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Questions and Answers
What is the primary focus of Endocrine Case Management: Meet the Professor?
Who is the intended audience for Endocrine Case Management: Meet the Professor?
Which aspect does the content feature for maintaining current practices in endocrinology?
What type of expertise is represented in the content of Endocrine Case Management?
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What format is used in the Endocrine Case Management: Meet the Professor to present its materials?
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Which of the following features must be enabled in the browser to ensure proper functionality regarding content access?
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What should be enabled along with cookies for optimal performance in a web browser?
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What is the consequence of not enabling cookies in a browser?
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Why is it important to enable Javascript in the browser?
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Which of the following statements is true regarding browser settings?
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What is the primary cause of LDL elevation in familial hypercholesterolemia?
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Which technique is commonly used to measure LDL levels due to the limitation of other methods?
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What does not readily discriminate reduced LDL-receptor levels in patients?
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What condition can be a consequence of reduced LDL-receptor levels?
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What is the primary function of LDL-receptors in the body?
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What is indicated by elevated plasma triglyceride levels?
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Reduced HDL levels are associated with which of the following conditions?
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Why might measurement of total and LDL cholesterol be misleading?
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What is a consequence of high plasma triglyceride levels?
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What is the role of LDL particles in atherosclerotic cardiovascular disease (ASCVD)?
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What is inhibited in cases of small and medium LDL particle subclasses?
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What characteristic of small and medium LDL particles contributes to their increased susceptibility to oxidation?
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What type of genetic markers are associated with small and medium LDL particle subclasses?
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What role does plasminogen play in cardiovascular health?
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What factor is most likely to contribute to the instability of small and medium LDL particles?
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Study Notes
Endocrine Case Management
- Case-based clinical vignettes provide practical insights from experts in endocrinology, diabetes, and metabolism.
- Intended for healthcare professionals aiming to stay updated in their practice.
Familial Hypercholesterolemia
- Reduced LDL-receptor levels cause LDL elevation associated with familial hypercholesterolemia.
- Pathological inhibition of plasminogen-induced clot lysis is linked to decreased LDL receptors.
- Increased risk of LDL particle oxidation due to high disulfide bond content.
Lipid Metrics and Cardiovascular Disease
- LDL particles are crucial in the development and progression of Atherosclerotic Cardiovascular Disease (ASCVD).
- Total and LDL cholesterol measurements can misrepresent actual LDL particle concentrations, potentially leading to inaccurate assessments.
- Elevated plasma triglycerides indicate high levels of partially catabolized triglyceride-rich lipoproteins and remnants, important for assessing cardiovascular risk.
Testing Techniques
- LDL particle concentrations often require immunoassay methods due to limitations in nuclear magnetic resonance and ion mobility techniques.
- Measurement of lipid profiles must consider the nuances of triglyceride and HDL cholesterol levels for accurate cardiovascular risk evaluation.
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Description
Explore clinical insights on endocrinology, diabetes, and lipid metrics related to cardiovascular disease. This quiz is designed for healthcare professionals seeking to enhance their understanding of familial hypercholesterolemia and its implications for ASCVD. Stay updated with expert perspectives through case-based scenarios.
