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Questions and Answers
Which hormone class is synthesized by endocrine glands and transported in the blood to target cells?
Which hormone class is synthesized by endocrine glands and transported in the blood to target cells?
Peptide hormones can easily cross the cell membrane.
Peptide hormones can easily cross the cell membrane.
False
What is the primary function of hormones in the body?
What is the primary function of hormones in the body?
To help control how cells and organs do their work.
The three major categories of stimuli that activate the endocrine organs are hormonal, humoral, and _____ .
The three major categories of stimuli that activate the endocrine organs are hormonal, humoral, and _____ .
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Match the hormone class with their characteristics:
Match the hormone class with their characteristics:
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Which hormone class is made up of fatty acids and uses cholesterol as a functional group?
Which hormone class is made up of fatty acids and uses cholesterol as a functional group?
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Autocrine hormones act on different cells than the ones that synthesize them.
Autocrine hormones act on different cells than the ones that synthesize them.
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Name one example of a hydrophilic hormone.
Name one example of a hydrophilic hormone.
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Which type of stimulus primarily involves hormone release triggered by other hormones?
Which type of stimulus primarily involves hormone release triggered by other hormones?
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Which hormone is primarily secreted by the thyroid follicles?
Which hormone is primarily secreted by the thyroid follicles?
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The posterior lobe of the pituitary gland produces hormones.
The posterior lobe of the pituitary gland produces hormones.
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What is the primary function of growth hormone (GH) in children?
What is the primary function of growth hormone (GH) in children?
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The hypothalamus is classified as an endocrine gland.
The hypothalamus is classified as an endocrine gland.
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The anterior pituitary produces several hormones, including _____, which stimulates breast milk production after childbirth.
The anterior pituitary produces several hormones, including _____, which stimulates breast milk production after childbirth.
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What are the two hormones derived from the thyroid gland?
What are the two hormones derived from the thyroid gland?
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Match the following hormones with their primary functions:
Match the following hormones with their primary functions:
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The primary function of the hypothalamus is __________.
The primary function of the hypothalamus is __________.
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Match the following hormones with their corresponding glands:
Match the following hormones with their corresponding glands:
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Which of the following accurately describes water-soluble hormones?
Which of the following accurately describes water-soluble hormones?
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What is the function of parathyroid hormone (PTH)?
What is the function of parathyroid hormone (PTH)?
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Sympathetic nervous system stimulation is an example of humoral stimulation for hormone release.
Sympathetic nervous system stimulation is an example of humoral stimulation for hormone release.
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What is the primary role of the hypothalamus in relation to the anterior pituitary?
What is the primary role of the hypothalamus in relation to the anterior pituitary?
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Calcitonin hormone is produced by the thyroid follicles.
Calcitonin hormone is produced by the thyroid follicles.
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What triggers the release of parathyroid hormone (PTH)?
What triggers the release of parathyroid hormone (PTH)?
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Which hormone causes the ovarian follicle to rupture and release the ovum?
Which hormone causes the ovarian follicle to rupture and release the ovum?
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Progesterone supports the development of secondary sex characteristics in women.
Progesterone supports the development of secondary sex characteristics in women.
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What is the primary function of testosterone in males?
What is the primary function of testosterone in males?
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The ______ secretes estrogen during the ovarian cycle.
The ______ secretes estrogen during the ovarian cycle.
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Match the hormone with its primary role:
Match the hormone with its primary role:
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During pregnancy, progesterone plays a role in which of the following?
During pregnancy, progesterone plays a role in which of the following?
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The adrenal glands are comprised of a single endocrine organ.
The adrenal glands are comprised of a single endocrine organ.
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What are the two main groups of steroid hormones produced by the ovaries?
What are the two main groups of steroid hormones produced by the ovaries?
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What is the primary function of the thymus gland?
What is the primary function of the thymus gland?
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Erythropoietin is a hormone produced by the stomach.
Erythropoietin is a hormone produced by the stomach.
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What hormone is released by the placenta during pregnancy?
What hormone is released by the placenta during pregnancy?
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The hormone ________ stimulates the release of hydrochloric acid in the stomach.
The hormone ________ stimulates the release of hydrochloric acid in the stomach.
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Match the following hormones with their functions:
Match the following hormones with their functions:
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What is the primary role of glucocorticoids?
What is the primary role of glucocorticoids?
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Aldosterone causes the retention of K ions in the body.
Aldosterone causes the retention of K ions in the body.
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Name one hormone produced by the adrenal medulla that enhances the 'fight or flight' response.
Name one hormone produced by the adrenal medulla that enhances the 'fight or flight' response.
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The hormone __________ is secreted when blood pressure drops, stimulating the release of aldosterone.
The hormone __________ is secreted when blood pressure drops, stimulating the release of aldosterone.
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Match the gland with its respective hormone.
Match the gland with its respective hormone.
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What effect do glucocorticoids have on the immune system?
What effect do glucocorticoids have on the immune system?
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What happens to water when Na ions are reabsorbed due to aldosterone?
What happens to water when Na ions are reabsorbed due to aldosterone?
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All sex hormones in both males and females are produced in equal quantities by the adrenal glands.
All sex hormones in both males and females are produced in equal quantities by the adrenal glands.
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Study Notes
Endocrine System Overview
- The endocrine system is a collection of glands that produce hormones.
- Hormones regulate metabolism, growth, development, tissue function, sexual function, reproduction, sleep, and mood.
- Hormones circulate throughout the body, affecting specific organs and tissues.
- The term "endocrine" comes from Greek words meaning "within" and "to secrete".
Endocrine System Objectives
- Define the endocrine system and its general function.
- Explain how the endocrine system maintains homeostasis.
- Explain the relationship between the endocrine system and the nervous system.
- Differentiate between endocrine and exocrine glands.
- Define hormones, their functions, and types.
- Describe ways to keep the endocrine system healthy.
General Function of Hormones
- Regulates extracellular fluid, metabolism, biological clock, contraction of cardiac and smooth muscle, glandular secretion, and some immune functions.
- Plays a role in growth and development, and reproduction.
General Function of the Endocrine System
- Receives support from other organs like kidneys, liver, heart, and gonads.
- These organs are secondary components of the endocrine system, performing endocrine functions.
- The kidney, for instance, secretes hormones such as erythropoietin and renin.
Types of Endocrine Glands
- Endocrine glands release hormones directly into the bloodstream (ductless).
- Exocrine glands release substances into ducts, either outside the body or into internal spaces (e.g., digestive glands, sweat glands).
Definition of Hormones
- Hormones are chemical messengers that act like messenger molecules in the body.
- Hormones are made in one part of the body.
- These messengers travel to other parts of the body and control how cells and organs function.
Important Functions of Hormones
- Growth and development (cell and tissue)
- Food metabolism
- Initiating and maintaining sexual development and reproduction
- Maintaining body temperature
- Controlling thirst
- Regulating mood and cognitive functioning
Types of Hormones (Classification)
- Classified by their proximity to the site of synthesis to their site of action (autocrine, paracrine, endocrine).
- Classified by their chemical structure (peptides/proteins, steroids).
- Classified by their solubility in aqueous (hydrophilic/liposoluble) medium.
Three Classes of Hormones
- Autocrine hormones act on the same cells that produce them.
- Paracrine hormones act on nearby cells.
- Endocrine hormones travel through the blood to target cells.
Four Classes of Hormones (Based on Chemical Structure)
- Peptides/proteins are made of amino acids joined by peptide bonds.
- Steroid hormones are made of fatty acids using cholesterol as a functional group.
- Amino acid derivatives
- Fatty acid derivatives
Two Classes of Hormones (Based on Solubility)
- Hydrophilic hormones (e.g., insulin, glucagon, and epinephrine) are soluble in water, and cannot cross the cell membrane.
- Lipophilic hormones (e.g., thyroid hormones and steroid hormones) are not soluble in water, but they can cross the cell membrane.
Control of Hormone Release
- Hormonal stimuli: Endocrine organs are activated by other hormones.
- Humoral stimuli: Changing blood levels of ions and nutrients.
- Neural stimuli: Nerve fibers stimulate hormone release.
Hormone Transport in Blood
- Hormones flow through the blood and bind to receptors within capillaries.
- Water-insoluble hormones bind to plasma proteins to be carried into the blood.
- Water-soluble hormones dissolve into the plasma.
Pituitary Gland
- The pituitary gland is a small, bean-shaped structure in the head.
- It receives signals from the hypothalamus and can release/inhibit hormones.
- The pituitary gland has two main lobes: anterior and posterior.
- The anterior pituitary produces and releases various hormones.
- The posterior pituitary releases hormones produced by the hypothalamus.
Anterior Pituitary Hormones
- Growth hormone (GH): Essential for growth and body composition. Important for children and adults, affects fat distribution and protein synthesis.
- Prolactin: Stimulates breast milk production after childbirth.
- Follicle-stimulating hormone (FSH): Works with LH to ensure normal function and development of the ovaries and testes, and the production of sperm and egg.
- Luteinizing hormone (LH): Works with FSH to ensure normal function of the ovaries and testes; triggers ovulation in females and stimulates testosterone production in males.
- Adrenocorticotropic hormone (ACTH): Stimulates the adrenal glands to produce hormones.
- Thyroid-stimulating hormone (TSH): Stimulates the thyroid gland to produce hormones.
Posterior Pituitary Hormones
- Antidiuretic hormone (ADH) (or Vasopressin): Maintains blood pressure, blood volume, and water content. Acts at kidney level on water reabsorption.
- Oxytocin: Involved in processes such as contracting the uterus during childbirth and stimulating breast milk production.
Pineal Gland
- The pineal gland is located in the back portion of the third cerebral ventricle of the brain.
- It is also known as the "pineal body".
- Its function is not fully understood, but it appears to play a role in regulating female reproduction, sexual maturation, circadian rhythms (such as sleep-wake cycles), and the body's internal clock.
- Pinealocytes produce and secrete melatonin; regulating female reproductive hormones, including menstruation.
Thyroid Gland
- The thyroid gland is located at the base of the throat.
- It is a large gland consisting of two lobes connected by an isthmus.
- The thyroid gland produces two main hormones: thyroxine (T4) and triiodothyronine (T3).
- It also produces calcitonin.
- T4 and T3 are produced from follicles and are essential for metabolic functions such as metabolism of energy sources (oxidation and conversion to chemical energy), and converting glucose into body heat.
- Calcitonin regulates calcium levels.
Parathyroid Gland
- The parathyroid glands are small glands located on the posterior aspect of the thyroid gland.
- The parathyroid glands release parathyroid hormone (PTH) in response to low blood calcium levels.
- PTH causes bone calcium release into the blood and stimulates calcium absorption in the kidneys and intestine.
Hypothalamus
- Part of the brain, located below the thalamus.
- It controls the pituitary gland's hormone secretion and regulates various body functions, including temperature maintenance, thirst, hunger, sleep, mood, and blood pressure.
Gonads
- The female (ovaries) and male (testes) gonads function as both exocrine (producing sex cells) and endocrine glands (producing sex hormones).
- Sex hormones produced by both the ovaries and testes are chemically identical, though the quantities vary between the two.
Ovaries
- The paired, almond-shaped ovaries are in the female pelvic cavity.
- Ovaries produce female sex cells (ova) and estrogen and progesterone.
- Estrogen promotes the development of secondary sexual characteristics and controls the menstrual cycle.
- Progesterone supports a pregnancy.
Testes
- The paired testes are located outside the female pelvic cavity in a sac called the scrotum.
- The testes produce sperm and testosterone.
- Testosterone promotes male secondary sexual characteristics and supports sperm production.
Adrenal Glands
- The adrenal glands are located on top of each kidney.
- They are composed of two parts: the adrenal medulla and the adrenal cortex.
- The adrenal cortex produces corticosteroids, such as mineralocorticoids (e.g., aldosterone) that regulate minerals and glucocorticoids (e.g., cortisol) that regulate glucose and help the body respond to stress.
- The adrenal medulla produces epinephrine and norepinephrine, part of the body's "fight or flight" response. These hormones enhance the body's reaction to an emergency.
Thymus Gland
- The thymus gland is located in the thoracic cavity, behind the sternum.
- It produces various thymosins and other hormones that regulate the maturation of T-cells, which are important for the immune system's function.
Kidney
- Kidneys produce renin, which helps regulate blood pressure.
- They produce erythropoietin, which stimulates red blood cell production.
- They produce calcitriol, which stimulates calcium absorption in the intestine.
Stomach and Intestine
- The stomach contains gastrin, which promotes the production of hydrochloric acid.
- The intestine contains secretin, which promotes the production of bicarbonate.
Other Endocrine Tissues & Organs
-
Heart:
- Produces atriopeptin (ANP)
-
Adipose Tissues:
- Produce leptin and resistin
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Description
Test your knowledge on the endocrine system with this quiz covering hormone classes, functions, and the stimuli that activate endocrine organs. Answer questions about peptide hormones, autocrine functions, and the role of the hypothalamus. Perfect for students studying human physiology.