Drugs Affecting Cardiovascular System

A substance increasing urine production by excreting water and electrolytes (like sodium and chloride).

Increased production of urine.

A molecular interaction where the presence of bulky substituents prevents certain reactions or interactions. Bulkiness prevents access.

Not in the same plane; molecules with different orientations.

An atom or group that pulls electron density away from other parts of a molecule, affecting reactivity.

Replacing a part of a benzene ring with another group.

Electron-donating group, increases anticancer activity when substituted onto a benzene ring.

Electron-withdrawing group, decreases anticancer activity when substituted onto a benzene ring.

A ring structure with specific bonding patterns called "aromaticity".

A ring structure that is not aromatic.

The ability of a substance to kill or inhibit the growth of cancer cells.

Electron-donating groups on aromatic rings generally have more anticancer activity and their activity decreases through aliphatic to aromatic and further more, to electron-withdrawing groups on aromatic rings..

A molecule that decreases platelet aggregation and promotes vasodilation.

The clumping of platelets, promoting blood clotting.

Widening of blood vessels.

A medication that prevents platelet aggregation by altering cAMP levels to reduce clot formation.

A condition where the number of neutrophils (a type of white blood cell) is abnormally low.

An older antiplatelet drug replaced by clopidogrel due to a potential adverse effect.

Groups that release electrons, increasing electron density.

Unbonded electrons on the nitrogen atom.

Formation of a positively charged ring structure containing nitrogen.

The ability to inhibit or kill cancer cells.

Electron donating groups facilitate Aziridinium cation formation.

A medical application of something to fight cancer.

Diseases where the body's immune system attacks its own tissues.

An autoimmune disease causing inflammation in the joints.

Medicines used to treat viral infections.

A pathogen that needs to enter a host cell to replicate.

A cell that is infected or invaded by a pathogen.

The process of viruses making copies of themselves.

Protein channels that allow protons (H+) to enter a virus, acidifying it.

The process of making the inside of a virus more acidic by allowing protons to enter.

The process of a virus releasing its genetic material (RNA) due to acidification.

The process of a virus making copies of itself inside a cell.

Drugs that block the action of M2 channels, preventing virus acidification.