Early Breast Cancer Diagnosis and Treatment
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Questions and Answers

What is the primary categorization of early breast cancer?

  • Stage I and Stage II breast cancer
  • Invasive and non-invasive carcinoma
  • Benign and malignant tumours
  • Invasive carcinoma and ductal carcinoma in situ (correct)
  • What is the primary goal of breast-conserving surgery in treating early breast cancer?

  • To diagnose the type of breast cancer
  • To perform adjuvant radiotherapy
  • To achieve a tumour-free margin (correct)
  • To remove the entire breast
  • What is the implication of having a positive margin following breast-conserving surgery?

  • A higher incidence of ipsilateral breast tumour recurrence (correct)
  • A higher incidence of contralateral breast tumour recurrence
  • A lower incidence of ipsilateral breast tumour recurrence
  • No effect on ipsilateral breast tumour recurrence
  • What is the significance of a negative margin in invasive breast carcinoma?

    <p>It is adequate for breast-conserving surgery</p> Signup and view all the answers

    What is the relationship between negative margins and local recurrence rate in ductal carcinoma in situ?

    <p>Larger negative margins are associated with a lower local recurrence rate</p> Signup and view all the answers

    What is the purpose of adjuvant radiotherapy following breast-conserving surgery?

    <p>To provide effective local treatment</p> Signup and view all the answers

    What is the primary finding of a meta-analysis involving 33 studies on stage I and II invasive breast carcinoma?

    <p>A two-fold increase in ipsilateral breast tumour recurrence with positive margins</p> Signup and view all the answers

    What is the implication of having a negative margin wider than 'no ink on tumour' in invasive breast carcinoma?

    <p>It is not associated with a lower incidence of ipsilateral breast tumour recurrence</p> Signup and view all the answers

    What is the primary reason for performing breast-conserving surgery in early breast cancer?

    <p>To remove the tumour with adequate tumour-free margin</p> Signup and view all the answers

    What is the significance of 'no ink on tumour' in breast-conserving surgery?

    <p>It indicates a negative margin</p> Signup and view all the answers

    In which type of breast cancer is a negative margin significantly associated with a lower local recurrence rate?

    <p>Ductal carcinoma in situ</p> Signup and view all the answers

    What is the effect of a positive margin on ipsilateral breast tumour recurrence in stage I and II invasive breast carcinoma?

    <p>It increases the risk of recurrence by two-fold</p> Signup and view all the answers

    What is the role of adjuvant radiotherapy in treating early breast cancer?

    <p>It is used in conjunction with breast-conserving surgery to reduce the risk of local recurrence</p> Signup and view all the answers

    What is the primary difference between invasive carcinoma and ductal carcinoma in situ?

    <p>One has invaded surrounding tissues, while the other is contained in the milk ducts</p> Signup and view all the answers

    What is the purpose of a meta-analysis involving 33 studies on stage I and II invasive breast carcinoma?

    <p>To study the association between margin status and ipsilateral breast tumour recurrence</p> Signup and view all the answers

    What is the recommended treatment for early breast cancer?

    <p>Breast-conserving surgery with negative margin followed by adjuvant radiotherapy</p> Signup and view all the answers

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