Drug Metabolism: First-Pass, Inducers, Inhibitors
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Questions and Answers

Which drug from the list is known to undergo first-pass metabolism?

  • Griseofulvin
  • Ciprofloxacin
  • Verapamil
  • Nitroglycerin (correct)
  • Which among the listed substances is considered an enzyme inducer?

  • Meprobamate (correct)
  • Valproic acid
  • Meperidine
  • Salicylamide
  • Which enzyme inhibitor is commonly found in grapefruit juice?

  • Omeprazole (correct)
  • Phenobarbital
  • Isoniazid
  • Disulfiram
  • Which enzyme inducer is associated with chronic alcoholism?

    <p>Rifampicin</p> Signup and view all the answers

    Which drug is an example of a compound that can be affected by both enzyme inducers and enzyme inhibitors?

    <p>Indinavir</p> Signup and view all the answers

    Study Notes

    Enzyme Inducers and Inhibitors

    • First-pass metabolism occurs with one specific drug from the list.
    • An enzyme inducer is a type of substance that can increase the production of enzymes.
    • Grapefruit juice is a common source of enzyme inhibitors.
    • Chronic alcoholism is associated with a specific enzyme inducer.
    • Certain drugs can be affected by both enzyme inducers and enzyme inhibitors, one example is a specific compound from the list.

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    Description

    Test your knowledge on drugs subject to first-pass metabolism, enzyme inducers, and enzyme inhibitors with this quiz. Identify drugs like Morphine, Phenytoin, and Erythromycin and understand their metabolic pathways.

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