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Questions and Answers
What is the primary effect of Ezetimibe?
What is the primary effect of Ezetimibe?
- Significant reduction in HDL-C
- Modest reduction in LDL-C (correct)
- Marked increase in triglycerides
- Elevation of ALT levels
What is the mechanism by which Bile Acid Sequestrants reduce LDL-C levels?
What is the mechanism by which Bile Acid Sequestrants reduce LDL-C levels?
- By inhibiting the NPC1L1 protein
- By binding bile acids in the intestinal lumen (correct)
- By stimulating hepatic synthesis of cholesterol
- By reducing the absorption of dietary cholesterol
What is the range of LDL-C reduction achievable with Ezetimibe monotherapy?
What is the range of LDL-C reduction achievable with Ezetimibe monotherapy?
- 5%–10%
- 25%–30%
- 15%–24% (correct)
- 35%–40%
What is the benefit of combining Ezetimibe with statin therapy?
What is the benefit of combining Ezetimibe with statin therapy?
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Why are Bile Acid Sequestrants considered first-line therapy during pregnancy?
Why are Bile Acid Sequestrants considered first-line therapy during pregnancy?
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What is the mechanism by which Ezetimibe reduces LDL-C levels?
What is the mechanism by which Ezetimibe reduces LDL-C levels?
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What is a common side effect of Ezetimibe?
What is a common side effect of Ezetimibe?
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What is the range of LDL-C reduction achievable with Bile Acid Sequestrants?
What is the range of LDL-C reduction achievable with Bile Acid Sequestrants?
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What is the effect of Bile Acid Sequestrants on hepatic synthesis of bile acids?
What is the effect of Bile Acid Sequestrants on hepatic synthesis of bile acids?
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What is the effect of Bile Acid Sequestrants on the number of LDL receptors on hepatocyte membranes?
What is the effect of Bile Acid Sequestrants on the number of LDL receptors on hepatocyte membranes?
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