Drugs with Special Cautions in the Elderly

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Questions and Answers

What is a potential concern with long-term use of non-selective NSAIDs in the elderly?

  • Increased risk of renal failure, GI bleeding, hypertension, and heart failure (correct)
  • Worsening of depression
  • Development of insomnia
  • Risk of allergic reactions

Which of the following medications is associated with QT prolongation and torsades de pointes?

  • Cyproheptadine
  • Chlorpheniramine
  • Disopyramide (correct)
  • Dicyclomine

Which of the following medications can produce insomnia and agitation in the elderly?

  • Promethazine
  • Fluoxetine (correct)
  • Diphenhydramine
  • Cyproheptadine

What is a concern with using anticholinergic medications in elderly patients?

<p>Potential to cause confusion and sedation (C)</p> Signup and view all the answers

Why is it essential to consider drug formulation when prescribing for elderly patients?

<p>To ensure convenient administration and adherence (D)</p> Signup and view all the answers

What is a general rule of prescribing for elderly patients?

<p>Do not give unnecessary drugs (C)</p> Signup and view all the answers

What is the effect of antimuscarinic drugs on the heart in elderly individuals?

<p>Decreased action due to attenuation of its parasympathetic innervation (C)</p> Signup and view all the answers

Why are sedative-hypnotic drugs more likely to depress respiration in elderly individuals?

<p>Due to decreased pulmonary function (C)</p> Signup and view all the answers

What is the effect of β-adrenoceptor agonists and antagonists in elderly individuals?

<p>Blunted response (A)</p> Signup and view all the answers

What is the effect of prazosin and chlorpromazine on blood pressure in elderly individuals?

<p>Decrease blood pressure (A)</p> Signup and view all the answers

Why are elderly individuals more prone to drug-induced depression?

<p>Due to polypharmacy (A)</p> Signup and view all the answers

What is the effect of anticholinergic drugs on elderly individuals?

<p>All of the above (D)</p> Signup and view all the answers

What is a safety concern with the use of methyldopa in the elderly?

<p>It exacerbates depression (B)</p> Signup and view all the answers

Why are other NSAIDs preferred over indomethacin in the elderly?

<p>They cause fewer CNS toxic reactions (B)</p> Signup and view all the answers

Why is thioridazine considered a less desirable option in the elderly?

<p>It has a greater potential for CNS and extrapyramidal side effects (D)</p> Signup and view all the answers

What is a concern with the use of nitrofurantoin in the elderly?

<p>It has a potential for renal impairment (D)</p> Signup and view all the answers

Why is orphenadrine considered a less desirable option in the elderly?

<p>It causes more sedation and anticholinergic effects (D)</p> Signup and view all the answers

What is a concern with the use of diphenhydramine in the elderly?

<p>It causes confusion and sedation (A)</p> Signup and view all the answers

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