Podcast
Questions and Answers
What induces the formation of mesoderm from the organiser tissue?
What induces the formation of mesoderm from the organiser tissue?
- Induction by BMP inhibitors
- VegT + beta-catenin
- High levels of nodal + siamois (correct)
- Ectodermin and Norrin
Which factor induces the production of Xnrs for endoderm formation?
Which factor induces the production of Xnrs for endoderm formation?
- Foxi2
- Beta-catenin
- Noggin
- VegT (correct)
What is the significance of Spemann’s organiser grafting experiment in understanding neural tissue induction?
What is the significance of Spemann’s organiser grafting experiment in understanding neural tissue induction?
- When removed, neural tube formation is inhibited
- It inhibits the production of VegT
- Transplanting the organiser onto another embryo induces neural tube formation (correct)
- It induces the production of BMP inhibitors
Which proteins are secreted by Spemann’s organiser to inhibit the production of neural tissue?
Which proteins are secreted by Spemann’s organiser to inhibit the production of neural tissue?
In Spemann’s organiser grafting experiment, what happens when the organiser is removed?
In Spemann’s organiser grafting experiment, what happens when the organiser is removed?
Which factor induces the production of Xema for ectodermal fate induction?
Which factor induces the production of Xema for ectodermal fate induction?
What is the role of Coco in ectoderm induction?
What is the role of Coco in ectoderm induction?
What is the role of VegT in the formation of endoderm?
What is the role of VegT in the formation of endoderm?
Which protein is responsible for inducing high levels of nodal and siamois in the organiser tissue?
Which protein is responsible for inducing high levels of nodal and siamois in the organiser tissue?
What is the function of Xnr3 in neural tissue induction?
What is the function of Xnr3 in neural tissue induction?
Which signal is inhibited by the organiser to allow mesoderm formation?
Which signal is inhibited by the organiser to allow mesoderm formation?
What is the consequence of high levels of nodal signaling in the dorsal side?
What is the consequence of high levels of nodal signaling in the dorsal side?
What induces the production of Sox17 for endoderm formation?
What induces the production of Sox17 for endoderm formation?
What is the role of Foxi2 in ectodermal fate induction?
What is the role of Foxi2 in ectodermal fate induction?
What is the role of BMP in the induction of neural tissue from ectoderm?
What is the role of BMP in the induction of neural tissue from ectoderm?
What is the function of chordin, noggin, follistatin, and Xnr3 secreted by Spemann’s organiser?
What is the function of chordin, noggin, follistatin, and Xnr3 secreted by Spemann’s organiser?
What happens when Spemann’s organiser is removed in the context of neural tissue induction?
What happens when Spemann’s organiser is removed in the context of neural tissue induction?
Which signal is inhibited by Spemann’s organiser to allow mesoderm formation?
Which signal is inhibited by Spemann’s organiser to allow mesoderm formation?
What induces the production of Sox17 for endoderm formation?
What induces the production of Sox17 for endoderm formation?
What is the consequence of high levels of nodal signaling in the dorsal side?
What is the consequence of high levels of nodal signaling in the dorsal side?
Which protein is responsible for inducing high levels of nodal and siamois in the organiser tissue?
Which protein is responsible for inducing high levels of nodal and siamois in the organiser tissue?
What is the role of Foxi2 in ectodermal fate induction?
What is the role of Foxi2 in ectodermal fate induction?
What induces the production of Xema for ectodermal fate induction?
What induces the production of Xema for ectodermal fate induction?
What is the role of Coco in ectoderm induction?
What is the role of Coco in ectoderm induction?
Study Notes
Formation of Mesoderm from Organizer Tissue
- The formation of mesoderm from organizer tissue is induced by the inhibition of BMP signal.
Endoderm Formation
- Xnrs are induced for endoderm formation by VegT.
- Sox17 is induced for endoderm formation by VegT.
Neural Tissue Induction
- The significance of Spemann's organizer grafting experiment lies in its demonstration of neural tissue induction.
- Chordin, noggin, follistatin, and Xnr3 are secreted by Spemann's organizer to inhibit the production of neural tissue.
- Xnr3 induces the production of nodal and siamois in the organizer tissue.
- Xnr3 is involved in neural tissue induction.
Ectodermal Fate Induction
- Xema is induced for ectodermal fate induction by Coco.
- Foxi2 is involved in ectodermal fate induction.
- The role of Coco is to induce Xema for ectodermal fate induction.
- Foxi2 plays a role in inducing ectodermal fate.
Neural Tissue Inhibition
- BMP signal is inhibited by Spemann's organizer to allow mesoderm formation.
- The consequence of high levels of nodal signaling in the dorsal side is the inhibition of neural tissue induction.
Organizer Tissue Removal
- When Spemann's organizer is removed, neural tissue induction is allowed to occur.
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Description
Test your knowledge of the signals involved in setting up the three germ layers and gastrulation process during embryonic development. This quiz covers the induction of mesoderm and endoderm, including the role of nodal, siamois, VegT, beta-catenin, Xnrs, and BMP.