10 Questions
What is the name of the region on an antibody that will bind to the epitope?
Paratope
How many complementarity-determining regions (CDRs) form the paratope?
6
Which immunoglobulin class has a membrane-bound form as shown in the diagram (B)?
IgM
Which region of the antibody is responsible for most of the effector functions?
Fc
Which part of the antibody contains the portion required for antigen recognition?
Fab
What is the name of the enzyme that cleaves the antibody at the hinge region?
Papain
Which part of the light chain is included in the Fab region?
VL domain
Which immunoglobulin class is secreted, as shown in diagram (A)?
IgG
How many heavy chain constant domains are present in the Fc region?
2
Which part of the antibody tends to crystallize in solution?
Fc
Learn about the classification of human antibodies into five isotypes (IgG, IgA, IgM, IgD, and IgE) based on their heavy polypeptide chains, as well as the types of light chains (lambda and kappa) found in antibodies.
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