Broth Dilution Method for Susceptibility Testing
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Questions and Answers

Which method represents the gold standard for susceptibility testing?

  • Automated method
  • Disk diffusion method
  • Minimum bactericidal concentration method
  • Broth dilution method (correct)
  • What does MIC stand for in susceptibility testing?

  • Minimum Inhibition Concentration
  • Minimum Inhibitory Concentration (correct)
  • Maximum Inhibition Concentration
  • Minimum Infectious Concentration
  • Which method involves placing fibrous disks or strips containing drug concentrations on agar plates?

  • Automated method
  • Broth dilution method
  • Minimum bactericidal concentration method
  • Disk diffusion method (correct)
  • What represents a continuum rather than a dichotomy in susceptibility testing?

    <p>Sensitivity and Resistance</p> Signup and view all the answers

    In the automated method, what does the machine do with the standardized inoculum of the organism?

    <p>Performs a technique similar to broth dilution method</p> Signup and view all the answers

    Which body fluid can be used to correlate the MIC with achievable concentrations at the site of infection?

    <p>Cerebrospinal fluid (CSF)</p> Signup and view all the answers

    What is the MIC range that defines a pneumoniae strain as resistant to penicillin?

    <p>Greater than 1 mcg/mL</p> Signup and view all the answers

    Which reference source is mentioned for compiling and updating antimicrobial therapy data?

    <p>CDC Website</p> Signup and view all the answers

    Why should sulfonamides and penicillinase-resistant penicillins be avoided in late pregnancy and neonates?

    <p>They may cause kernicterus</p> Signup and view all the answers

    In what situations are bactericidal drugs, like penicillins, preferred in patients?

    <p>Immunocompromised patients</p> Signup and view all the answers

    Which factor is highlighted as a consideration in drug selection due to patient acceptance?

    <p>Adherence based on taste</p> Signup and view all the answers

    What is the main reason behind choosing amoxicillin as the drug of choice for common infections?

    <p>$4 generic cost</p> Signup and view all the answers

    Why might amoxicillin be preferred over penicillin V for group A streptococcal infections?

    <p>$4 generic cost</p> Signup and view all the answers

    What is a significant factor affecting patient compliance with a prescribed antibiotic regimen?

    <p><em>Taste</em> of the medication</p> Signup and view all the answers

    In what scenario might penicillins require higher doses, IV administration, or prolonged therapy?

    <p><em>CNS</em> infections</p> Signup and view all the answers

    Which outcome is important to monitor specifically in pneumonia cases during treatment?

    <p>Resolution of pulmonary infiltrates</p> Signup and view all the answers

    What should patients be advised to do if there is no improvement in their condition after 48 to 72 hours of antibiotic treatment?

    <p>Call the prescriber for evaluation</p> Signup and view all the answers

    What are common signs of improvement that should be monitored in patients during antibiotic therapy?

    <p>Normalization of pulse oximetry</p> Signup and view all the answers

    In case of more than three watery, unformed stools per day or blood in the stool during antibiotic therapy, what should be done?

    <p>Consider stool testing for C. difficile toxin</p> Signup and view all the answers

    What is a potential consequence of not completing a full course of antibiotic therapy?

    <p>Development of resistant infections</p> Signup and view all the answers

    Why should doses of antibiotics be spaced evenly throughout the day?

    <p>To ensure maximum absorption and effectiveness</p> Signup and view all the answers

    What is the correct action if a patient misses a dose of penicillin V?

    <p>Skip that dose and continue with the next scheduled dose</p> Signup and view all the answers

    Why should patients avoid crushing chewable tablets of penicillin V or dicloxacillin?

    <p>To improve drug absorption</p> Signup and view all the answers

    What is important about the clavulanate content in oral tablets and chewable tablets of amoxicillin/clavulanate?

    <p>'The clavulanate content is higher in chewable tablets.'</p> Signup and view all the answers

    Why should liquid formulations of antibiotics always be dispensed with a calibrated measuring device?

    <p>Because household teaspoons vary widely in volume and are unreliable for accurate measurement.</p> Signup and view all the answers

    What is the importance of telling patients whether there will be liquid medication remaining at the end of their therapy course?

    <p>To encourage patients to finish all the medication.</p> Signup and view all the answers

    What should be done if severe diarrhea occurs in a patient taking penicillins?

    <p>Contact the prescriber before initiating any treatment.</p> Signup and view all the answers

    Why are lifestyle management and prevention strategies important in reducing antibiotic usage?

    <p>To promote healthier practices that limit the occurrence of infections.</p> Signup and view all the answers

    What should diabetic patients taking aminopenicillins and clavulanate do to obtain accurate glucose testing results?

    <p>Rely on urine testing based on glucose enzymatic tests.</p> Signup and view all the answers

    How can healthcare providers minimize pain and prevent needle blockage during intramuscular injection of thick preparations like procaine and benzathine?

    <p>Injecting slowly over 12 to 15 seconds.</p> Signup and view all the answers

    Why is it important for patients to be able to distinguish allergic reactions from other adverse effects of medications?

    <p>To provide an accurate drug allergy history.</p> Signup and view all the answers

    Why should patients with immediate allergic reactions wear an identification bracelet?

    <p>To alert healthcare providers of their allergy in case of emergencies.</p> Signup and view all the answers

    What can patients use to manage mild diarrhea caused by penicillins?

    <p>Adsorbent antidiarrheal agents like Donnagel containing attapulgite.</p> Signup and view all the answers

    Why is it advised to consult the package insert for proper mixing and storage of reconstituted parenteral penicillins?

    <p>To know the volume limits for IM injection sites.</p> Signup and view all the answers

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