Endocrine Pathophysiology Quiz
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Questions and Answers

What is the most common cause of Syndrome of inappropriate antidiuretic hormone (SIADH) secretion?

  • Dysfunction of the posterior pituitary
  • Altered hormone inactivation
  • Ectopic secretion of ADH (correct)
  • Failure of feedback systems

How does ADH affect the renal collecting ducts in SIADH?

  • Stimulates sodium reabsorption
  • Inhibits chloride reabsorption
  • Increases their permeability to water (correct)
  • Decreases their permeability to water

What characterizes the volume status in nephrogenic form of SIADH?

  • Dehydration
  • Euvolemia (correct)
  • Hypervolemia
  • Hypovolemia

Which parameter remains unchanged in the syndrome of inappropriate antidiuretic hormone (SIADH)?

<p>Total body sodium (D)</p> Signup and view all the answers

What is a common characteristic of hyponatremia in SIADH?

<p>Euvolemic hypotonic hyponatremia (D)</p> Signup and view all the answers

Which gland dysfunction is associated with Syndrome of inappropriate antidiuretic hormone (SIADH)?

<p>Posterior pituitary dysfunction (D)</p> Signup and view all the answers

What type of hormonal alteration is observed in Syndrome of inappropriate antidiuretic hormone (SIADH)?

<p>Hypersecretion of antidiuretic hormone (ADH) (B)</p> Signup and view all the answers

What is the major characteristic of hyponatremia in the nephrogenic form of SIADH?

<p>Euvolemic hypotonic hyponatremia (B)</p> Signup and view all the answers

What type of feedback system failure can lead to Syndrome of inappropriate antidiuretic hormone (SIADH)?

<p>Diminished feedback sensitivity (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of euvolemic hypotonic hyponatremia in SIADH?

<p>Edema presence (B)</p> Signup and view all the answers

What is the primary action of antidiuretic hormone (ADH) on renal collecting ducts in SIADH?

<p>Increase water reabsorption (B)</p> Signup and view all the answers

Which condition must coexist for the diagnosis of Syndrome of inappropriate antidiuretic hormone (SIADH)?

<p>Normal renal, adrenal, and thyroid function (A)</p> Signup and view all the answers

What is the primary cause of Syndrome of inappropriate antidiuretic hormone (SIADH)?

<p>Ectopic hormone release (D)</p> Signup and view all the answers

In SIADH, what characterizes the volume status and edema?

<p>Euvolemia and absence of edema (D)</p> Signup and view all the answers

What distinguishes nephrogenic form from other forms of SIADH in terms of hyponatremia?

<p>Increased extracellular fluid (A)</p> Signup and view all the answers

Which factor is NOT typically altered in patients with Syndrome of inappropriate antidiuretic hormone (SIADH)?

<p>Total body sodium (B)</p> Signup and view all the answers

What distinguishes euvolemic hyponatremia in SIADH from other types of hyponatremia?

<p>Increased total body water (B)</p> Signup and view all the answers

Which mechanism contributes to the altered hormonal state in Syndrome of inappropriate antidiuretic hormone (SIADH)?

<p>Target cell dysfunction (B)</p> Signup and view all the answers

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