Electron Transfer in Bioinorganic Chemistry
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Questions and Answers

What is the main class of chemical reactions involving net electron transfer in proteins?

  • Redox chemistry (correct)
  • Acid-base chemistry
  • Enzymatic catalysis
  • Oxygen-binding chemistry
  • Which metal center illustrates how bioinorganic chemistry uses acid-base chemistry?

  • Fens units
  • Porphyrin-bound iron (correct)
  • Cytochromes
  • Iron-sulfur clusters
  • What do bioinorganic current carriers usually do with their electrons?

  • Pass them to enzymes (correct)
  • Catalyze chemical reactions
  • Store them indefinitely
  • Use them for energy production
  • Which structure is widely encountered in bioinorganic chemistry and resembles the iron-porphyrin group used for dioxygen transport?

    <p>Cytochromes</p> Signup and view all the answers

    What affects the metal potentials quoted for standard conditions in water?

    <p>Biological ligands coordination</p> Signup and view all the answers

    What role do iron-sulfur clusters and cytochromes play in bioinorganic chemistry?

    <p>Electron transfer centers</p> Signup and view all the answers

    What is the function of carbonic anhydrase?

    <p>Promotes hydrolysis of CO2</p> Signup and view all the answers

    Which metal ion is commonly found in the active site of many hydrolytic enzymes?

    <p>Zn2+</p> Signup and view all the answers

    What is the main function of alkaline phosphatase?

    <p>Hydrolysis of phosphate esters</p> Signup and view all the answers

    Which metal ion is NOT commonly found in the active site of hydrolytic enzymes?

    <p>Fe2+</p> Signup and view all the answers

    What is the main function of dehydrogenases in metalloenzyme functions?

    <p>Metal-nucleotide chemistry</p> Signup and view all the answers

    Why do hydrolytic enzymes often contain Zn2+ ions in their active sites?

    <p>To avoid undesired electron-transfer chemistry</p> Signup and view all the answers

    What was the first metalloprotein to be discovered with Zn2+ ions?

    <p>Transcription factor IIIA (TFIIIA) from the African clawed toad Xenopus</p> Signup and view all the answers

    In metalloenzymes, what term is used to describe the molecule being acted upon by the metalloenzyme?

    <p>Substrate</p> Signup and view all the answers

    What is the role of Zn2+ ions in most DNA and RNA polymerases?

    <p>Structural support</p> Signup and view all the answers

    Which bacterial protein regulates the expression of a mercury-detoxification system?

    <p>MerR protein</p> Signup and view all the answers

    What is the general function of Hydrolytic Enzymes?

    <p>Catalyzing addition or removal of water elements in a substrate</p> Signup and view all the answers

    What is the central role of Zn2+ ions in proteins containing zinc fingers?

    <p>Forming the central core of small nucleic-acid-binding domains</p> Signup and view all the answers

    Which metal ion is present in most DNA and RNA polymerases?

    <p>Zn2+</p> Signup and view all the answers

    What type of gene regulation system depends on the presence or absence of bound metal ions?

    <p>Metalloregulatory systems</p> Signup and view all the answers

    Which class of proteins involve Zn2+-stabilized domains directly interacting with DNA?

    <p>Proteins typified by TFIIIA</p> Signup and view all the answers

    What do metalloenzymes do?

    <p>Perform specific catalytic functions</p> Signup and view all the answers

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