Antitubercular Drugs and Tuberculosis

Antitubercular Drugs

• Classified into first-line and second-line drugs
• First-line drugs are used to treat first infection episode, reinfection, and dormant TB
• Multidrug-Resistant Tuberculosis (MDR-TB) is a significant concern

Tuberculosis (TB) Concepts

• PPD (Purified Protein Derivative) is a diagnostic tool for TB
• Incidence of TB refers to the number of new cases per year
• Dormancy refers to the latent state of TB

Antitubercular Drug Therapy

• Bedaquiline (Sirturo) is an oral medication used to treat MDR-TB
• Isoniazid is a first-line drug used to treat TB, with considerations for therapy
• Rifabutin, Rifampin, and Rifapentine are antibiotics used to treat TB, with specific considerations
• Adverse effects of antitubercular drugs must be monitored
• Nursing implications for antitubercular drug therapy are crucial

NSAIDs (Nonsteroidal Anti-Inflammatory Drugs)

• Used to treat inflammatory conditions, such as arthritis
• Classified into acetic acid derivatives and cyclooxygenase-2 (COX-2) inhibitors
• Acetic acid derivatives include:
  • Diclofenac sodium (Voltaren)
  • Indomethacin (Indocin)
  • Sulindac (Clinoril)
  • Tolmetin (Tolectin)
  • Etodolac (Lodine)
  • Ketorolac (Toradol)

This quiz covers antitubercular drugs, their classification, and treatment of tuberculosis including first-line and second-line drugs. It also covers concepts such as multidrug-resistant tuberculosis and PPD.