Recent Lessons

Show all results for ""

Feature Overview

Ace your exams with our all-in-one platform for creating and sharing quizzes and tests.

Quizzes

Create quizzes and tests automatically from your content using AI.

Flashcards

Automatically turn your notes into digital flashcards.

Share, Export & Embed

Share with classmates or export to Excel and your learning management system.

Stats & Reporting

Auto-grading quizzes and tests with detailed stats and reports.

Mobile Apps

The smarter way to study – wherever you are.

Pricing

Search...

Drug Receptor Interactions and Antagonists Quiz

14 Questions

1 Views

Drug Receptor Interactions and Antagonists Quiz

Choose a study mode

Play Quiz

Study Flashcards

Spaced Repetition

Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is the correct definition of an 'antagonist'?

A ligand that has an intrinsic activity of 1.

A ligand that binds to a receptor and causes a biological response.

A ligand that prevents the effects of an agonist. (correct)

A ligand that binds to a receptor and has no effect.

What is the effect of a reversible competitive antagonist on a log dose response curve?

It causes a decrease in the maximum response.

It has no effect on the curve.

It shifts the curve to the left.

It shifts the curve to the right. (correct)

What is the effect of a non-competitive antagonist on a log dose response curve?

It causes a decrease in the maximum response.

It shifts the curve to the right.

It shifts the curve to the left.

It has no effect on the curve. (correct)

Which type of antagonist binds to the same site as the endogenous ligand?

Competitive Signup and view all the answers

What is the main difference between reversible and irreversible antagonists?

Reversible antagonists can be easily reversed by increasing the concentration of the agonist while irreversible antagonists cannot Signup and view all the answers

What is the median effective dose (ED50)?

The dose required to produce a specified response in 50% of the population Signup and view all the answers

What is the difference between therapeutic index and therapeutic window?

Therapeutic index refers to the range of doses that produce a therapeutic effect, while therapeutic window refers to the range of doses that produce a toxic effect Signup and view all the answers

Which of the following receptor types is regulated by a desensitized state with higher affinity for the agon?

Ligand-gated ion channels Signup and view all the answers

Which type of receptor is characterized by containing receptor subunits around a 'central pore' that also acts as the ion channel?

Ligand-gated ion channels Signup and view all the answers

Which receptor type 'receives' and 'transmits' signals through receptor tyrosine kinases?

Receptor tyrosine kinases Signup and view all the answers

Which of the following is true about receptor tyrosine kinases (RTKs)?

RTKs have an extracellular domain responsible for capturing signal Signup and view all the answers

Which of the following is true about Growth receptor binding protein 2 (Grb2)?

Grb2 is an adapter protein that links signaling molecules Signup and view all the answers

Which of the following is true about Ras?

Ras binds GTP to become active Signup and view all the answers

Which of the following is true about nuclear receptors?

Nuclear receptors require phosphorylation for activation Signup and view all the answers