Drug Interactions in Anesthesia

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Questions and Answers

Which volatile anesthetic can cause prolonged apnea and enhance the effects of muscle relaxants?

  • Propofol
  • Midazolam
  • Diprivan
  • Enflurane (correct)

What type of anesthesia has replaced ethereal and cycloaliphatic halogenated agents in modern practice?

  • Local anesthesia
  • Total intravenous anesthesia (TIVA) (correct)
  • Regional anesthesia
  • Spinal anesthesia

Which IV agent can result in increased levels due to its sedative action and pose a problem with drug interactions?

  • Benzodiazepines (correct)
  • Halothane
  • Opioids
  • Suxamethonium

Which sedative and hypnotic agent can be increased by volatile anesthetics, especially in premedication and day surgery?

<p>Midazolam (D)</p> Signup and view all the answers

What severe reactions can occur if Diprivan is given to patients with egg or soy allergies?

<p>Anaphylactic reactions (D)</p> Signup and view all the answers

Co-administration of Propofol with which substance can cause severe hypotension and bradycardia?

<p>Azaperone (C)</p> Signup and view all the answers

What effect can co-administration of volatile anesthetics with adjunctive analgesics have?

<p>Reduce anesthetic dosage (B)</p> Signup and view all the answers

How do anesthetics generally interact with other central nervous system depressants?

<p>Produce additive effects (B)</p> Signup and view all the answers

Why is it crucial to understand the implications of drug interactions in anesthetic drug administration?

<p>To avoid side effects (D)</p> Signup and view all the answers

How do volatile anesthetic agents affect CNS opioid receptors?

<p>Increase opioid receptor density (B)</p> Signup and view all the answers

What compounds are non-depolarizing muscle relaxants structurally similar to?

<p>Curare (D)</p> Signup and view all the answers

Which muscle relaxant is commonly used for intubation or brief surgical procedures due to its rapid onset and short duration of action?

<p>Succinylcholine (D)</p> Signup and view all the answers

What is the effect of succinylcholine on skeletal muscles?

<p><strong>Depolarization</strong> (A)</p> Signup and view all the answers

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