Podcast
Questions and Answers
What special chemicals are required to make the elixir stable?
What special chemicals are required to make the elixir stable?
What coloring agents are commonly used in elixirs?
What coloring agents are commonly used in elixirs?
What is the purpose of adding preservatives to elixirs?
What is the purpose of adding preservatives to elixirs?
Which vehicle can act as a preservative in oral liquid formulations?
Which vehicle can act as a preservative in oral liquid formulations?
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What is the advantage of pediatric drops as pharmaceutical products?
What is the advantage of pediatric drops as pharmaceutical products?
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Why are paediatric drops formulated as small dose volumes?
Why are paediatric drops formulated as small dose volumes?
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What is a common disadvantage of paediatric drops as pharmaceutical products?
What is a common disadvantage of paediatric drops as pharmaceutical products?
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How do drops differ from syrup in terms of concentration and total volume?
How do drops differ from syrup in terms of concentration and total volume?
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Why do drops require precise measuring devices for administration?
Why do drops require precise measuring devices for administration?
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What is the primary reason behind formulating drops with a high concentration of the drug per unit volume?
What is the primary reason behind formulating drops with a high concentration of the drug per unit volume?
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Study Notes
Elixir Formulation
- Parabens and antioxidants are special chemicals required to make the elixir stable.
Coloring Agents
- Commonly used coloring agents in elixirs include certified dyes, such as FD&C Red 40 and FD&C Yellow 6.
Preservatives in Elixirs
- The purpose of adding preservatives to elixirs is to prevent the growth of microorganisms and extend the product's shelf life.
- Glycerin can act as a preservative in oral liquid formulations, serving as a vehicle.
Pediatric Drops
- The advantage of pediatric drops as pharmaceutical products is their ease of administration, particularly for children and infants.
- Pediatric drops are formulated as small dose volumes to facilitate accurate dosing and minimize the risk of overdose.
- A common disadvantage of pediatric drops is the need for precise measurement and administration, which can be challenging for caregivers.
Drops vs. Syrup
- Drops differ from syrup in terms of concentration and total volume, with drops typically having a higher concentration of the drug per unit volume.
- The high concentration of the drug in drops requires precise measuring devices for administration to ensure accurate dosing.
Formulation of Drops
- The primary reason behind formulating drops with a high concentration of the drug per unit volume is to facilitate accurate dosing and minimize the volume of the formulation.
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Description
Explore the special chemicals like citric acid and disodium edetate used as stabilizers, coal tar dyes for coloring, and sweetening agents like sucrose syrup and fruit flavors in elixirs. Learn about the various additives that contribute to the stability, appearance, and taste of elixirs.
