulum.
    • Pars intermedia, between pars distalis and pars nervosa (contains basophils and colloid cysts).
  • Cells are chromophils (acidophils, basophils) or chromophobes based on staining affinity.
    • Acidophils (37%): Somatotrophs (growth hormone), Lactotrophs (prolactin).
    • Basophils (11%): Thyrotrophs (thyroid-stimulating hormone), Gonadotrophs (follicle-stimulating and luteinizing hormones), Corticotrophs (adrenocorticotropic hormone).
    • Chromophobes (52%): Have no readily apparent granules.
  • Pars intermedia synthesizes a large M.W polypeptide to produce mainly smaller peptide hormones including MSH.

Posterior Lobe (Neurohypophysis)

  • Composed of:
    • Pars nervosa, composed of fibers, cells and rich capillary plexus originating from unmyelinated neurons from supraoptic and paraventricular nuclei of hypothalamus.
    • Infundibulum stalk connecting to hypothalamus.
    • Herring bodies, faintly basophilic, small bodies where neurosecretions are stored.
    • Pituicytes are neuroglial cells in pars nervosa.

Pineal Gland

  • Located in the epithalamus, posterior wall of third ventricle.
  • Pine cone-shaped structure, 5-8mm by 3-5mm.
  • Covered with connective tissue, creating lobules, containing many pinealocytes and blood vessels.
  • Contains corpora arenacea (brain sand) comprised of calcium and magnesium salts.
  • Pinealocytes are secretory cells, have numerous mitochondria and secretory vesicles, and produce melatonin.
  • Unmyelinated sympathetic nerve fibers enter the gland to end near the pinealocytes.
  • Interstitial glial cells (modified astrocytes) are prominent and their distribution & activity is linked to their presence.

Pituitary Gland Blood Supply

  • Derived from superior/inferior hypophyseal arteries, branching into primary/secondary capillary plexuses.
  • Secondary capillary plexus is in adenohypophysis, providing blood to anterior pituitary.
  • Superior hypophyseal arteries supply median eminence and infundibular stalk, providing blood to the neurohypophysis.

Hypothalamic-Hypophyseal Portal System

  • Carries regulatory peptides from the hypothalamus to the anterior pituitary, stimulating/inhibiting hormone release.

Hormone Secretion Control

  • Anterior pituitary cell activities regulated by hypothalamic hormones (releasing/inhibiting) carried by the portal system.

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Description

Test your knowledge on the anatomy and functions of the endocrine system, focusing on the pituitary gland and hormone secretion. This quiz covers key concepts like Herring bodies, neurosecretory bodies, and their roles in hormonal regulation.

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