Drugs for Anemia and Hematological Disorders
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Questions and Answers

What is the most commonly implicated aetiological agent in acquired Fanconi's anaemia?

  • Bacterial infection
  • Chemical
  • Drug (correct)
  • Virus

    • Which type of drugs can predictably cause aplastic anaemia if given in sufficient doses?

  • Antibiotics
  • NSAIDs
  • Alkylating agents (correct)
  • Antifungals

    • What is the recommended curative therapy of choice for young patients with Fanconi's anaemia?

  • Bone marrow transplantation (correct)
  • Antibiotic therapy
  • Anabolic steroids
  • Platelet transfusions

    • Which adverse drug reaction category does aplastic anaemia caused by chloramphenicol fall under?

    <p>Type B adverse reaction</p> Signup and view all the answers

    In cases where bone marrow transplantation is not an option, what medications are suggested to reduce transfusion requirements in Fanconi's anaemia patients?

    <p>Anabolic steroids and G-CSF</p> Signup and view all the answers

    Which factor is used in patients with factor IX deficiency?

    <p>Factor IX</p> Signup and view all the answers

    What does serum ferritin concentration correlate with?

    <p>Body iron stores</p> Signup and view all the answers

    What is the main function of recombinant activated factor VII (rFVIIa)?

    <p>Achievement of hemostasis</p> Signup and view all the answers

    What are the common adverse effects of factor IX infusions?

    <p>Anaphylactic reactions</p> Signup and view all the answers

    What characterizes aplastic anemia?

    <p>Pancytopenia with absence of hematological precursors in the marrow</p> Signup and view all the answers

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