Drugs and Therapies in Retinal Diseases Management
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Questions and Answers

What is the primary mechanism of photodynamic therapy in treating wet age-related macular degeneration?

  • Suppressing retinal angiogenesis
  • Inducing cell death through the generation of reactive oxygen species (correct)
  • Restoring tissue oxygenation
  • Inhibiting vascular endothelial growth factor

What is the advantage of photodynamic therapy in managing retinal vascular diseases?

  • It promotes wound healing and rejuvenation
  • It reduces the formation of scar tissue and disfigurement (correct)
  • It requires lengthy recuperation
  • It is a highly invasive treatment strategy

What is the role of the light source in photodynamic therapy?

  • To activate the photosensitizer (correct)
  • To inhibit vascular endothelial growth factor
  • To generate reactive oxygen species
  • To promote tissue oxygenation

What is the effect of photodynamic therapy on retinal angiogenesis?

<p>It suppresses retinal angiogenesis (B)</p> Signup and view all the answers

What is the primary target of VEGF inhibitors in managing retinal vascular diseases?

<p>Vascular endothelial growth factor (B)</p> Signup and view all the answers

What is the relationship between photodynamic therapy and verteporfin therapy?

<p>Verteporfin therapy is a type of photodynamic therapy (C)</p> Signup and view all the answers

What is the minimum visual acuity required for verteporfin therapy in ARMD?

<p>20/200 (A)</p> Signup and view all the answers

What is the wavelength of non-thermal laser light used in verteporfin therapy?

<p>689 nm (D)</p> Signup and view all the answers

What is the recommended interval for retreatments in verteporfin therapy if there is still angiographic evidence of leakage from the CNVM?

<p>Three monthly intervals (D)</p> Signup and view all the answers

What is the original name of Vascular Endothelial Growth Factor (VEGF)?

<p>Vascular Permeability Factor (VPF) (A)</p> Signup and view all the answers

What is the duration of avoidance of sun exposure and bright interior light exposure after verteporfin therapy in the US standard?

<p>5 days (D)</p> Signup and view all the answers

What is a contraindication for the use of verteporfin therapy?

<p>Breast-feeding (A)</p> Signup and view all the answers

What is the primary mechanism of action of the VEGF Trap in reducing excess foveal thickness?

<p>By blocking the activity of endogenous VEGF in angiogenesis (D)</p> Signup and view all the answers

What is a significant adverse effect of the Retisert implant in the management of chronic non-infectious posterior uveitis?

<p>Cataract progression (D)</p> Signup and view all the answers

What is the primary use of Anecortave in the treatment of retinal diseases?

<p>Treatment of age-related macular degeneration (A)</p> Signup and view all the answers

What is the mechanism of action of Squalamine in reducing angiogenesis?

<p>By possessing anti-angiogenic activity (D)</p> Signup and view all the answers

What is the purpose of using VEGF inhibitors in the management of retinal vascular diseases?

<p>To reduce excess foveal thickness (D)</p> Signup and view all the answers

What is the chemical structure of Anecortave similar to?

<p>Corticosteroid hydrocortisone (D)</p> Signup and view all the answers

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