Embryonic and Nervous System Development

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Questions and Answers

What is the initial stage of human development called, characterized as a single fertilized egg?

  • Zygote (correct)
  • Fetus
  • Embryo
  • Blastocyst

Which term describes the three-layered form of the blastocyst that prepares for organ development?

  • Gastrula (correct)
  • Zygote
  • Embryo
  • Fetus

What is the process of generating new neurons from progenitor cells known as?

  • Neurogenesis (correct)
  • Neuroplasticity
  • Gliogenesis
  • Neural migration

During neurogenesis, progenitor cells initially undergo which type of division?

<p>Symmetrical division (D)</p> Signup and view all the answers

Which structure provides a scaffold that guides the migration of newly formed neurons?

<p>Radial glia (C)</p> Signup and view all the answers

What is formed as a result of the first wave of neuron migration from the ventricular zone?

<p>Preplate zone (C)</p> Signup and view all the answers

At what week does the production of neuroblasts and glioblasts begin?

<p>7 weeks (D)</p> Signup and view all the answers

Which of the following layers is NOT one of the three germ layers formed during embryonic development?

<p>Neuroderm (A)</p> Signup and view all the answers

What is the primary distinction between sensation and perception?

<p>Sensation is the detection of a stimulus, and perception is the interpretation of that stimulus. (B)</p> Signup and view all the answers

What role do sensory receptors play in the process of sensation?

<p>They detect specific physical stimuli and facilitate the sensation process. (D)</p> Signup and view all the answers

Which of the following best represents the stages of sensation?

<p>Reception, transduction, coding. (D)</p> Signup and view all the answers

How is stimulus intensity encoded according to the information provided?

<p>Through the frequency of action potentials and specific active neurons. (D)</p> Signup and view all the answers

What is the purpose of lateral inhibition in sensory processing?

<p>To sharpen the perception of stimuli and enhance sensory acuity. (A)</p> Signup and view all the answers

Which statement accurately describes the organization of sensory inputs?

<p>Sensory systems are organized topographically corresponding to specific areas in the brain. (A)</p> Signup and view all the answers

What is the function of the thalamus in sensory processing?

<p>It relays most sensory information to appropriate cortical circuits. (B)</p> Signup and view all the answers

Which component of sensory receptors is NOT typically found among them?

<p>Receptor cells with direct axonal connections. (B)</p> Signup and view all the answers

What does the Doctrine of Specific Nerve Energies suggest about sensory perception?

<p>Different sensory inputs utilize distinct nerve energies leading to specific perceptions. (D)</p> Signup and view all the answers

What best describes tonic receptors in sensory adaptation?

<p>Maintain consistent responses to stimuli. (A)</p> Signup and view all the answers

Which pathway is responsible for transmitting epicritic touch sensations?

<p>Dorsal column-medial lemniscal pathway (B)</p> Signup and view all the answers

What role does the fovea play in human vision?

<p>Mediates high acuity and color vision. (D)</p> Signup and view all the answers

Which type of retinal ganglion cells is best suited for motion detection?

<p>Magnocellular cells (D)</p> Signup and view all the answers

What primarily separates epicritic touch from protopathic touch?

<p>Receptor types used (A)</p> Signup and view all the answers

Which theory explains the perception of colors through interactions of opposing color pairs?

<p>Opponent Process Theory (A)</p> Signup and view all the answers

What is the function of the primary visual cortex (PVC)?

<p>Processing visual information from the retina. (B)</p> Signup and view all the answers

How does phototransduction occur in photoreceptors?

<p>Chemical change initiates the visual process. (B)</p> Signup and view all the answers

What function does the dorsal stream primarily serve?

<p>Processing spatial awareness and motion. (B)</p> Signup and view all the answers

Which of the following receptors is primarily responsible for sensitive fine touch?

<p>Meissner corpuscles (C)</p> Signup and view all the answers

What do parvocellular circuits in the primary visual cortex primarily process?

<p>Color perception (C)</p> Signup and view all the answers

Which type of neuron helps enhance contrast in visual signals?

<p>Horizontal cells (C)</p> Signup and view all the answers

What is a characteristic of phasic receptors?

<p>Rapidly adapt to ongoing stimulation. (B)</p> Signup and view all the answers

What is the order of neuron layer formation in the cortical plate during development?

<p>Layers 1-6-5-4-3-2 (D)</p> Signup and view all the answers

What role does apoptosis play in neural development?

<p>It eliminates excess neurons. (C)</p> Signup and view all the answers

What is synaptogenesis primarily responsible for?

<p>Formation of synapses between neurons. (D)</p> Signup and view all the answers

What process describes the guidance of subsequent axons by pioneer growth cones?

<p>Fasciculation (D)</p> Signup and view all the answers

Which key developmental process begins around 24 weeks after conception?

<p>Myelination (B)</p> Signup and view all the answers

What effect can monocular deprivation have during a sensitive period for visual development?

<p>It disrupts ocular dominance columns. (D)</p> Signup and view all the answers

What influences the differentiation of neural crest cells during their migration?

<p>Chemical signals (A)</p> Signup and view all the answers

Which condition describes a common type of cognitive impairment that occurs with aging?

<p>Age-associated Memory Impairment (AAMI) (C)</p> Signup and view all the answers

What process is crucial for enhancing connectivity in the visual cortex through experience?

<p>Synaptic rearrangement (A)</p> Signup and view all the answers

What is the primary consequence of visual enrichment on brain development?

<p>Increased number of synapses (A)</p> Signup and view all the answers

What effect does chronic stress have on brain health?

<p>Leads to neurodegeneration (B)</p> Signup and view all the answers

What term describes the process of a neural plate forming and folding to create a neural tube?

<p>Neurulation (D)</p> Signup and view all the answers

Which mechanism involves the addition of methyl groups to DNA that impacts gene expression?

<p>DNA methylation (D)</p> Signup and view all the answers

Which of the following is NOT a key process involved in the development of the nervous system?

<p>Neuroplasticity (B)</p> Signup and view all the answers

Flashcards

Zygote

A fertilized egg, a single cell that rapidly divides.

Blastocyst

A hollow sphere of pluripotent cells that form the embryo.

Gastrula

A partially differentiated blastocyst with 3 germ layers (ectoderm, mesoderm, endoderm).

Neurogenesis

The process of creating new neurons from progenitor cells (like neural stem cells).

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Progenitor cells

Cells that give rise to neurons and other specialized cells.

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Migration

The movement of newly formed neurons to their designated locations in the brain, guided by radial glia.

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Radial Glia

Cells that act as guides for neuron migration during brain development.

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Embryonic Development

The process of an embryo forming into a fetus, involving distinct stages.

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Social odor recognition

The ability to recognize individuals based on their unique scent profiles, prevalent in many mammals, but not humans.

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Sensation

The detection of a stimulus and the recognition that an event has occurred. The process varies among different species.

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Perception

The interpretation and appreciation of sensory stimuli.

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Doctrine of Specific Nerve Energies

The idea that different sensory inputs to the brain utilize distinct nerve energies, resulting in specific perceptions. Each sensory system has specialized pathways.

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Sensory receptors

Specialized neurons that detect specific physical stimuli (light, sound, pressure). Most lack axons, but synapse with other neurons.

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Free nerve endings

A type of sensory receptor that is not encapsulated and detects pain and heat. Example: Nociceptors.

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Enclosed nerve endings

A type of sensory receptor that is encapsulated, such as Pacinian corpuscles, which detect touch.

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Specialized receptor cell

A type of sensory receptor that is highly specialized for a specific sense, such as auditory hair cells for hearing.

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Reception

The initial stage of sensation, where physical energy is absorbed by a sensory receptor.

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Transduction

The conversion of physical energy into an electrochemical pattern in neurons, allowing for signal transmission. The receptor 'talks' to the neuron.

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Inside-out Development

The process where the outermost layer of the cortex (layer I) forms first, followed by progressively deeper layers (II-VI), resulting in a six-layered structure.

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Tangential Migration

The movement of neurons along the surface of the developing cortex, contributing to the formation of subcortical neurons and interneurons.

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Cortical Dysplasia

A developmental disorder caused by disruptions in neuronal migration, leading to abnormal cortical structure and function.

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Differentiation

The process where neurons acquire specialized functions and identities, becoming distinct types of neurons or glia.

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Synaptogenesis

The formation of synapses between neurons, involving the growth of axons, dendrites, and synapses.

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Chemoaffinity

The process where growing axons are guided to their target destinations by chemical signals released from the postsynaptic target.

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Fasciculation

The process where pioneer growth cones guide subsequent axons, ensuring the formation of correct neural pathways.

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Apoptosis

Programmed cell death, a natural process that eliminates excess neurons during development.

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Synaptic Rearrangement

A fine-tuning process that refines neural connections, strengthening or eliminating synapses based on activity.

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Myelination

The process of forming a myelin sheath around axons, increasing the speed of electrical signal transmission between neurons.

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Neurulation

The process where the neural plate folds to form the neural tube, the precursor to the central nervous system (CNS).

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Rhombomeres

Segmented structures in the hindbrain during development, playing a role in organizing and patterning neural tissues.

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Sensory Placodes

Specialized regions of ectoderm that contribute to the development of sensory systems, like smell or taste.

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Environmental Enrichment

Conditions that provide sensory, social, and cognitive stimulation, leading to improved brain development.

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Environmental Impoverishment

Lack of stimulation that has negative impact on brain development, leading to reduced neural connectivity and cognitive deficits.

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Neuronal Assemblies

Groups of neurons that work together to encode information, especially intensity, by recruiting more neurons as the intensity increases.

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Intensity Encoding

The process of representing the strength of a stimulus using the number of active neurons.

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Frequency Encoding

Representing the frequency of a stimulus by the frequency of action potentials produced by neurons.

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Adaptation

The process of sensory receptors becoming less sensitive to a continuous stimulus over time.

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Tonic Receptors

Sensory receptors that respond continuously to a stimulus, slowly adapting or not adapting.

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Phasic Receptors

Sensory receptors that respond strongly at the onset of a stimulus but quickly adapt and decrease their response.

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Experience-Dependent Plasticity

The ability of the brain to change and adapt its structure and function based on experience.

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Somatosensation

The sense of touch, including pressure, temperature, pain, and proprioception.

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Epicritic Touch

The ability to feel fine details and discriminate between different textures.

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Protopathic Touch

The ability to feel non-discriminative sensations like pain and temperature.

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Pacinian Corpuscles

Encapsulated sensory receptors that respond to sudden, deep pressure.

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Meissner Corpuscles

Encapsulated sensory receptors that respond to sudden, light touch.

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Ruffini Corpuscles

Encapsulated sensory receptors that respond to gradual, stretch.

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Merkel's Disks

Encapsulated sensory receptors that respond to gradual, light touch.

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Proprioceptors

Sensory receptors that provide information about the position and movement of the body.

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Study Notes

Early Development

  • The initial stage of human development is the zygote, a single fertilized egg.
  • The gastrula, a three-layered form of the blastocyst, prepares for organ development.
  • Neurogenesis is the process of generating new neurons from progenitor cells.
  • During neurogenesis, progenitor cells initially undergo symmetrical division.
  • Radial glial cells provide a scaffold that guides the migration of newly formed neurons.
  • The cortical plate is formed as a result of the first wave of neuron migration from the ventricular zone.
  • The production of neuroblasts and glioblasts begins at week 6 of gestation.
  • The endoderm is not one of the three germ layers formed during embryonic development.

Sensory Processing

  • Sensation is the detection of physical stimuli, while perception is the interpretation of those stimuli.
  • Sensory receptors play a crucial role in sensation by converting physical stimuli into neural signals.
  • The stages of sensation include stimulus detection, transduction, and neural transmission.
  • Stimulus intensity is encoded by the frequency of action potentials generated in sensory neurons.
  • Lateral inhibition in sensory processing enhances contrast and sharpens perception by inhibiting neighboring neurons.
  • Sensory inputs are organized according to a hierarchical system, with more complex processing occurring at higher levels.
  • The thalamus serves as a relay station for sensory information before it reaches the cerebral cortex.
  • Interneurons are not typically found among sensory receptors.

Sensory Perception

  • The Doctrine of Specific Nerve Energies suggests that each sensory nerve transmits information about its specific modality.
  • Tonic receptors respond continuously to a stimulus throughout its duration.
  • The dorsal column–medial lemniscus pathway transmits epicritic touch sensations.
  • The fovea, a small region in the center of the retina, is responsible for sharp, detailed vision.
  • Magnocellular retinal ganglion cells are best suited for motion detection.
  • Epicritic touch differs from protopathic touch in terms of its finer discrimination and localization.
  • The opponent-process theory explains the perception of colors through interactions of opposing color pairs.

Vision

  • The primary visual cortex (PVC) is involved in the initial processing of visual information.
  • Phototransduction in photoreceptors occurs when light triggers a cascade of biochemical events, leading to a change in membrane potential.
  • The dorsal stream in the visual cortex primarily serves spatial processing and movement.
  • Merkel cells are primarily responsible for sensitive fine touch.

Visual Processing

  • Parvocellular circuits in the primary visual cortex primarily process color, shape, and texture.
  • Starburst amacrine cells help enhance contrast in visual signals.
  • Phasic receptors are rapidly adapting receptors that respond only to changes in stimulation.

Neural Development

  • The order of neuron layer formation in the cortical plate during development is inside-out, with deeper layers forming first.
  • Apoptosis, or programmed cell death, plays a crucial role in eliminating excess neurons.
  • Synaptogenesis is the process of forming new synapses between neurons.
  • Pioneer growth cones guide subsequent axons by laying down trails of signaling molecules.
  • Myelination, the process of forming myelin sheaths around axons, begins around 24 weeks after conception.
  • Monocular deprivation during a sensitive period for visual development can lead to reduced visual acuity in the deprived eye.
  • Environmental factors, such as the presence of specific signaling molecules, influence the differentiation of neural crest cells during their migration.

Aging and Brain Development

  • Mild cognitive impairment is a common type of cognitive impairment that occurs with aging.
  • Experience-dependent plasticity is a crucial process for enhancing connectivity in the visual cortex through experience.
  • Visual enrichment promotes brain development, leading to increased dendritic branching and synaptic density.
  • Chronic stress has a negative impact on brain health, impairing cognitive function and increasing vulnerability to neurodegenerative diseases.

Neural Development Processes

  • Neural tube formation, a crucial process in early development, involves the neural plate forming and folding to create a neural tube.
  • DNA methylation, the addition of methyl groups to DNA, influences gene expression and can impact neural development.
  • Cell migration, differentiation, and apoptosis are all key processes involved in the development of the nervous system.

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