Drug Interactions and Side Effects Quiz
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Questions and Answers

What adverse effect is commonly associated with high-dose Ceftriaxone?

  • Diarrhea (correct)
  • Renal toxicity
  • Hepatitis
  • Allergy

    • Which antibiotic is known to cause harmless orange/red color changes in body fluids?

  • Tetracyclines
  • Warfarin
  • Ceftriaxone (correct)
  • Metronidazole

    • What is the main mechanism of action of Metronidazole?

  • Inhibition of cell wall synthesis
  • Inhibition of protein synthesis
  • Disruption of DNA structure and function (correct)
  • Inhibition of RNA synthesis

    • Which antibiotic is commonly used to treat brain abscess caused by Toxoplasma gondii?

    <p>Trimethoprim-sulfamethoxazole</p> Signup and view all the answers

    What is a common adverse effect associated with long-term use of Metronidazole?

    <p>Peripheral neuropathy</p> Signup and view all the answers

    What treatment approach is recommended for a brain abscess caused by bacteria?

    <p>Combination of medical and surgical therapy</p> Signup and view all the answers

    What is the mechanism of action of Amphotericin B?

    <p>Bind to ergosterol in fungal cell membranes and disrupt membrane permeability</p> Signup and view all the answers

    Which drug is indicated for maintenance therapy for fungal meningitis?

    <p>Fluconazole</p> Signup and view all the answers

    What is a major adverse effect associated with Flucytosine?

    <p>Renal toxicity</p> Signup and view all the answers

    Which drug is used in combination with Amphotericin B for the treatment of fungal meningitis?

    <p>Flucytosine</p> Signup and view all the answers

    What is the black box warning for Flucytosine?

    <p>Confusion and hallucinations</p> Signup and view all the answers

    How does Flucytosine exert its antifungal effect?

    <p>Inhibit thymidylate synthesis</p> Signup and view all the answers

    Which is the most common cause of bacterial meningitis in neonates?

    <p>Group B Streptococcus</p> Signup and view all the answers

    What is the most appropriate antibiotic treatment for Streptococcus pneumoniae meningitis?

    <p>3rd generation cephalosporin + Vancomycin</p> Signup and view all the answers

    What pathogen is associated with Gram-negative rod in bacterial meningitis?

    <p>Haemophilus influenzae</p> Signup and view all the answers

    Which antibiotic is recommended for chemoprophylaxis in a household with unvaccinated kids?

    <p>Rifampin</p> Signup and view all the answers

    What is the purpose of adjunctive corticosteroid therapy in treating meningitis?

    <p>To reduce hearing loss and mortality</p> Signup and view all the answers

    What is the mechanism of action of 3rd generation cephalosporins in treating bacterial meningitis?

    <p>Inhibition of cell wall synthesis</p> Signup and view all the answers

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