Questions and Answers
Which mechanism of drug absorption typically involves transfer across most biological membranes?
Passive diffusion
Which process involves drug transfer from the site of administration to the bloodstream?
Absorption
What type of diffusion involves carrier proteins but does not require energy?
Facilitated diffusion
Which of the following routes of drug administration is NOT mentioned in the text?
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Which type of reactions involve amine oxidation and alcohol dehydrogenation in drug metabolism?
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Inhibition of CYP450 can lead to serious adverse events. Which of the following is NOT an inhibitor of CYP450 according to the text?
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Which of the following is NOT a substance that can lead to increased toxic effects when combined with drugs like nifedipine and simvastatin?
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Which of the following groups allows drugs to enter phase II directly without prior phase I metabolism?
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Which set of reactions involves introducing or unmasking a polar functional group in drug metabolism?
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Where are the cytochrome P450 isozymes primarily located?
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Which type of drugs or environmental pollutants may induce the activity of CYP450 isozymes?
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Which drug is mentioned as an example that can decrease concentrations of drugs metabolized by CYP450 isozymes?
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