Drug Pharmacokinetics Quiz
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Questions and Answers

What does the elimination half-life depend on?

  • The time of day the drug is taken
  • The duration of drug therapy
  • Initial concentration of the drug
  • Clearance and volume of distribution of the drug (correct)

    • What is the half-life of a drug?

  • The time required for the body to eliminate one half of the drug it contains (correct)
  • The time required for the body to eliminate one quarter of the drug it contains
  • The time required for the body to eliminate all of the drug it contains
  • The time required for the body to eliminate three quarters of the drug it contains

    • What is the characteristic of exponential decay in relation to half-life?

  • The time required for a given fraction of drug to disappear decreases over time
  • The time required for a given fraction of drug to disappear is always the same (correct)
  • The time required for a given fraction of drug to disappear increases over time
  • The time required for a given fraction of drug to disappear varies with initial concentration

    • What is the biological half-life not indicative of?

    <p>The time for the response to decline by 50%</p> Signup and view all the answers

    What is the formula for elimination half-life (t ½)?

    <p>$t_{1/2} = 0.693/K_{elim}$</p> Signup and view all the answers

    What is the characteristic of exponential decay in relation to half-life?

    <p>The time required for a given fraction of drug to disappear is always the same, regardless of the time or concentration at which one begins measurements.</p> Signup and view all the answers

    What does the biological half-life indicate?

    <p>The time needed to decrease the body drug level by one half of its initial level.</p> Signup and view all the answers

    What factors cause non-parallelism between blood concentration and pharmacological response intensity?

    <p>Threshold concentration and latency of response.</p> Signup and view all the answers

    What is the formula for elimination half-life ($t_{1/2}$)?

    <p>$t_{1/2} = 0.693 / Kelim$</p> Signup and view all the answers

    What does the half-life of a drug determine?

    <p>The time required for the body to eliminate by metabolizing, or excretion, or by both, one half of the initial dose of the drug.</p> Signup and view all the answers

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