Drug Metabolism

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Questions and Answers

Which of the following is NOT a pathway involved in drug metabolism?

  • Alcohol oxidation (correct)
  • Aromatic hydroxylation
  • N-oxidation
  • O-dealkylation

What determines the rate of metabolism (Km) of a drug?

  • The chemical characteristics of the drug (correct)
  • The excretion rate of the drug
  • The harm of the drug
  • The benefit of the drug

What is the purpose of drug metabolism?

  • To make drugs more hydrophilic (correct)
  • To make drugs more lipophilic
  • To make drugs more toxic
  • To make drugs more stable

Which enzyme system is involved in drug metabolism?

<p>Cytochrome P450 system (A)</p> Signup and view all the answers

What is the main organ responsible for drug metabolism?

<p>Liver (B)</p> Signup and view all the answers

True or false: Drug metabolism involves 3 major pathways

<p>False (B)</p> Signup and view all the answers

True or false: Pathway I of drug metabolism is also known as the cytochrome P450 system

<p>True (A)</p> Signup and view all the answers

True or false: Drug metabolism involves the addition of hydrophilic groups to a lipophilic drug

<p>True (A)</p> Signup and view all the answers

True or false: The rate of drug metabolism depends on the benefit or harm of the drug

<p>False (B)</p> Signup and view all the answers

True or false: Aromatic hydroxylation is an example of a drug metabolism pathway

<p>True (A)</p> Signup and view all the answers

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