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V13_Electrical Impedance Spectroscopy in Microfluidic Systems

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18 Questions

What is the primary function of the electrodes in the microfluidic EIS sensor described in the text?

To measure the electrochemical impedance of the sample fluid

How does the electrical double layer at the electrolyte-electrode interface affect the electrochemical impedance measured by the EIS sensor?

The double layer capacitance varies with the composition of the sample fluid, leading to changes in the measured impedance

According to the Nernst equation, how does the reduction potential of an electrochemical reaction depend on the concentrations of the reactants and products?

The reduction potential is proportional to the natural logarithm of the ratio of product to reactant concentrations

How can the microfluidic EIS sensor be used in bioMEMS applications?

The sensor can be used to detect the presence of specific biomolecules in a sample fluid by monitoring changes in the electrochemical impedance

What is the purpose of the flow channel in the microfluidic EIS sensor?

To allow the sample fluid to flow over the electrodes, enabling real-time impedance measurements

How does the design of the microfluidic EIS sensor, with the electrodes embedded in the channel wall, affect the measurement of electrochemical impedance?

It increases the sensitivity of the sensor by maximizing the contact area between the electrodes and the sample fluid

What is the Poisson ratio of ZP material used in the context?

0.04

In Electrical Impedance Spectroscopy, what is the significance of a high Rhyd.2 compared to Rhyd.1?

Suggests higher charge transfer resistance

What is a drawback of Microscopic control in the context of microfluidic systems?

Bad contrast on transparent ZP

Which technique is suggested in the text for easy cell handling in EIS with µF?

Micropipette Aspiration Technique

What does a low resolution due to curved glass surfaces imply in EIS according to the text?

Observer-dependent readout method

In the context of Microfluidic Systems, what does 'bad contrast (transparent ZP)' suggest as a challenge?

Low resolution

What is the main function of microelectrodes in microfluidic systems related to temperature?

Heating and cooling

In the context of microelectrodes, what does the term 'passivation layer' refer to?

Layer to protect the electrode from unwanted reactions with the electrolyte

Which process involves the deposition of a metal layer in microelectrodes?

Electroplating

What is a common application of microelectrodes in bio-MEMS?

Recording nerve signals

How do microelectrodes contribute to the field of electrokinetics within microfluidic systems?

Manipulating particle movement through an electric field

What is one of the methods used to fabricate microelectrodes?

Lithography, Electroplating, photo resist strip

Explore the concept of Electrical Impedance Spectroscopy (EIS) in microfluidic systems, focusing on the Micropipette Aspiration Technique. Learn about observer-independent readout methods, cell handling techniques, and its multiplexing capability.

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