Early Onset Epilepsy in Children

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Questions and Answers

What percentage of early onset epilepsy cases are believed to have a genetic cause?

  • 50% (correct)
  • 90%
  • 25%
  • 75%

During which stage of life is the brain most malleable?

  • Old age
  • Adolescence
  • Adulthood
  • Childhood (correct)

What is the estimated risk of sudden unexpected death in epilepsy (SUDEP)?

  • 0.05% - 0.1%
  • 0.5% - 1%
  • 0.1% - 0.2% (correct)
  • 1% - 2%

What is a result of recurrent epileptic brain activity during childhood?

<p>Permanent changes to the brain's shape (D)</p> Signup and view all the answers

Why do children have an advantage over adults with epilepsy surgery?

<p>Their brains are more malleable (D)</p> Signup and view all the answers

In epilepsy, what happens to the electrical signals in the brain?

<p>They become scrambled and sometimes burst with activity (B)</p> Signup and view all the answers

What is the possible genetic link to epilepsy?

<p>1 in 3 people with epilepsy have a family member with it (D)</p> Signup and view all the answers

What is a common trigger for seizures in people with epilepsy?

<p>Lack of sleep (B)</p> Signup and view all the answers

What is the main symptom of epilepsy?

<p>Repeated seizures (D)</p> Signup and view all the answers

What type of seizure affects only one hemisphere of the brain?

<p>Focal aware seizure (B)</p> Signup and view all the answers

What is the term for uncontrollable jerking and shaking during a seizure?

<p>Fit (C)</p> Signup and view all the answers

What is the name of the professional organization that establishes the terminology and approaches for classifying seizures and forms of epilepsy?

<p>International League Against Epilepsy (A)</p> Signup and view all the answers

What is the framework used by healthcare professionals to diagnose and treat patients with epilepsy?

<p>Classification of the Epilepsies (C)</p> Signup and view all the answers

What is taken into account when classifying seizures under the new system?

<p>Seizure onset, additional features, and expanded classification (D)</p> Signup and view all the answers

What is the term for a seizure that involves the entire brain?

<p>Generalized seizure (D)</p> Signup and view all the answers

What is the term for a seizure that has no physical component?

<p>Absence seizure (D)</p> Signup and view all the answers

What is the common term for simple focal seizures?

<p>Auras (D)</p> Signup and view all the answers

What is the duration of a myoclonic seizure?

<p>A fraction of a second (A)</p> Signup and view all the answers

What is the term for a seizure that lasts a long time or a series of seizures where the person does not regain consciousness in between?

<p>Status epilepticus (C)</p> Signup and view all the answers

What is the purpose of an EEG?

<p>To check for unusual electrical activity in the brain (A)</p> Signup and view all the answers

What happens to the muscles during an atonic seizure?

<p>They suddenly relax (A)</p> Signup and view all the answers

What happens to the person's consciousness during a complex focal seizure?

<p>They lose the sense of awareness (B)</p> Signup and view all the answers

What is the term for a seizure that affects children mainly, but can happen at any age?

<p>Absence seizure (C)</p> Signup and view all the answers

What is the purpose of an MRI scan in diagnosing epilepsy?

<p>To spot problems in the brain that can sometimes cause epilepsy (B)</p> Signup and view all the answers

What happens to the person's bladder or bowel control during a tonic-clonic seizure?

<p>They lose control of the bladder or bowel (B)</p> Signup and view all the answers

What is the duration of the clonic stage of a tonic-clonic seizure?

<p>A few minutes (A)</p> Signup and view all the answers

What is the risk associated with the use of phenobarbital and topiramate during pregnancy?

<p>Both neurodevelopmental toxicity and increased risk of intra-uterine growth restriction (C)</p> Signup and view all the answers

What is the recommended duration for reducing dosage when withdrawing antiepileptic drugs?

<p>At least three months (B)</p> Signup and view all the answers

What should be done if seizures recur during or after discontinuation of an antiepileptic drug?

<p>Reverse the last dose reduction and seek guidance from an epilepsy specialist (B)</p> Signup and view all the answers

Why is it recommended to withdraw only one antiepileptic drug at a time in patients receiving multiple drugs?

<p>To minimize the risk of seizure recurrence (D)</p> Signup and view all the answers

What is the recommended duration for withdrawing barbiturates and benzodiazepines?

<p>Over a longer period than other antiepileptic drugs (B)</p> Signup and view all the answers

What should be done before considering the withdrawal of antiepileptic drugs from a seizure-free patient?

<p>Assess the risk of seizure recurrence (B)</p> Signup and view all the answers

What is the treatment used to control seizures by changing the electrical signals in the brain?

<p>Vagus Nerve Stimulation (VNS) (A)</p> Signup and view all the answers

Which medication is a Sodium Channel Blocker?

<p>Carbamazepine (C)</p> Signup and view all the answers

What is the name of the nerve that is stimulated in Vagus Nerve Stimulation (VNS)?

<p>Vagus Nerve (C)</p> Signup and view all the answers

What is the term for medications that increase GABA?

<p>GABA Modulators (D)</p> Signup and view all the answers

Which medication is not recommended for females who are able to have children?

<p>Sodium Valproate (B)</p> Signup and view all the answers

What is the purpose of Deep Brain Stimulation (DBS)?

<p>To change the electrical signals in the brain (B)</p> Signup and view all the answers

What is the term for the diet that is used to help manage epilepsy?

<p>Ketogenic Diet (D)</p> Signup and view all the answers

Which medication is a Calcium Channel Blocker?

<p>Gabapentin (A)</p> Signup and view all the answers

What is the purpose of Brain Surgery?

<p>To remove part of the brain (B)</p> Signup and view all the answers

Which of the following can exacerbate absence or myoclonic seizures?

<p>All of the above (D)</p> Signup and view all the answers

What is the first-line treatment for absence seizures?

<p>Ethosuximide (D)</p> Signup and view all the answers

Which of the following medications should be avoided in patients with myoclonic seizures?

<p>Phenobarbital (B)</p> Signup and view all the answers

What is the recommended treatment for atonic or tonic seizures in females who are able to have children?

<p>Lamotrigine (A)</p> Signup and view all the answers

What is the estimated risk of congenital malformations associated with valproate use during pregnancy?

<p>10% (C)</p> Signup and view all the answers

According to the MHRA/CHM advice, what is the risk of neurodevelopmental disorders associated with valproate use during pregnancy?

<p>30-40% (A)</p> Signup and view all the answers

Which of the following medications is not associated with an increased risk of major congenital malformations?

<p>Lamotrigine (D)</p> Signup and view all the answers

What is the recommended treatment for absence seizures if ethosuximide is unsuccessful?

<p>Sodium valproate (B)</p> Signup and view all the answers

Which of the following medications is highly teratogenic and should not be used in females of childbearing potential?

<p>Valproate (A)</p> Signup and view all the answers

What is the recommended treatment for myoclonic seizures in females who are able to have children?

<p>Levetiracetam (C)</p> Signup and view all the answers

What is the recommended treatment for atonic or tonic seizures if lamotrigine is unsuccessful?

<p>All of the above (D)</p> Signup and view all the answers

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