Antitubercular Drugs and Tuberculosis
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Questions and Answers

What is the term used to describe a patient who has had tuberculosis in the past and has a new infection?

  • First Infections Episode
  • Incidence
  • Dormancy
  • Reinfection (correct)

Which of the following antitubercular drugs is a COX-2 inhibitor?

  • Rifampin
  • Isoniazid
  • Rifabutin
  • None of the above (correct)

What is the primary use of Bedaquiline (Sirturo)?

  • Treatment of multidrug-resistant tuberculosis (MDR-TB) (correct)
  • Treatment of first infection episodes
  • Treatment of dormancy
  • Treatment of reinfection

What is the primary mechanism of action of Isoniazid?

<p>Inhibiting the synthesis of mycolic acid (D)</p> Signup and view all the answers

What is the term used to describe the skin test used to diagnose tuberculosis?

<p>PPD (A)</p> Signup and view all the answers

Study Notes

Antitubercular Drugs

  • Classified into first-line and second-line drugs
  • First-line drugs are used to treat first infection episode, reinfection, and dormant TB
  • Multidrug-Resistant Tuberculosis (MDR-TB) is a significant concern

Tuberculosis (TB) Concepts

  • PPD (Purified Protein Derivative) is a diagnostic tool for TB
  • Incidence of TB refers to the number of new cases per year
  • Dormancy refers to the latent state of TB

Antitubercular Drug Therapy

  • Bedaquiline (Sirturo) is an oral medication used to treat MDR-TB
  • Isoniazid is a first-line drug used to treat TB, with considerations for therapy
  • Rifabutin, Rifampin, and Rifapentine are antibiotics used to treat TB, with specific considerations
  • Adverse effects of antitubercular drugs must be monitored
  • Nursing implications for antitubercular drug therapy are crucial

NSAIDs (Nonsteroidal Anti-Inflammatory Drugs)

  • Used to treat inflammatory conditions, such as arthritis
  • Classified into acetic acid derivatives and cyclooxygenase-2 (COX-2) inhibitors
  • Acetic acid derivatives include:
    • Diclofenac sodium (Voltaren)
    • Indomethacin (Indocin)
    • Sulindac (Clinoril)
    • Tolmetin (Tolectin)
    • Etodolac (Lodine)
    • Ketorolac (Toradol)

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Description

This quiz covers antitubercular drugs, their classification, and treatment of tuberculosis including first-line and second-line drugs. It also covers concepts such as multidrug-resistant tuberculosis and PPD.

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