Embryonic Development: History and Concepts
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Questions and Answers

Which of the following is a fundamental stage of embryonic development?

  • Cell specification
  • Cell differentiation
  • Cell competence
  • Gastrulation (correct)

What promotes the activity of smoothened signaling in the sonic hedgehog (Shh) pathway?

  • Facial abnormalities
  • Cholesterol (correct)
  • Cyclopamine
  • Mutations in Shh pathway proteins

Which plant product inhibits smoothened signaling in the sonic hedgehog (Shh) pathway?

  • Facial abnormalities
  • Cholesterol
  • Cyclopamine (correct)
  • Mutations in Shh pathway proteins

What do mutations in sonic hedgehog (Shh) pathway proteins cause?

<p>Facial abnormalities (A)</p> Signup and view all the answers

What are the three progressive states of embryonic cells that need to be resolved?

<p>Specification, determination, differentiation (C)</p> Signup and view all the answers

What concept generally describes the ability of a cell to respond to morphogen signals?

<p>Cellular competence (D)</p> Signup and view all the answers

What is the primary process involved in the generation of a new shape during development?

<p>Cell movement (B)</p> Signup and view all the answers

What does induction refer to in embryonic cell development?

<p>The ability of a cell to respond to inductive signals (B)</p> Signup and view all the answers

What is the mechanism by which cells 'know' their position along a line with respect to boundaries at either end?

<p>Morphogen concentration gradient (C)</p> Signup and view all the answers

Which type of cell behavior primarily contributes to establishing an ordered body plan and specifying A/P, D/V axes?

<p>Cell proliferation (D)</p> Signup and view all the answers

What is the ability of a cell to respond to inductive signals known as?

<p>Competence (B)</p> Signup and view all the answers

Which process primarily involves cells becoming structurally and functionally different?

<p>Cell differentiation (C)</p> Signup and view all the answers

What is the term used for the gradual changes that cells go through before acquiring their final fate?

<p>Developmental progression (B)</p> Signup and view all the answers

What can mutations in human EXT1 and EXT2 genes result in?

<p>Bone exostoses (C)</p> Signup and view all the answers

Which of the following is NOT one of the five fundamental aspects of embryonic development?

<p>Cell division (A)</p> Signup and view all the answers

What does cholesterol promote in embryonic development?

<p>Morphogenesis (D)</p> Signup and view all the answers

Which type of plant product inhibits smoothened signaling in the sonic hedgehog (Shh) pathway?

<p>Cyclopamine (D)</p> Signup and view all the answers

What is the term for the ability of a cell to respond to morphogen signals?

<p>Cellular competence (C)</p> Signup and view all the answers

Which of the following results from defects in the sonic hedgehog (Shh) signaling pathway, as mentioned in the reading?

<p>Facial abnormalities (A)</p> Signup and view all the answers

What is involved in resolving the three progressive states of embryonic cells - specification, determination, and differentiation?

<p>Regulating gene expression (B)</p> Signup and view all the answers

What is the term for the mechanism by which cells 'know' their position along a line with respect to boundaries at either end?

<p>Positional information (C)</p> Signup and view all the answers

Which of the following is the process primarily involved in the generation of a new shape during development?

<p>Gastrulation (A)</p> Signup and view all the answers

What is the primary cell behavior that contributes to establishing an ordered body plan and specifying A/P, D/V axes?

<p>Cell proliferation (B)</p> Signup and view all the answers

What concept generally describes the ability of a cell to respond to inductive signals?

<p>Competence (A)</p> Signup and view all the answers

Which type of signal transmission involves the process by which adjacent cells receive and respond to the signal?

<p>Signal transduction (D)</p> Signup and view all the answers

Which stage involves cells being divided into specific germ layers, then into a specific subtype of cells within that germ layer, and eventually acquiring a unique fate?

<p>Differentiation (A)</p> Signup and view all the answers

What is the main type of cellular activity that serves to establish an ordered body plan and specify A/P, D/V axes?

<p>Cell proliferation (B)</p> Signup and view all the answers

What promotes the activity of smoothened signaling in the sonic hedgehog (Shh) pathway?

<p>Patched protein (Ptch) (C)</p> Signup and view all the answers

What does induction refer to in embryonic cell development?

<p>The ability of cells to influence the development of other cells using a signal (D)</p> Signup and view all the answers

What are three main types of signal transmission involved in embryonic cell development?

<p>Signal transduction, gene expression regulation, protein synthesis regulation (C)</p> Signup and view all the answers

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