18 Questions
What adverse effect is commonly associated with high-dose Ceftriaxone?
Diarrhea
Which antibiotic is known to cause harmless orange/red color changes in body fluids?
Ceftriaxone
What is the main mechanism of action of Metronidazole?
Disruption of DNA structure and function
Which antibiotic is commonly used to treat brain abscess caused by Toxoplasma gondii?
Trimethoprim-sulfamethoxazole
What is a common adverse effect associated with long-term use of Metronidazole?
Peripheral neuropathy
What treatment approach is recommended for a brain abscess caused by bacteria?
Combination of medical and surgical therapy
What is the mechanism of action of Amphotericin B?
Bind to ergosterol in fungal cell membranes and disrupt membrane permeability
Which drug is indicated for maintenance therapy for fungal meningitis?
Fluconazole
What is a major adverse effect associated with Flucytosine?
Renal toxicity
Which drug is used in combination with Amphotericin B for the treatment of fungal meningitis?
Flucytosine
What is the black box warning for Flucytosine?
Confusion and hallucinations
How does Flucytosine exert its antifungal effect?
Inhibit thymidylate synthesis
Which is the most common cause of bacterial meningitis in neonates?
Group B Streptococcus
What is the most appropriate antibiotic treatment for Streptococcus pneumoniae meningitis?
3rd generation cephalosporin + Vancomycin
What pathogen is associated with Gram-negative rod in bacterial meningitis?
Haemophilus influenzae
Which antibiotic is recommended for chemoprophylaxis in a household with unvaccinated kids?
Rifampin
What is the purpose of adjunctive corticosteroid therapy in treating meningitis?
To reduce hearing loss and mortality
What is the mechanism of action of 3rd generation cephalosporins in treating bacterial meningitis?
Inhibition of cell wall synthesis
Test your knowledge on drug interactions and side effects with this quiz covering topics such as ceftriaxone, warfarin, contraceptives, nephrotoxic drugs, QT prolonging drugs, and more.
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