Effects of Pilocarpine on Exocrine Glands and Smooth Muscles

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Questions and Answers

What is a major reason why Acetylcholine (ACh) is not used clinically?

  • Effective orally
  • Limited spread effect
  • Long duration of action (correct)
  • Causes hypotension

Which choline ester is used for the treatment of postoperative and postpartum urinary retention?

  • Bethanechol (correct)
  • Atropine
  • Scopolamine
  • Methacholine

What is a common side effect observed with choline esters?

  • Increased heart rate
  • Bronchodilation
  • Nausea and vomiting (correct)
  • Hypertension

Why is Methacholine rarely used?

<p>Strong action on the cardiovascular system (D)</p> Signup and view all the answers

What is the main therapeutic use of Acetylcholine (ACh) when used topically to the eye?

<p>Induction of miosis preoperatively (A)</p> Signup and view all the answers

What is a contraindication for cholinergic agonists?

<p>Bronchial asthma (C)</p> Signup and view all the answers

What is the therapeutic use of choline esters?

<p>Management of glaucoma (A)</p> Signup and view all the answers

Which of the following is a therapeutic use of direct acting cholinergic agents?

<p>Relief of urinary retention (B)</p> Signup and view all the answers

For which condition are indirect acting parasympathomimetics commonly used?

<p>Myasthenia gravis (A)</p> Signup and view all the answers

What is a potential therapeutic effect of reversible cholinesterase inhibitors?

<p>Improved cognition (C)</p> Signup and view all the answers

Which condition is NOT commonly treated with direct acting cholinergic agents?

<p>Alzheimer's disease (C)</p> Signup and view all the answers

What is a potential side effect of using indirect acting parasympathomimetics?

<p>Constipation (B)</p> Signup and view all the answers

What is the therapeutic use of pilocarpine when administered orally?

<p>Treatment of xerostomia (C)</p> Signup and view all the answers

Which condition is NOT a therapeutic use of pilocarpine?

<p>Mydriatic effect of atropine (B)</p> Signup and view all the answers

What is the therapeutic use of cevimeline primarily related to?

<p>Sjogren's syndrome (C)</p> Signup and view all the answers

Which statement best describes the therapeutic effect of pilocarpine on exocrine glands?

<p>Increases salivary gland secretion (C)</p> Signup and view all the answers

In which condition would pilocarpine be least likely prescribed?

<p>Bronchospasm (A)</p> Signup and view all the answers

What distinguishes cevimeline from pilocarpine in terms of therapeutic use?

<p>Enhanced lacrimal secretions in xerostomia (D)</p> Signup and view all the answers

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