Drug Metabolism: First-Pass, Inducers, Inhibitors

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Questions and Answers

Which drug from the list is known to undergo first-pass metabolism?

Nitroglycerin

Which among the listed substances is considered an enzyme inducer?

Meprobamate

Which enzyme inhibitor is commonly found in grapefruit juice?

Omeprazole

Which enzyme inducer is associated with chronic alcoholism?

<p>Rifampicin</p> Signup and view all the answers

Which drug is an example of a compound that can be affected by both enzyme inducers and enzyme inhibitors?

<p>Indinavir</p> Signup and view all the answers

Study Notes

Enzyme Inducers and Inhibitors

  • First-pass metabolism occurs with one specific drug from the list.
  • An enzyme inducer is a type of substance that can increase the production of enzymes.
  • Grapefruit juice is a common source of enzyme inhibitors.
  • Chronic alcoholism is associated with a specific enzyme inducer.
  • Certain drugs can be affected by both enzyme inducers and enzyme inhibitors, one example is a specific compound from the list.

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