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Endocrine Content Study Guide and Quiz

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Questions and Answers

What is the cause of neurogenic diabetes insipidus?

Elevated levels of ADH without the usual stimuli

Inadequate release and synthesis of ADH

Inability to concentrate urine and excrete large urine

Trauma, surgery, and tumor (correct)

What are the effects of elevated levels of ADH in SIADH?

Plasma dilution due to water retention (correct)

Dilute hyponatremia

Increased specific gravity and urine sodium concentration

Inability to concentrate urine and excrete large urine

What is the pharmacotherapy for SIADH?

Inadequate synthesis and release of ADH

Insulin

Corticosteroids

Conivaptan: IV, Tolvaptan: oral (correct)

What characterizes the pathophysiology of diabetes insipidus?

Inadequate synthesis and release of ADH Signup and view all the answers

What is the cause of hypo/hyperpituitarism?

Hypofunction or hyperfunction of the pituitary gland Signup and view all the answers

What is the primary pharmacotherapy for SIADH?

Tolvaptan: oral Signup and view all the answers

What is the cause of hyperfunction of the adrenal cortex?

Excessive secretion of cortisol Signup and view all the answers

What is the effect of elevated levels of ADH in SIADH on fluid balance?

Increased urine concentration Signup and view all the answers

What characterizes the pathophysiology of hypofunction of the adrenal cortex?

Inadequate secretion of cortisol Signup and view all the answers

What occurs with ADH levels in diabetes insipidus?

Inability to concentrate urine and excrete large urine Signup and view all the answers