Drug Metabolism: First-Pass, Inducers, Inhibitors

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Questions and Answers

Which drug from the list is known to undergo first-pass metabolism?

  • Griseofulvin
  • Ciprofloxacin
  • Verapamil
  • Nitroglycerin (correct)

Which among the listed substances is considered an enzyme inducer?

  • Meprobamate (correct)
  • Valproic acid
  • Meperidine
  • Salicylamide

Which enzyme inhibitor is commonly found in grapefruit juice?

  • Omeprazole (correct)
  • Phenobarbital
  • Isoniazid
  • Disulfiram

Which enzyme inducer is associated with chronic alcoholism?

<p>Rifampicin (D)</p> Signup and view all the answers

Which drug is an example of a compound that can be affected by both enzyme inducers and enzyme inhibitors?

<p>Indinavir (B)</p> Signup and view all the answers

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Study Notes

Enzyme Inducers and Inhibitors

  • First-pass metabolism occurs with one specific drug from the list.
  • An enzyme inducer is a type of substance that can increase the production of enzymes.
  • Grapefruit juice is a common source of enzyme inhibitors.
  • Chronic alcoholism is associated with a specific enzyme inducer.
  • Certain drugs can be affected by both enzyme inducers and enzyme inhibitors, one example is a specific compound from the list.

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