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Questions and Answers
Which cells secrete metalloproteases (MMPs) in the early stages of Day 5-9?
Which cells secrete metalloproteases (MMPs) in the early stages of Day 5-9?
- Uterine epithelial cells
- Cytotrophoblasts (correct)
- Decidua cells
- Syncytiotrophoblasts
What happens to the cytotrophoblasts once they reach the decidua?
What happens to the cytotrophoblasts once they reach the decidua?
- They differentiate into syncytiotrophoblasts (correct)
- They lose their cell membranes
- They implant into the uterine epithelium
- They break down the material between the uterine epithelial cells
How can you distinguish between cytotrophoblasts and syncytiotrophoblasts?
How can you distinguish between cytotrophoblasts and syncytiotrophoblasts?
- Cytotrophoblasts lose their cell membranes (correct)
- Cytotrophoblasts are green cells
- Syncytiotrophoblasts are green cells
- Syncytiotrophoblasts break down material between uterine epithelial cells
What is the function of metalloproteases (MMPs) secreted by cytotrophoblasts?
What is the function of metalloproteases (MMPs) secreted by cytotrophoblasts?
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Study Notes
Early Stages of Embryonic Development
- Cytotrophoblasts secrete metalloproteases (MMPs) in the early stages of Day 5-9.
Cytotrophoblasts and Decidua
- Once cytotrophoblasts reach the decidua, they proliferate and differentiate into syncytiotrophoblasts.
Distinguishing between Cytotrophoblasts and Syncytiotrophoblasts
- Cytotrophoblasts are smaller, mononuclear cells with a high nuclear-to-cytoplasmic ratio, whereas syncytiotrophoblasts are larger, multinucleated cells with a low nuclear-to-cytoplasmic ratio.
Function of Metalloproteases (MMPs)
- Metalloproteases (MMPs) secreted by cytotrophoblasts facilitate implantation by breaking down the extracellular matrix, allowing the embryo to invade the decidua.
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