Elevated Plus-Maze (EPM) Test Apparatus
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Questions and Answers

What is the primary purpose of the elevated plus-maze (EPM) test?

  • To measure the total distance traveled by rodents in a maze
  • To screen for antianxiety activity in a hole board apparatus
  • To evaluate anxiety-like behavior in rodents (correct)
  • To assess the curiosity of mice in a controlled environment

    • What is the significance of the open arms in the elevated plus-maze test?

  • They are used to measure the total distance traveled by rodents
  • They are used to assess the anxiety-like behavior in rodents (correct)
  • They are used to screen for antianxiety activity in a hole board apparatus
  • They are used to evaluate the curiosity of mice in a controlled environment

    • What is the critical assessment parameter of the hole board apparatus?

  • Time spent in the closed arms
  • Poking the nose into a hole (correct)
  • Total entries score
  • Total distance traveled

    • What is the size of the hole board apparatus?

    <p>40x40 cm</p> Signup and view all the answers

    How many holes are present in the platform of the hole board apparatus?

    <p>16 holes</p> Signup and view all the answers

    What is the diameter of each hole in the hole board apparatus?

    <p>3 cm</p> Signup and view all the answers

    What is the primary purpose of the forced swim test in animals?

    <p>To assess the development of an immobile posture in an inescapable environment</p> Signup and view all the answers

    What is the name of the chemical used to induce edema in the rat paw in the anti-inflammatory activity experiment?

    <p>Carrageenan (1% 0.1 ml sc)</p> Signup and view all the answers

    What is the parameter evaluated in the rat paw edema method?

    <p>The effectiveness of anti-inflammatory treatments</p> Signup and view all the answers

    What is the characteristic behavior observed in animals during the forced swim test?

    <p>Immobilization and floating</p> Signup and view all the answers

    What is the primary purpose of using carrageenan in the rat paw edema method?

    <p>To induce edema in rat paws for experimental purposes</p> Signup and view all the answers

    What is the environment used in the forced swim test?

    <p>A cylinder filled with water</p> Signup and view all the answers

    What is the primary purpose of the open field test?

    <p>To observe behavioral patterns of animals</p> Signup and view all the answers

    What is the typical duration of the open field test?

    <p>5 minutes</p> Signup and view all the answers

    Which of the following is NOT a behavioral pattern observed in the open field test?

    <p>Sleeping</p> Signup and view all the answers

    What is the name of the instrument used to screen antianxiety activity?

    <p>Open-field test</p> Signup and view all the answers

    What is the primary behavioral parameter observed in the forced swim test?

    <p>Swimming</p> Signup and view all the answers

    How many behavioral patterns are typically observed in the open field test?

    <p>6</p> Signup and view all the answers

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