Podcast
Questions and Answers
What is the primary pathogenic mechanism underlying the development of emphysema?
What is the primary pathogenic mechanism underlying the development of emphysema?
- Decreased activity of proteolytic enzymes like elastase
- Destruction of alveolar walls due to elastase activity (correct)
- Increased mucus production in the airways
- Increased production of alpha-1 antitrypsin
Which of the following is a common complication of emphysema in COPD?
Which of the following is a common complication of emphysema in COPD?
- Lung abscess
- Interstitial emphysema (correct)
- Interstitial fibrosis
- Pulmonary edema
What is the primary cause of alpha-1 antitrypsin deficiency, which can lead to panacinar emphysema?
What is the primary cause of alpha-1 antitrypsin deficiency, which can lead to panacinar emphysema?
- Variants in the pi (proteinase inhibitor) gene on chromosome 14 (correct)
- Chronic exposure to cigarette smoke
- Increased production of proteolytic enzymes
- Autoimmune destruction of alveolar walls
Which of the following is a characteristic feature of bronchiectasis?
Which of the following is a characteristic feature of bronchiectasis?
Which of the following is a common comorbidity associated with emphysema in COPD?
Which of the following is a common comorbidity associated with emphysema in COPD?
What is the primary histologic characteristic of chronic bronchitis in COPD?
What is the primary histologic characteristic of chronic bronchitis in COPD?
What is the histologic characteristic associated with centriacinar emphysema?
What is the histologic characteristic associated with centriacinar emphysema?
Which type of emphysema is strongly associated with cigarette smoking?
Which type of emphysema is strongly associated with cigarette smoking?
What is the clinical presentation specifically associated with chronic bronchitis in COPD?
What is the clinical presentation specifically associated with chronic bronchitis in COPD?
Which type of emphysema is associated with loss of elasticity and sometimes deficiency of alpha 1 antitrypsin?
Which type of emphysema is associated with loss of elasticity and sometimes deficiency of alpha 1 antitrypsin?
What microscopically distinguishes chronic obstructive pulmonary disease (COPD) III - Emphysema from other types of emphysema?
What microscopically distinguishes chronic obstructive pulmonary disease (COPD) III - Emphysema from other types of emphysema?
Which type of emphysema tends to localize subjacent to the pleura and inter-lobar septa?
Which type of emphysema tends to localize subjacent to the pleura and inter-lobar septa?
Which of the following is a typical histologic characteristic of chronic bronchitis in COPD?
Which of the following is a typical histologic characteristic of chronic bronchitis in COPD?
Which of the following is a complication of chronic bronchitis in COPD?
Which of the following is a complication of chronic bronchitis in COPD?
Which of the following is NOT a clinical presentation of chronic bronchitis in COPD?
Which of the following is NOT a clinical presentation of chronic bronchitis in COPD?
Which of the following is a characteristic of emphysema in COPD?
Which of the following is a characteristic of emphysema in COPD?
Which of the following is a clinico-pathological characteristic of emphysema in COPD?
Which of the following is a clinico-pathological characteristic of emphysema in COPD?
Which of the following is a radiographic finding in emphysema in COPD?
Which of the following is a radiographic finding in emphysema in COPD?
