Broth Dilution Method for Susceptibility Testing
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Questions and Answers

Which method represents the gold standard for susceptibility testing?

  • Automated method
  • Disk diffusion method
  • Minimum bactericidal concentration method
  • Broth dilution method (correct)

What does MIC stand for in susceptibility testing?

  • Minimum Inhibition Concentration
  • Minimum Inhibitory Concentration (correct)
  • Maximum Inhibition Concentration
  • Minimum Infectious Concentration

Which method involves placing fibrous disks or strips containing drug concentrations on agar plates?

  • Automated method
  • Broth dilution method
  • Minimum bactericidal concentration method
  • Disk diffusion method (correct)

What represents a continuum rather than a dichotomy in susceptibility testing?

<p>Sensitivity and Resistance (C)</p> Signup and view all the answers

In the automated method, what does the machine do with the standardized inoculum of the organism?

<p>Performs a technique similar to broth dilution method (A)</p> Signup and view all the answers

Which body fluid can be used to correlate the MIC with achievable concentrations at the site of infection?

<p>Cerebrospinal fluid (CSF) (D)</p> Signup and view all the answers

What is the MIC range that defines a pneumoniae strain as resistant to penicillin?

<p>Greater than 1 mcg/mL (B)</p> Signup and view all the answers

Which reference source is mentioned for compiling and updating antimicrobial therapy data?

<p>CDC Website (C)</p> Signup and view all the answers

Why should sulfonamides and penicillinase-resistant penicillins be avoided in late pregnancy and neonates?

<p>They may cause kernicterus (C)</p> Signup and view all the answers

In what situations are bactericidal drugs, like penicillins, preferred in patients?

<p>Immunocompromised patients (A)</p> Signup and view all the answers

Which factor is highlighted as a consideration in drug selection due to patient acceptance?

<p>Adherence based on taste (D)</p> Signup and view all the answers

What is the main reason behind choosing amoxicillin as the drug of choice for common infections?

<p>$4 generic cost (B)</p> Signup and view all the answers

Why might amoxicillin be preferred over penicillin V for group A streptococcal infections?

<p>$4 generic cost (C)</p> Signup and view all the answers

What is a significant factor affecting patient compliance with a prescribed antibiotic regimen?

<p><em>Taste</em> of the medication (A)</p> Signup and view all the answers

In what scenario might penicillins require higher doses, IV administration, or prolonged therapy?

<p><em>CNS</em> infections (B)</p> Signup and view all the answers

Which outcome is important to monitor specifically in pneumonia cases during treatment?

<p>Resolution of pulmonary infiltrates (D)</p> Signup and view all the answers

What should patients be advised to do if there is no improvement in their condition after 48 to 72 hours of antibiotic treatment?

<p>Call the prescriber for evaluation (A)</p> Signup and view all the answers

What are common signs of improvement that should be monitored in patients during antibiotic therapy?

<p>Normalization of pulse oximetry (D)</p> Signup and view all the answers

In case of more than three watery, unformed stools per day or blood in the stool during antibiotic therapy, what should be done?

<p>Consider stool testing for C. difficile toxin (A)</p> Signup and view all the answers

What is a potential consequence of not completing a full course of antibiotic therapy?

<p>Development of resistant infections (A)</p> Signup and view all the answers

Why should doses of antibiotics be spaced evenly throughout the day?

<p>To ensure maximum absorption and effectiveness (A)</p> Signup and view all the answers

What is the correct action if a patient misses a dose of penicillin V?

<p>Skip that dose and continue with the next scheduled dose (A)</p> Signup and view all the answers

Why should patients avoid crushing chewable tablets of penicillin V or dicloxacillin?

<p>To improve drug absorption (C)</p> Signup and view all the answers

What is important about the clavulanate content in oral tablets and chewable tablets of amoxicillin/clavulanate?

<p>'The clavulanate content is higher in chewable tablets.' (F)</p> Signup and view all the answers

Why should liquid formulations of antibiotics always be dispensed with a calibrated measuring device?

<p>Because household teaspoons vary widely in volume and are unreliable for accurate measurement. (C)</p> Signup and view all the answers

What is the importance of telling patients whether there will be liquid medication remaining at the end of their therapy course?

<p>To encourage patients to finish all the medication. (A)</p> Signup and view all the answers

What should be done if severe diarrhea occurs in a patient taking penicillins?

<p>Contact the prescriber before initiating any treatment. (A)</p> Signup and view all the answers

Why are lifestyle management and prevention strategies important in reducing antibiotic usage?

<p>To promote healthier practices that limit the occurrence of infections. (B)</p> Signup and view all the answers

What should diabetic patients taking aminopenicillins and clavulanate do to obtain accurate glucose testing results?

<p>Rely on urine testing based on glucose enzymatic tests. (A)</p> Signup and view all the answers

How can healthcare providers minimize pain and prevent needle blockage during intramuscular injection of thick preparations like procaine and benzathine?

<p>Injecting slowly over 12 to 15 seconds. (D)</p> Signup and view all the answers

Why is it important for patients to be able to distinguish allergic reactions from other adverse effects of medications?

<p>To provide an accurate drug allergy history. (D)</p> Signup and view all the answers

Why should patients with immediate allergic reactions wear an identification bracelet?

<p>To alert healthcare providers of their allergy in case of emergencies. (D)</p> Signup and view all the answers

What can patients use to manage mild diarrhea caused by penicillins?

<p>Adsorbent antidiarrheal agents like Donnagel containing attapulgite. (C)</p> Signup and view all the answers

Why is it advised to consult the package insert for proper mixing and storage of reconstituted parenteral penicillins?

<p>To know the volume limits for IM injection sites. (C)</p> Signup and view all the answers

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