Drugs for Anemia and Hematological Disorders

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What is the most commonly implicated aetiological agent in acquired Fanconi's anaemia?

Drug

Which type of drugs can predictably cause aplastic anaemia if given in sufficient doses?

Alkylating agents

What is the recommended curative therapy of choice for young patients with Fanconi's anaemia?

Bone marrow transplantation

Which adverse drug reaction category does aplastic anaemia caused by chloramphenicol fall under?

<p>Type B adverse reaction</p> Signup and view all the answers

In cases where bone marrow transplantation is not an option, what medications are suggested to reduce transfusion requirements in Fanconi's anaemia patients?

<p>Anabolic steroids and G-CSF</p> Signup and view all the answers

Which factor is used in patients with factor IX deficiency?

<p>Factor IX</p> Signup and view all the answers

What does serum ferritin concentration correlate with?

<p>Body iron stores</p> Signup and view all the answers

What is the main function of recombinant activated factor VII (rFVIIa)?

<p>Achievement of hemostasis</p> Signup and view all the answers

What are the common adverse effects of factor IX infusions?

<p>Anaphylactic reactions</p> Signup and view all the answers

What characterizes aplastic anemia?

<p>Pancytopenia with absence of hematological precursors in the marrow</p> Signup and view all the answers

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