16 Questions
What is the primary categorization of early breast cancer?
Invasive carcinoma and ductal carcinoma in situ
What is the primary goal of breast-conserving surgery in treating early breast cancer?
To achieve a tumour-free margin
What is the implication of having a positive margin following breast-conserving surgery?
A higher incidence of ipsilateral breast tumour recurrence
What is the significance of a negative margin in invasive breast carcinoma?
It is adequate for breast-conserving surgery
What is the relationship between negative margins and local recurrence rate in ductal carcinoma in situ?
Larger negative margins are associated with a lower local recurrence rate
What is the purpose of adjuvant radiotherapy following breast-conserving surgery?
To provide effective local treatment
What is the primary finding of a meta-analysis involving 33 studies on stage I and II invasive breast carcinoma?
A two-fold increase in ipsilateral breast tumour recurrence with positive margins
What is the implication of having a negative margin wider than 'no ink on tumour' in invasive breast carcinoma?
It is not associated with a lower incidence of ipsilateral breast tumour recurrence
What is the primary reason for performing breast-conserving surgery in early breast cancer?
To remove the tumour with adequate tumour-free margin
What is the significance of 'no ink on tumour' in breast-conserving surgery?
It indicates a negative margin
In which type of breast cancer is a negative margin significantly associated with a lower local recurrence rate?
Ductal carcinoma in situ
What is the effect of a positive margin on ipsilateral breast tumour recurrence in stage I and II invasive breast carcinoma?
It increases the risk of recurrence by two-fold
What is the role of adjuvant radiotherapy in treating early breast cancer?
It is used in conjunction with breast-conserving surgery to reduce the risk of local recurrence
What is the primary difference between invasive carcinoma and ductal carcinoma in situ?
One has invaded surrounding tissues, while the other is contained in the milk ducts
What is the purpose of a meta-analysis involving 33 studies on stage I and II invasive breast carcinoma?
To study the association between margin status and ipsilateral breast tumour recurrence
What is the recommended treatment for early breast cancer?
Breast-conserving surgery with negative margin followed by adjuvant radiotherapy
This quiz covers the classification and treatment of early breast cancer, including invasive carcinoma and ductal carcinoma in situ. It also discusses the role of breast-conserving surgery and radiotherapy in treating early breast cancer.
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