18 Questions
What is a major reason why Acetylcholine (ACh) is not used clinically?
Long duration of action
Which choline ester is used for the treatment of postoperative and postpartum urinary retention?
Bethanechol
What is a common side effect observed with choline esters?
Nausea and vomiting
Why is Methacholine rarely used?
Strong action on the cardiovascular system
What is the main therapeutic use of Acetylcholine (ACh) when used topically to the eye?
Induction of miosis preoperatively
What is a contraindication for cholinergic agonists?
Bronchial asthma
What is the therapeutic use of choline esters?
Management of glaucoma
Which of the following is a therapeutic use of direct acting cholinergic agents?
Relief of urinary retention
For which condition are indirect acting parasympathomimetics commonly used?
Myasthenia gravis
What is a potential therapeutic effect of reversible cholinesterase inhibitors?
Improved cognition
Which condition is NOT commonly treated with direct acting cholinergic agents?
Alzheimer's disease
What is a potential side effect of using indirect acting parasympathomimetics?
Constipation
What is the therapeutic use of pilocarpine when administered orally?
Treatment of xerostomia
Which condition is NOT a therapeutic use of pilocarpine?
Mydriatic effect of atropine
What is the therapeutic use of cevimeline primarily related to?
Sjogren's syndrome
Which statement best describes the therapeutic effect of pilocarpine on exocrine glands?
Increases salivary gland secretion
In which condition would pilocarpine be least likely prescribed?
Bronchospasm
What distinguishes cevimeline from pilocarpine in terms of therapeutic use?
Enhanced lacrimal secretions in xerostomia
Learn about the mechanism of action of pilocarpine and its effects on exocrine glands and smooth muscles. Explore how pilocarpine stimulates muscarinic receptors to trigger specific actions like increased secretion in exocrine glands and bronchospasm in bronchial smooth muscles.
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