41 Questions
matured rbc are nucleated
True
matured rbc has a biconvex shape
False
what is the diameter of rbc
8.5 micrometer
what is the edge thickness
2.5
what is the thickness
1.5 micrometer
There are about how much million /mm3 of blood with variation between the two sexes?
5
male is about what
4.6 to 6
female is about
4.3 to 4.5
the variation in rbc is due to what
gonadal hormone testosterone in male which is an rbc differentiation inducer , greater mass musculature in male requires more oxygen supply
tell me about the shape of rbc
it creates maximum surface area for small volume of the cell and large diffusion surface for passage of gasses
tell me more about the shape of the rbc
it allows fir squeezing of rbc when passing through narrow vessels wirhout damage to the integrity if the cell
is present on the membrane helping to utilize glucoce,O2 and ATP
Glucose-6phosphate dehydrogenase
what is the life span for rbc?
120 days
the count is higher in new borns than in adults
True
what is the count in new borns
6 m
its production is stimulated by what
hypoxia
release if erythropoetin as a redult of hypoxia is how nany percentage in kidney
85%
from liver is how many %
15%
erythropoetin is a what
glycoprotein
Contains 165 aa residues & 4oligosaccharide chains
True
it is a differentiation inducer
True
half life is what in erythropoetin
5hours
apart from hypoxia , what other thing is the epo stimulated by
colbat and androgens
principal site of inactivaton of epo
liver
whats affects epo production
chronic renal disease
The gene is cloned and recombinant EPO is available for clinical use
True
rbc is existing in an isotonic environment
True
changed in stability afftects the stability and what of rbc?
volume
at what salinity is rbc isotonic with plasma
0.9
when does lysis begin
0.5
0.4 to 0.42 saline lysis is what
50%
when is saline lysis 100%
0.35
buffy coat , what is that
white cell that settle at the top of a testube after centrifuge
what is hematocrit
fraction occupied by the rbc
what is the hemato crit in male and female and also averagely
47% , 42%, 45
what is erythrocyte sedimentation rate
rate of settlement if rbc without being centrifuged
what does erythrocyte sefimentation rate depend on
shape of the cell and concentration of plasna protein and infection
what is roulex formation
the stacking of rbc on each other
uses if erythrocyte sedimentstion rate rate
monitoring recovering from disease or efficiency of treatment
it varies with what
age and sex
it varies with what
age and sex
erythrocyte
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