Electron Transfer in Bioinorganic Chemistry

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Questions and Answers

What is the main class of chemical reactions involving net electron transfer in proteins?

  • Redox chemistry (correct)
  • Acid-base chemistry
  • Enzymatic catalysis
  • Oxygen-binding chemistry

Which metal center illustrates how bioinorganic chemistry uses acid-base chemistry?

  • Fens units
  • Porphyrin-bound iron (correct)
  • Cytochromes
  • Iron-sulfur clusters

What do bioinorganic current carriers usually do with their electrons?

  • Pass them to enzymes (correct)
  • Catalyze chemical reactions
  • Store them indefinitely
  • Use them for energy production

Which structure is widely encountered in bioinorganic chemistry and resembles the iron-porphyrin group used for dioxygen transport?

<p>Cytochromes (D)</p> Signup and view all the answers

What affects the metal potentials quoted for standard conditions in water?

<p>Biological ligands coordination (C)</p> Signup and view all the answers

What role do iron-sulfur clusters and cytochromes play in bioinorganic chemistry?

<p>Electron transfer centers (D)</p> Signup and view all the answers

What is the function of carbonic anhydrase?

<p>Promotes hydrolysis of CO2 (C)</p> Signup and view all the answers

Which metal ion is commonly found in the active site of many hydrolytic enzymes?

<p>Zn2+ (C)</p> Signup and view all the answers

What is the main function of alkaline phosphatase?

<p>Hydrolysis of phosphate esters (C)</p> Signup and view all the answers

Which metal ion is NOT commonly found in the active site of hydrolytic enzymes?

<p>Fe2+ (B)</p> Signup and view all the answers

What is the main function of dehydrogenases in metalloenzyme functions?

<p>Metal-nucleotide chemistry (B)</p> Signup and view all the answers

Why do hydrolytic enzymes often contain Zn2+ ions in their active sites?

<p>To avoid undesired electron-transfer chemistry (B)</p> Signup and view all the answers

What was the first metalloprotein to be discovered with Zn2+ ions?

<p>Transcription factor IIIA (TFIIIA) from the African clawed toad Xenopus (A)</p> Signup and view all the answers

In metalloenzymes, what term is used to describe the molecule being acted upon by the metalloenzyme?

<p>Substrate (C)</p> Signup and view all the answers

What is the role of Zn2+ ions in most DNA and RNA polymerases?

<p>Structural support (D)</p> Signup and view all the answers

Which bacterial protein regulates the expression of a mercury-detoxification system?

<p>MerR protein (A)</p> Signup and view all the answers

What is the general function of Hydrolytic Enzymes?

<p>Catalyzing addition or removal of water elements in a substrate (D)</p> Signup and view all the answers

What is the central role of Zn2+ ions in proteins containing zinc fingers?

<p>Forming the central core of small nucleic-acid-binding domains (A)</p> Signup and view all the answers

Which metal ion is present in most DNA and RNA polymerases?

<p>Zn2+ (C)</p> Signup and view all the answers

What type of gene regulation system depends on the presence or absence of bound metal ions?

<p>Metalloregulatory systems (B)</p> Signup and view all the answers

Which class of proteins involve Zn2+-stabilized domains directly interacting with DNA?

<p>Proteins typified by TFIIIA (C)</p> Signup and view all the answers

What do metalloenzymes do?

<p>Perform specific catalytic functions (D)</p> Signup and view all the answers

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