Endocrine Pathophysiology Quiz

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What is the most common cause of Syndrome of inappropriate antidiuretic hormone (SIADH) secretion?

Dysfunction of the posterior pituitary

Altered hormone inactivation

Ectopic secretion of ADH (correct)

Failure of feedback systems

How does ADH affect the renal collecting ducts in SIADH?

Stimulates sodium reabsorption

Inhibits chloride reabsorption

Increases their permeability to water (correct)

Decreases their permeability to water

What characterizes the volume status in nephrogenic form of SIADH?

Dehydration

Euvolemia (correct)

Hypervolemia

Hypovolemia

Which parameter remains unchanged in the syndrome of inappropriate antidiuretic hormone (SIADH)?

Total body sodium Signup and view all the answers

What is a common characteristic of hyponatremia in SIADH?

Euvolemic hypotonic hyponatremia Signup and view all the answers

Which gland dysfunction is associated with Syndrome of inappropriate antidiuretic hormone (SIADH)?

Posterior pituitary dysfunction Signup and view all the answers

What type of hormonal alteration is observed in Syndrome of inappropriate antidiuretic hormone (SIADH)?

Hypersecretion of antidiuretic hormone (ADH) Signup and view all the answers

What is the major characteristic of hyponatremia in the nephrogenic form of SIADH?

Euvolemic hypotonic hyponatremia Signup and view all the answers

What type of feedback system failure can lead to Syndrome of inappropriate antidiuretic hormone (SIADH)?

Diminished feedback sensitivity Signup and view all the answers

Which of the following is NOT a characteristic of euvolemic hypotonic hyponatremia in SIADH?

Edema presence Signup and view all the answers

What is the primary action of antidiuretic hormone (ADH) on renal collecting ducts in SIADH?

Increase water reabsorption Signup and view all the answers

Which condition must coexist for the diagnosis of Syndrome of inappropriate antidiuretic hormone (SIADH)?

Normal renal, adrenal, and thyroid function Signup and view all the answers

What is the primary cause of Syndrome of inappropriate antidiuretic hormone (SIADH)?

Ectopic hormone release Signup and view all the answers

In SIADH, what characterizes the volume status and edema?

Euvolemia and absence of edema Signup and view all the answers

What distinguishes nephrogenic form from other forms of SIADH in terms of hyponatremia?

Increased extracellular fluid Signup and view all the answers

Which factor is NOT typically altered in patients with Syndrome of inappropriate antidiuretic hormone (SIADH)?

Total body sodium Signup and view all the answers

What distinguishes euvolemic hyponatremia in SIADH from other types of hyponatremia?

Increased total body water Signup and view all the answers

Which mechanism contributes to the altered hormonal state in Syndrome of inappropriate antidiuretic hormone (SIADH)?

Target cell dysfunction Signup and view all the answers