Podcast
Questions and Answers
What is the main problem associated with the quench cooling technique?
What is the main problem associated with the quench cooling technique?
- Inability to convert drugs into amorphous form
- Low yield due to formation on a small scale (correct)
- High material loss due to sticking to surfaces
- Time-consuming process
Which technique is known for being very high yield, continuous, and having low labor costs?
Which technique is known for being very high yield, continuous, and having low labor costs?
- Supercritical fluid impregnation
- Quench cooling
- Hot melt extrusion (correct)
- Ball milling
What is a drawback of ball milling as mentioned in the text?
What is a drawback of ball milling as mentioned in the text?
- Time-consuming with less material conversion (correct)
- Inability to convert drugs into amorphous form
- Loss of material due to sticking to surfaces
- Not suitable for heat-sensitive drugs
Which technique involves the use of a supercritical fluid like CO2?
Which technique involves the use of a supercritical fluid like CO2?
What is a benefit of the supercritical fluid impregnation technique for drug dispersion?
What is a benefit of the supercritical fluid impregnation technique for drug dispersion?
Why is hot melt extrusion not suitable for heat-sensitive substances?
Why is hot melt extrusion not suitable for heat-sensitive substances?
What is the main characteristic of BCS 2 drugs described in the text?
What is the main characteristic of BCS 2 drugs described in the text?
How does reducing particle size enhance drug solubility according to the text?
How does reducing particle size enhance drug solubility according to the text?
What method can be used to ensure the drug is ionized for stronger ionic bonds with the dissolution medium?
What method can be used to ensure the drug is ionized for stronger ionic bonds with the dissolution medium?
Why do amorphous solids have higher solubility compared to crystalline solids?
Why do amorphous solids have higher solubility compared to crystalline solids?
What distinguishes amorphous solids from crystalline solids in terms of molecule arrangement?
What distinguishes amorphous solids from crystalline solids in terms of molecule arrangement?
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