Drugs with Special Cautions in the Elderly

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18 Questions

What is a potential concern with long-term use of non-selective NSAIDs in the elderly?

Increased risk of renal failure, GI bleeding, hypertension, and heart failure

Which of the following medications is associated with QT prolongation and torsades de pointes?

Disopyramide

Which of the following medications can produce insomnia and agitation in the elderly?

Fluoxetine

What is a concern with using anticholinergic medications in elderly patients?

Potential to cause confusion and sedation

Why is it essential to consider drug formulation when prescribing for elderly patients?

To ensure convenient administration and adherence

What is a general rule of prescribing for elderly patients?

Do not give unnecessary drugs

What is the effect of antimuscarinic drugs on the heart in elderly individuals?

Decreased action due to attenuation of its parasympathetic innervation

Why are sedative-hypnotic drugs more likely to depress respiration in elderly individuals?

Due to decreased pulmonary function

What is the effect of β-adrenoceptor agonists and antagonists in elderly individuals?

Blunted response

What is the effect of prazosin and chlorpromazine on blood pressure in elderly individuals?

Decrease blood pressure

Why are elderly individuals more prone to drug-induced depression?

Due to polypharmacy

What is the effect of anticholinergic drugs on elderly individuals?

All of the above

What is a safety concern with the use of methyldopa in the elderly?

It exacerbates depression

Why are other NSAIDs preferred over indomethacin in the elderly?

They cause fewer CNS toxic reactions

Why is thioridazine considered a less desirable option in the elderly?

It has a greater potential for CNS and extrapyramidal side effects

What is a concern with the use of nitrofurantoin in the elderly?

It has a potential for renal impairment

Why is orphenadrine considered a less desirable option in the elderly?

It causes more sedation and anticholinergic effects

What is a concern with the use of diphenhydramine in the elderly?

It causes confusion and sedation

Learn about the anticholinergic and antihistamine drugs that require special caution when prescribed to elderly patients, including their effects and alternative treatments. Test your knowledge of these medications and their implications for elderly care.

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