Drugs for Coagulation Disorders

Conditions where the normal blood clotting mechanism is disrupted, leading to excessive bleeding or clotting.

Damage to the lining of a blood vessel, triggering the clotting process.

Narrowing of blood vessels to reduce blood loss.

Platelets clump together to form a temporary plug at the injury site.

Small blood cells crucial for forming blood clots.

The process where a blood clot is formed to permanently stop bleeding.

A fibrous protein that plays a central role in platelet plug formation.

Series of reactions that result in the formation of a stable blood clot.

The normal process of stopping bleeding, disrupted in coagulation disorders.

The inner layer of a blood vessel that is damaged in injury.

A glycoprotein essential for platelet function and blood clotting.

A protein that forms the meshwork of a blood clot.

Vasoconstriction, Platelet plug formation, and Blood coagulation are the 3 crucial and sequential stages.

A temporary clot formed from aggregated platelets

A permanent blood clot formed from fibrin.

The enzymatic process of breaking down a fibrin clot to reduce its size and spread.

An enzyme that breaks down fibrin, helping to dissolve blood clots.

Tissue Plasminogen Activator, an enzyme that activates plasminogen, leading to clot breakdown.

A small protein that acts as an anticoagulant, neutralizing active clotting factors.

A series of reactions in the blood that leads to the formation of a blood clot.

A medical condition involving blood clots (thrombi), especially deep vein thrombosis and pulmonary embolism.

A blood clot that forms in a deep vein, often in the legs.

A blood clot that travels to the lungs and blocks blood flow.

Drugs that prevent or reduce blood clotting.

Drugs that prevent platelets from clumping together to form clots.

Drugs that dissolve blood clots.

Treatment aimed at preventing blood clot formation while minimizing bleeding risk.

A class of anticoagulants that specifically target and inhibit the action of the enzyme thrombin.

Blood clots that develop within the blood vessels.

A heart rhythm problem where the atria (upper chambers) beat irregularly causing increased risk of blood clots.

Blood clots formed in the veins.

An anticoagulant drug used to prevent blood clots.

Preventing a disease/undesired condition or injury before it happens, in this context to prevent thrombi.

Events caused by blood clots, including heart attacks or strokes.

Clumping together of platelets to form a clot.

Drugs that stop platelets from clumping and forming blood clots.

Drugs that block the enzyme COX-1, reducing thromboxane A2 (TXA2) production and thus reducing platelet aggregation.

Drugs that block ADP receptors on platelets, reducing platelet activation and aggregation.

Drugs that block receptors on platelets to inhibit their aggregation.

Drugs that break up existing blood clots.

Vitamin used for blood clotting and as a cofactor in clotting factor synthesis

A bleeding disorder caused by missing clotting factors.

A protein that becomes plasmin to break down blood clots.

An enzyme that converts plasminogen to plasmin, thus breaking down fibrin clots.