Podcast
Questions and Answers
What are the Herring bodies primarily known for?
What are the Herring bodies primarily known for?
- Transporting hormones to the bloodstream
- Storing neurosecretory material (correct)
- Maintaining osmotic balance
- Connecting the pituitary gland to the hypothalamus
Pituicytes are endocrine cells that release hormones into the bloodstream.
Pituicytes are endocrine cells that release hormones into the bloodstream.
False (B)
What hormones are associated with the neurosecretory bodies in the neurohypophysis?
What hormones are associated with the neurosecretory bodies in the neurohypophysis?
Oxytocin and ADH
The axons from the supraoptic and __________ nuclei are mainly concerned with oxytocin secretion.
The axons from the supraoptic and __________ nuclei are mainly concerned with oxytocin secretion.
What triggers the release of ADH from the neurosecretory bodies?
What triggers the release of ADH from the neurosecretory bodies?
Match the following components of the pituitary gland with their functions:
Match the following components of the pituitary gland with their functions:
The blood supply of the pituitary gland comes entirely from the internal jugular vein.
The blood supply of the pituitary gland comes entirely from the internal jugular vein.
What is the primary role of the superior hypophyseal arteries?
What is the primary role of the superior hypophyseal arteries?
Which gland is NOT part of the endocrine system?
Which gland is NOT part of the endocrine system?
The endocrine system includes both ductless glands and isolated cells within certain organs.
The endocrine system includes both ductless glands and isolated cells within certain organs.
What do hormone-producing cells in the adrenal cortex synthesize?
What do hormone-producing cells in the adrenal cortex synthesize?
The ______ is a ductless gland located at the base of the skull.
The ______ is a ductless gland located at the base of the skull.
Match the following components of the pituitary gland with their descriptions:
Match the following components of the pituitary gland with their descriptions:
What type of hormones are synthesized by rough endoplasmic reticulum?
What type of hormones are synthesized by rough endoplasmic reticulum?
Amine hormones are synthesized from cholesterol.
Amine hormones are synthesized from cholesterol.
What is the primary function of the endocrine system?
What is the primary function of the endocrine system?
What is the primary role of the hypothalamic-hypophyseal portal system?
What is the primary role of the hypothalamic-hypophyseal portal system?
Antidiuretic hormone (ADH) is synthesized in the paraventricular nuclei.
Antidiuretic hormone (ADH) is synthesized in the paraventricular nuclei.
What are the two peptide hormones synthesized by hypothalamic neurons mentioned?
What are the two peptide hormones synthesized by hypothalamic neurons mentioned?
The pineal gland is also known as the ______.
The pineal gland is also known as the ______.
Which cells produce growth hormone?
Which cells produce growth hormone?
Match the following hormones with their hypothalamic nuclei:
Match the following hormones with their hypothalamic nuclei:
All hypothalamic hormones that affect the anterior pituitary are releasing hormones.
All hypothalamic hormones that affect the anterior pituitary are releasing hormones.
What shape is the pineal gland?
What shape is the pineal gland?
What type of cells are primarily found in the pars intermedia?
What type of cells are primarily found in the pars intermedia?
The pars distalis accounts for 50% of the mass of the pituitary gland.
The pars distalis accounts for 50% of the mass of the pituitary gland.
What is the primary function of melanocyte-stimulating hormone (MSH)?
What is the primary function of melanocyte-stimulating hormone (MSH)?
The neurohypophysis is also known as the ______.
The neurohypophysis is also known as the ______.
Match the following types of cells with their corresponding hormones:
Match the following types of cells with their corresponding hormones:
What is the primary function of the pineal gland?
What is the primary function of the pineal gland?
Which component consists of the unmyelinated axons from magnocellular neurosecretory cells?
Which component consists of the unmyelinated axons from magnocellular neurosecretory cells?
Chromophobes take up histological stains.
Chromophobes take up histological stains.
The presence of corpora arenacea has a significant effect on the function of the pineal gland.
The presence of corpora arenacea has a significant effect on the function of the pineal gland.
What links the pituitary gland to the hypothalamus?
What links the pituitary gland to the hypothalamus?
What type of nerve fibers enter the pineal gland and form synapses with pinealocytes?
What type of nerve fibers enter the pineal gland and form synapses with pinealocytes?
Melatonin release is promoted by __________ and inhibited by __________.
Melatonin release is promoted by __________ and inhibited by __________.
Match the components with their functions related to the pineal gland:
Match the components with their functions related to the pineal gland:
Which group of cells within the pineal gland has a characteristic basophilic cytoplasm?
Which group of cells within the pineal gland has a characteristic basophilic cytoplasm?
The cycle of light and darkness is detected within the retinas and transmitted to the pineal gland.
The cycle of light and darkness is detected within the retinas and transmitted to the pineal gland.
What is the effect of darkness on blood melatonin levels?
What is the effect of darkness on blood melatonin levels?
Flashcards
What is the endocrine system and how does it work?
What is the endocrine system and how does it work?
The endocrine system is one of two major control systems in the body, the other being the nervous system. It regulates body function through the production and release of hormones, which are transported through the bloodstream to target organs. Hormones act slowly, taking minutes to days to exert their effects, and operate at low concentrations.
What makes endocrine glands unique?
What makes endocrine glands unique?
Endocrine glands are ductless, meaning they release hormones directly into the bloodstream without using ducts to transport secretions.
How are endocrine gland cells organized?
How are endocrine gland cells organized?
Endocrine glands have specialized cells organized into structures like columns, glomeruli, follicles, or groups, with at least one surface facing a blood capillary. This arrangement allows efficient release of hormones into the bloodstream.
What kind of blood vessels are found in endocrine glands?
What kind of blood vessels are found in endocrine glands?
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Where is the Pituitary gland located?
Where is the Pituitary gland located?
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What are the main parts of the Pituitary gland?
What are the main parts of the Pituitary gland?
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What are the parts of the anterior pituitary?
What are the parts of the anterior pituitary?
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What is the pars distalis?
What is the pars distalis?
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Pars Intermedia
Pars Intermedia
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Chromophils - Acidophils
Chromophils - Acidophils
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Chromophobes
Chromophobes
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Somatotrophs
Somatotrophs
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Lactotrophs
Lactotrophs
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Fibers of the Pars Nervosa
Fibers of the Pars Nervosa
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Pars Nervosa
Pars Nervosa
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Infundibulum
Infundibulum
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Hypothalamic-Hypophyseal Portal System
Hypothalamic-Hypophyseal Portal System
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Hypothalamic-Hypophyseal Tract
Hypothalamic-Hypophyseal Tract
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ADH and Oxytocin Synthesis and Release
ADH and Oxytocin Synthesis and Release
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Hypothalamic Releasing and Inhibiting Hormones
Hypothalamic Releasing and Inhibiting Hormones
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Anterior Pituitary Hormones
Anterior Pituitary Hormones
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Location of the Pineal Gland
Location of the Pineal Gland
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Pineal Gland Development
Pineal Gland Development
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Herring Bodies
Herring Bodies
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Pituicytes
Pituicytes
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What hormones does the Posterior Pituitary release?
What hormones does the Posterior Pituitary release?
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How does ADH regulate water balance?
How does ADH regulate water balance?
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Blood Supply of the Pituitary: Superior Hypophyseal Arteries
Blood Supply of the Pituitary: Superior Hypophyseal Arteries
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Blood Supply of the Pituitary: Inferior Hypophyseal Arteries
Blood Supply of the Pituitary: Inferior Hypophyseal Arteries
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Primary Plexus of Fenestrated Capillaries
Primary Plexus of Fenestrated Capillaries
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Describe the pineal gland's structure.
Describe the pineal gland's structure.
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What are pinealocytes and what is their function?
What are pinealocytes and what is their function?
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What is the innervation and supporting cell type of the pineal gland?
What is the innervation and supporting cell type of the pineal gland?
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How is melatonin release from the pineal gland regulated?
How is melatonin release from the pineal gland regulated?
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What are the effects of melatonin on the body?
What are the effects of melatonin on the body?
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How does the pineal gland receive light information?
How does the pineal gland receive light information?
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What is the overall function of the pineal gland in the body?
What is the overall function of the pineal gland in the body?
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What are corpora arenacea and what is their significance?
What are corpora arenacea and what is their significance?
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Study Notes
Endocrine System Overview
- The endocrine system is one of two major control systems regulating body functions, the other being the nervous system.
- It synthesizes and secretes hormones in small amounts, distributed via the bloodstream to target organs.
- Hormones act slowly (minutes to days) and at low concentrations.
Endocrine System Components
- The endocrine system includes ductless glands (e.g., pituitary, thyroid, parathyroid, adrenal, and pineal).
- Isolated cells within organs like the islets of Langerhans, gonads, placenta, thymus, and kidneys also contribute.
- Diffuse neuro-endocrine system cells (DNES-C) are also part of the system.
Histological Features of Endocrine Glands/Cells
- Endocrine glands lack ducts, directly secreting hormones into the bloodstream.
- Parenchymal cells are organized into columns, glomeruli, follicles, or groups, with at least one cell surface facing a blood capillary.
- Glands are richly supplied with fenestrated blood capillaries.
Hormone Producing Cell Types
- Different hormone types (peptides, amines, steroids) yield different microscopic appearances in hormone-producing cells.
- Peptides/glycopeptides are synthesized in the rough endoplasmic reticulum and stored in secretory vesicles (e.g., cells of the pituitary gland).
- Amines are amino acid derivatives like thyroid hormone, epinephrine, and norepinephrine, synthesized and stored in a manner similar to peptide hormones.
- Steroids are synthesized on demand from cholesterol via enzymes in the mitochondria and smooth ER (e.g., adrenal cortex cells).
Pituitary Gland (Hypophysis Cerebri)
- Located in the sella turcica of the skull base.
- Separated into anterior and posterior lobes by a cleft.
Anterior Lobe (Adenohypophysis)
- Consists of:
- Pars distalis (75% of mass), arranged in branching cords separated by fenestrated capillaries.
- Pars tuberalis, wrapping around infundibulum.
- Pars intermedia, between pars distalis and pars nervosa (contains basophils and colloid cysts).
- Cells are chromophils (acidophils, basophils) or chromophobes based on staining affinity.
- Acidophils (37%): Somatotrophs (growth hormone), Lactotrophs (prolactin).
- Basophils (11%): Thyrotrophs (thyroid-stimulating hormone), Gonadotrophs (follicle-stimulating and luteinizing hormones), Corticotrophs (adrenocorticotropic hormone).
- Chromophobes (52%): Have no readily apparent granules.
- Pars intermedia synthesizes a large M.W polypeptide to produce mainly smaller peptide hormones including MSH.
Posterior Lobe (Neurohypophysis)
- Composed of:
- Pars nervosa, composed of fibers, cells and rich capillary plexus originating from unmyelinated neurons from supraoptic and paraventricular nuclei of hypothalamus.
- Infundibulum stalk connecting to hypothalamus.
- Herring bodies, faintly basophilic, small bodies where neurosecretions are stored.
- Pituicytes are neuroglial cells in pars nervosa.
Pineal Gland
- Located in the epithalamus, posterior wall of third ventricle.
- Pine cone-shaped structure, 5-8mm by 3-5mm.
- Covered with connective tissue, creating lobules, containing many pinealocytes and blood vessels.
- Contains corpora arenacea (brain sand) comprised of calcium and magnesium salts.
- Pinealocytes are secretory cells, have numerous mitochondria and secretory vesicles, and produce melatonin.
- Unmyelinated sympathetic nerve fibers enter the gland to end near the pinealocytes.
- Interstitial glial cells (modified astrocytes) are prominent and their distribution & activity is linked to their presence.
Pituitary Gland Blood Supply
- Derived from superior/inferior hypophyseal arteries, branching into primary/secondary capillary plexuses.
- Secondary capillary plexus is in adenohypophysis, providing blood to anterior pituitary.
- Superior hypophyseal arteries supply median eminence and infundibular stalk, providing blood to the neurohypophysis.
Hypothalamic-Hypophyseal Portal System
- Carries regulatory peptides from the hypothalamus to the anterior pituitary, stimulating/inhibiting hormone release.
Hormone Secretion Control
- Anterior pituitary cell activities regulated by hypothalamic hormones (releasing/inhibiting) carried by the portal system.
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Description
Test your knowledge on the anatomy and functions of the endocrine system, focusing on the pituitary gland and hormone secretion. This quiz covers key concepts like Herring bodies, neurosecretory bodies, and their roles in hormonal regulation.