Drug Interactions and Side Effects Quiz

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Questions and Answers

What adverse effect is commonly associated with high-dose Ceftriaxone?

  • Diarrhea (correct)
  • Renal toxicity
  • Hepatitis
  • Allergy

Which antibiotic is known to cause harmless orange/red color changes in body fluids?

  • Tetracyclines
  • Warfarin
  • Ceftriaxone (correct)
  • Metronidazole

What is the main mechanism of action of Metronidazole?

  • Inhibition of cell wall synthesis
  • Inhibition of protein synthesis
  • Disruption of DNA structure and function (correct)
  • Inhibition of RNA synthesis

Which antibiotic is commonly used to treat brain abscess caused by Toxoplasma gondii?

<p>Trimethoprim-sulfamethoxazole (D)</p> Signup and view all the answers

What is a common adverse effect associated with long-term use of Metronidazole?

<p>Peripheral neuropathy (A)</p> Signup and view all the answers

What treatment approach is recommended for a brain abscess caused by bacteria?

<p>Combination of medical and surgical therapy (C)</p> Signup and view all the answers

What is the mechanism of action of Amphotericin B?

<p>Bind to ergosterol in fungal cell membranes and disrupt membrane permeability (B)</p> Signup and view all the answers

Which drug is indicated for maintenance therapy for fungal meningitis?

<p>Fluconazole (B)</p> Signup and view all the answers

What is a major adverse effect associated with Flucytosine?

<p>Renal toxicity (A)</p> Signup and view all the answers

Which drug is used in combination with Amphotericin B for the treatment of fungal meningitis?

<p>Flucytosine (D)</p> Signup and view all the answers

What is the black box warning for Flucytosine?

<p>Confusion and hallucinations (A)</p> Signup and view all the answers

How does Flucytosine exert its antifungal effect?

<p>Inhibit thymidylate synthesis (B)</p> Signup and view all the answers

Which is the most common cause of bacterial meningitis in neonates?

<p>Group B Streptococcus (C)</p> Signup and view all the answers

What is the most appropriate antibiotic treatment for Streptococcus pneumoniae meningitis?

<p>3rd generation cephalosporin + Vancomycin (A)</p> Signup and view all the answers

What pathogen is associated with Gram-negative rod in bacterial meningitis?

<p>Haemophilus influenzae (C)</p> Signup and view all the answers

Which antibiotic is recommended for chemoprophylaxis in a household with unvaccinated kids?

<p>Rifampin (D)</p> Signup and view all the answers

What is the purpose of adjunctive corticosteroid therapy in treating meningitis?

<p>To reduce hearing loss and mortality (B)</p> Signup and view all the answers

What is the mechanism of action of 3rd generation cephalosporins in treating bacterial meningitis?

<p>Inhibition of cell wall synthesis (D)</p> Signup and view all the answers

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