18 Questions
What is a potential concern with long-term use of non-selective NSAIDs in the elderly?
Increased risk of renal failure, GI bleeding, hypertension, and heart failure
Which of the following medications is associated with QT prolongation and torsades de pointes?
Disopyramide
Which of the following medications can produce insomnia and agitation in the elderly?
Fluoxetine
What is a concern with using anticholinergic medications in elderly patients?
Potential to cause confusion and sedation
Why is it essential to consider drug formulation when prescribing for elderly patients?
To ensure convenient administration and adherence
What is a general rule of prescribing for elderly patients?
Do not give unnecessary drugs
What is the effect of antimuscarinic drugs on the heart in elderly individuals?
Decreased action due to attenuation of its parasympathetic innervation
Why are sedative-hypnotic drugs more likely to depress respiration in elderly individuals?
Due to decreased pulmonary function
What is the effect of β-adrenoceptor agonists and antagonists in elderly individuals?
Blunted response
What is the effect of prazosin and chlorpromazine on blood pressure in elderly individuals?
Decrease blood pressure
Why are elderly individuals more prone to drug-induced depression?
Due to polypharmacy
What is the effect of anticholinergic drugs on elderly individuals?
All of the above
What is a safety concern with the use of methyldopa in the elderly?
It exacerbates depression
Why are other NSAIDs preferred over indomethacin in the elderly?
They cause fewer CNS toxic reactions
Why is thioridazine considered a less desirable option in the elderly?
It has a greater potential for CNS and extrapyramidal side effects
What is a concern with the use of nitrofurantoin in the elderly?
It has a potential for renal impairment
Why is orphenadrine considered a less desirable option in the elderly?
It causes more sedation and anticholinergic effects
What is a concern with the use of diphenhydramine in the elderly?
It causes confusion and sedation
Learn about the anticholinergic and antihistamine drugs that require special caution when prescribed to elderly patients, including their effects and alternative treatments. Test your knowledge of these medications and their implications for elderly care.
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