Podcast
Questions and Answers
Which of the following is the primary rationale for electrically stimulating denervated muscle?
Which of the following is the primary rationale for electrically stimulating denervated muscle?
- To impede the regeneration of injured axons
- To facilitate functional recovery following reinnervation (correct)
- To accelerate the degeneration of neuromuscular junctions
- To prevent muscle atrophy
What is a physiological change that occurs in muscles following denervation?
What is a physiological change that occurs in muscles following denervation?
- Alteration in electrical properties of the membrane (correct)
- Increase in neuromuscular junctions integrity
- Decrease in subsarcolemmal nuclei
- Reduction in synthesis of the sarcoplasmic reticulum
What is a biochemical change that occurs in muscles following denervation?
What is a biochemical change that occurs in muscles following denervation?
- Decrease in synthesis of the sarcoplasm (correct)
- Transient decrease in the subsarcolemmal nuclei
- Reduction in lysosomes
- Increase in trophic substances supply from motoneurons
What change occurs in muscle contraction time following denervation?
What change occurs in muscle contraction time following denervation?
Prior to denervation, what maintains the physiologic integrity of muscle fibers?
Prior to denervation, what maintains the physiologic integrity of muscle fibers?
What is the rationale behind exercising denervated muscle?
What is the rationale behind exercising denervated muscle?
Which of the following is a potential benefit of electrical stimulation of denervated muscle?
Which of the following is a potential benefit of electrical stimulation of denervated muscle?
What is the most obvious change observed following denervation?
What is the most obvious change observed following denervation?
Why may intense stimuli (i.e., 25 mA) cause limited reinnervation in some studies?
Why may intense stimuli (i.e., 25 mA) cause limited reinnervation in some studies?
What happens if reinnervation has not occurred within 2 years following denervation?
What happens if reinnervation has not occurred within 2 years following denervation?
Why did many investigators and clinicians report that electrical stimulation only retarded the atrophy and did not prevent it?
Why did many investigators and clinicians report that electrical stimulation only retarded the atrophy and did not prevent it?
What is a possible reason for lack of success in facilitating reinnervation using electrical stimulation in some studies?
What is a possible reason for lack of success in facilitating reinnervation using electrical stimulation in some studies?
What may disrupt regenerating neuromuscular junctions and subsequently delay reinnervation?
What may disrupt regenerating neuromuscular junctions and subsequently delay reinnervation?
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