Podcast
Questions and Answers
Which of the following is NOT a key process in the pharmacokinetics of a drug?
Which of the following is NOT a key process in the pharmacokinetics of a drug?
- Absorption
- Distribution
- Excretion (correct)
- Metabolism
What is the term used to describe the maximum concentration of a drug in the plasma?
What is the term used to describe the maximum concentration of a drug in the plasma?
- Tmax
- Elimination phase
- Therapeutic window
- C Max (correct)
What is the desired level of drug concentration for therapeutic dosing?
What is the desired level of drug concentration for therapeutic dosing?
- Minimal effective concentration (correct)
- Elimination phase
- Therapeutic window
- Tmax
Which of the following is a main route of drug excretion?
Which of the following is a main route of drug excretion?
What determines the affinity of drugs for transporters in the nephron?
What determines the affinity of drugs for transporters in the nephron?
What is drug clearance?
What is drug clearance?
Which factor determines the magnitude of VD for drugs?
Which factor determines the magnitude of VD for drugs?
What does the term 'half-life' refer to?
What does the term 'half-life' refer to?
What does the slope of K denote in the concentration decay?
What does the slope of K denote in the concentration decay?
Which route of drug administration has an instant rate of absorption?
Which route of drug administration has an instant rate of absorption?
Which type of drug administration shows a linear rate of absorption with time?
Which type of drug administration shows a linear rate of absorption with time?
Which process involves enzymatic conversion of a drug to a metabolite?
Which process involves enzymatic conversion of a drug to a metabolite?
Which of the following is a factor that influences drug clearance?
Which of the following is a factor that influences drug clearance?
What is the volume of distribution (VD) in pharmacokinetics?
What is the volume of distribution (VD) in pharmacokinetics?
Which form of the drug can cross over the porous capillary membranes?
Which form of the drug can cross over the porous capillary membranes?
Which of the following is NOT a key process in the pharmacokinetics of a drug?
Which of the following is NOT a key process in the pharmacokinetics of a drug?
What is the term used to describe the maximum concentration of a drug in the plasma?
What is the term used to describe the maximum concentration of a drug in the plasma?
What does the term 'half-life' refer to?
What does the term 'half-life' refer to?
Which organ clearances are included in the calculation of drug clearance?
Which organ clearances are included in the calculation of drug clearance?
What is the formula for calculating drug clearance after intravenous dosing?
What is the formula for calculating drug clearance after intravenous dosing?
What is the definition of bioavailability?
What is the definition of bioavailability?
Which of the following is true about drug absorption via infusion?
Which of the following is true about drug absorption via infusion?
Which process makes a drug more water-soluble by oxidation, reduction, or hydrolysis?
Which process makes a drug more water-soluble by oxidation, reduction, or hydrolysis?
Which enzyme family is responsible for metabolizing a majority of drugs?
Which enzyme family is responsible for metabolizing a majority of drugs?
Which of the following factors determines the volume of distribution (VD) of a drug?
Which of the following factors determines the volume of distribution (VD) of a drug?
What is the half-life of a drug?
What is the half-life of a drug?
What does the slope of K represent in the concentration decay of a drug?
What does the slope of K represent in the concentration decay of a drug?
Which of the following factors can affect the extent of renal excretion of a drug?
Which of the following factors can affect the extent of renal excretion of a drug?
What is the main function of organic anion transporters and organic cation transporters in the nephron?
What is the main function of organic anion transporters and organic cation transporters in the nephron?
What is drug clearance?
What is drug clearance?
Which route of drug administration is dependent on the drug being absorbed into the circulatory system?
Which route of drug administration is dependent on the drug being absorbed into the circulatory system?
What is the term used to describe the peak concentration of a drug in the plasma?
What is the term used to describe the peak concentration of a drug in the plasma?
What is the term used to describe the phase in which drug levels reduce after reaching the peak concentration?
What is the term used to describe the phase in which drug levels reduce after reaching the peak concentration?
Which route of drug administration has an absorption rate that is independent of the amount of drug present?
Which route of drug administration has an absorption rate that is independent of the amount of drug present?
Which phase of drug metabolism involves the addition of a water-soluble molecule via synthetic conjugation?
Which phase of drug metabolism involves the addition of a water-soluble molecule via synthetic conjugation?
Which enzyme family is responsible for the oxidation of drugs during phase 1 metabolism?
Which enzyme family is responsible for the oxidation of drugs during phase 1 metabolism?
Which of the following determines the magnitude of VD (volume of distribution) for drugs?
Which of the following determines the magnitude of VD (volume of distribution) for drugs?
What does the term 'half-life' refer to in pharmacokinetics?
What does the term 'half-life' refer to in pharmacokinetics?
What does the slope of K denote in the concentration decay of a drug?
What does the slope of K denote in the concentration decay of a drug?
Which of the following is true about drug excretion?
Which of the following is true about drug excretion?
What determines the affinity of drugs for transporters in the nephron?
What determines the affinity of drugs for transporters in the nephron?
What is drug clearance?
What is drug clearance?
Which of the following is NOT included in the calculation of drug clearance?
Which of the following is NOT included in the calculation of drug clearance?
What is the formula for calculating drug clearance after oral dosing?
What is the formula for calculating drug clearance after oral dosing?
What is the volume of distribution (VD) in pharmacokinetics?
What is the volume of distribution (VD) in pharmacokinetics?
What determines the magnitude of VD for drugs?
What determines the magnitude of VD for drugs?
What is the concept of half-life?
What is the concept of half-life?
What are the three types of reactions in concentration decay?
What are the three types of reactions in concentration decay?
What does the slope of K denote in concentration decay?
What does the slope of K denote in concentration decay?
What is the unit of volume for VD?
What is the unit of volume for VD?
What is the term used to describe the maximum concentration of a drug in the plasma?
What is the term used to describe the maximum concentration of a drug in the plasma?
What is the term used to describe the enzymatic conversion of a drug to a metabolite?
What is the term used to describe the enzymatic conversion of a drug to a metabolite?
What is the desired level of drug concentration for therapeutic dosing?
What is the desired level of drug concentration for therapeutic dosing?
What is the route of drug administration that depends on absorption into the circulatory system?
What is the route of drug administration that depends on absorption into the circulatory system?
What is the term used to describe the addition of a water-soluble molecule via synthetic conjugation in drug metabolism?
What is the term used to describe the addition of a water-soluble molecule via synthetic conjugation in drug metabolism?
