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Early Breast Cancer Diagnosis and Treatment

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Early Breast Cancer Diagnosis and Treatment

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Questions and Answers

What is the primary categorization of early breast cancer?

Stage I and Stage II breast cancer
Invasive and non-invasive carcinoma
Benign and malignant tumours
Invasive carcinoma and ductal carcinoma in situ (correct)

What is the primary goal of breast-conserving surgery in treating early breast cancer?

To diagnose the type of breast cancer
To perform adjuvant radiotherapy
To achieve a tumour-free margin (correct)
To remove the entire breast

What is the implication of having a positive margin following breast-conserving surgery?

A higher incidence of ipsilateral breast tumour recurrence (correct)
A higher incidence of contralateral breast tumour recurrence
A lower incidence of ipsilateral breast tumour recurrence
No effect on ipsilateral breast tumour recurrence

What is the significance of a negative margin in invasive breast carcinoma?

It is adequate for breast-conserving surgery (D) Signup and view all the answers

What is the relationship between negative margins and local recurrence rate in ductal carcinoma in situ?

Larger negative margins are associated with a lower local recurrence rate (A) Signup and view all the answers

What is the purpose of adjuvant radiotherapy following breast-conserving surgery?

To provide effective local treatment (D) Signup and view all the answers

What is the primary finding of a meta-analysis involving 33 studies on stage I and II invasive breast carcinoma?

A two-fold increase in ipsilateral breast tumour recurrence with positive margins (B) Signup and view all the answers

What is the implication of having a negative margin wider than 'no ink on tumour' in invasive breast carcinoma?

It is not associated with a lower incidence of ipsilateral breast tumour recurrence (D) Signup and view all the answers

What is the primary reason for performing breast-conserving surgery in early breast cancer?

To remove the tumour with adequate tumour-free margin (D) Signup and view all the answers

What is the significance of 'no ink on tumour' in breast-conserving surgery?

It indicates a negative margin (B) Signup and view all the answers

In which type of breast cancer is a negative margin significantly associated with a lower local recurrence rate?

Ductal carcinoma in situ (A) Signup and view all the answers

What is the effect of a positive margin on ipsilateral breast tumour recurrence in stage I and II invasive breast carcinoma?

It increases the risk of recurrence by two-fold (C) Signup and view all the answers

What is the role of adjuvant radiotherapy in treating early breast cancer?

It is used in conjunction with breast-conserving surgery to reduce the risk of local recurrence (B) Signup and view all the answers

What is the primary difference between invasive carcinoma and ductal carcinoma in situ?

One has invaded surrounding tissues, while the other is contained in the milk ducts (D) Signup and view all the answers

What is the purpose of a meta-analysis involving 33 studies on stage I and II invasive breast carcinoma?

To study the association between margin status and ipsilateral breast tumour recurrence (A) Signup and view all the answers

What is the recommended treatment for early breast cancer?

Breast-conserving surgery with negative margin followed by adjuvant radiotherapy (D) Signup and view all the answers