Drugs and Therapies in Retinal Diseases Management

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What is the primary mechanism of photodynamic therapy in treating wet age-related macular degeneration?

Suppressing retinal angiogenesis

Inducing cell death through the generation of reactive oxygen species (correct)

Restoring tissue oxygenation

Inhibiting vascular endothelial growth factor

What is the advantage of photodynamic therapy in managing retinal vascular diseases?

It promotes wound healing and rejuvenation

It reduces the formation of scar tissue and disfigurement (correct)

It requires lengthy recuperation

It is a highly invasive treatment strategy

What is the role of the light source in photodynamic therapy?

To activate the photosensitizer (correct)

To inhibit vascular endothelial growth factor

To generate reactive oxygen species

To promote tissue oxygenation

What is the effect of photodynamic therapy on retinal angiogenesis?

It suppresses retinal angiogenesis Signup and view all the answers

What is the primary target of VEGF inhibitors in managing retinal vascular diseases?

Vascular endothelial growth factor Signup and view all the answers

What is the relationship between photodynamic therapy and verteporfin therapy?

Verteporfin therapy is a type of photodynamic therapy Signup and view all the answers

What is the minimum visual acuity required for verteporfin therapy in ARMD?

20/200 Signup and view all the answers

What is the wavelength of non-thermal laser light used in verteporfin therapy?

689 nm Signup and view all the answers

What is the recommended interval for retreatments in verteporfin therapy if there is still angiographic evidence of leakage from the CNVM?

Three monthly intervals Signup and view all the answers

What is the original name of Vascular Endothelial Growth Factor (VEGF)?

Vascular Permeability Factor (VPF) Signup and view all the answers

What is the duration of avoidance of sun exposure and bright interior light exposure after verteporfin therapy in the US standard?

5 days Signup and view all the answers

What is a contraindication for the use of verteporfin therapy?

Breast-feeding Signup and view all the answers

What is the primary mechanism of action of the VEGF Trap in reducing excess foveal thickness?

By blocking the activity of endogenous VEGF in angiogenesis Signup and view all the answers

What is a significant adverse effect of the Retisert implant in the management of chronic non-infectious posterior uveitis?

Cataract progression Signup and view all the answers

What is the primary use of Anecortave in the treatment of retinal diseases?

Treatment of age-related macular degeneration Signup and view all the answers

What is the mechanism of action of Squalamine in reducing angiogenesis?

By possessing anti-angiogenic activity Signup and view all the answers

What is the purpose of using VEGF inhibitors in the management of retinal vascular diseases?

To reduce excess foveal thickness Signup and view all the answers

What is the chemical structure of Anecortave similar to?

Corticosteroid hydrocortisone Signup and view all the answers