V13_Electrical Impedance Spectroscopy in Microfluidic Systems
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Questions and Answers

What is the primary function of the electrodes in the microfluidic EIS sensor described in the text?

  • To generate an electric field within the flow channel
  • To control the flow rate of the sample fluid
  • To provide a surface for the immobilization of biomolecules
  • To measure the electrochemical impedance of the sample fluid (correct)

    • How does the electrical double layer at the electrolyte-electrode interface affect the electrochemical impedance measured by the EIS sensor?

  • The double layer capacitance is negligible compared to the Faradaic impedance, so it has little effect on the overall impedance
  • The double layer capacitance dominates the overall impedance, making the sensor less sensitive to changes in the sample fluid
  • The double layer capacitance is constant, so it does not affect the measured impedance at all
  • The double layer capacitance varies with the composition of the sample fluid, leading to changes in the measured impedance (correct)

    • According to the Nernst equation, how does the reduction potential of an electrochemical reaction depend on the concentrations of the reactants and products?

  • The reduction potential is inversely proportional to the ratio of product to reactant concentrations
  • The reduction potential is directly proportional to the difference between the product and reactant concentrations
  • The reduction potential is independent of the concentrations of the reactants and products
  • The reduction potential is proportional to the natural logarithm of the ratio of product to reactant concentrations (correct)

    • How can the microfluidic EIS sensor be used in bioMEMS applications?

    <p>The sensor can be used to detect the presence of specific biomolecules in a sample fluid by monitoring changes in the electrochemical impedance</p> Signup and view all the answers

    What is the purpose of the flow channel in the microfluidic EIS sensor?

    <p>To allow the sample fluid to flow over the electrodes, enabling real-time impedance measurements</p> Signup and view all the answers

    How does the design of the microfluidic EIS sensor, with the electrodes embedded in the channel wall, affect the measurement of electrochemical impedance?

    <p>It increases the sensitivity of the sensor by maximizing the contact area between the electrodes and the sample fluid</p> Signup and view all the answers

    What is the Poisson ratio of ZP material used in the context?

    <p>0.04</p> Signup and view all the answers

    In Electrical Impedance Spectroscopy, what is the significance of a high Rhyd.2 compared to Rhyd.1?

    <p>Suggests higher charge transfer resistance</p> Signup and view all the answers

    What is a drawback of Microscopic control in the context of microfluidic systems?

    <p>Bad contrast on transparent ZP</p> Signup and view all the answers

    Which technique is suggested in the text for easy cell handling in EIS with µF?

    <p>Micropipette Aspiration Technique</p> Signup and view all the answers

    What does a low resolution due to curved glass surfaces imply in EIS according to the text?

    <p>Observer-dependent readout method</p> Signup and view all the answers

    In the context of Microfluidic Systems, what does 'bad contrast (transparent ZP)' suggest as a challenge?

    <p>Low resolution</p> Signup and view all the answers

    What is the main function of microelectrodes in microfluidic systems related to temperature?

    <p>Heating and cooling</p> Signup and view all the answers

    In the context of microelectrodes, what does the term 'passivation layer' refer to?

    <p>Layer to protect the electrode from unwanted reactions with the electrolyte</p> Signup and view all the answers

    Which process involves the deposition of a metal layer in microelectrodes?

    <p>Electroplating</p> Signup and view all the answers

    What is a common application of microelectrodes in bio-MEMS?

    <p>Recording nerve signals</p> Signup and view all the answers

    How do microelectrodes contribute to the field of electrokinetics within microfluidic systems?

    <p>Manipulating particle movement through an electric field</p> Signup and view all the answers

    What is one of the methods used to fabricate microelectrodes?

    <p>Lithography, Electroplating, photo resist strip</p> Signup and view all the answers

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