Drug Interactions and Blood Glucose Quiz
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Questions and Answers

What is a potential effect of ACE inhibitors on blood glucose levels?

  • Increase insulin secretion
  • Inhibit hepatic glucose production (correct)
  • Delay insulin action
  • Block insulin secretion
  • Which medication is known to increase insulin secretion?

  • Fibrates
  • Alcohol
  • Phenobarbitone
  • Quinine (correct)
  • How do inducers of metabolism affect hypoglycemic drug concentration?

  • Have no effect
  • Increase it
  • Decrease it (correct)
  • Delay its action
  • Which drug is a known inhibitor of hepatic glucose production and release?

    <p>Salicylates</p> Signup and view all the answers

    What is a potential effect of Rifampicin on sulfonylurea concentrations?

    <p>Increase</p> Signup and view all the answers

    Which hormone is involved in the response to hypoglycemia by secretion of counter-regulatory hormones?

    <p>Glucagon</p> Signup and view all the answers

    Which of the following medications is likely to raise blood glucose levels?

    <p>Corticosteroids</p> Signup and view all the answers

    What is the probable mechanism by which thiazide diuretics affect blood glucose levels?

    <p>Opposing insulin action</p> Signup and view all the answers

    Which of the following drug classes is least likely to lower blood glucose levels?

    <p>Nifedipine</p> Signup and view all the answers

    How do phenothiazines mainly interact with blood glucose levels?

    <p>By impairing insulin secretion</p> Signup and view all the answers

    What effect do oral contraceptive hormones have on blood glucose levels?

    <p>They raise blood glucose levels by opposing insulin action</p> Signup and view all the answers

    In the context of drug interactions affecting blood glucose, which medication is most likely to have an adrenergic action contradicting insulin secretion?

    <p>Clonidine</p> Signup and view all the answers

    What is the mechanism of action of sulfonylureas on pancreatic beta cells?

    <p>Activation of KATP channels</p> Signup and view all the answers

    Which drug class is very similar to sulfonylureas in terms of mechanism and action?

    <p>Meglitinides</p> Signup and view all the answers

    What is the clinical relevance of meglitinides compared to sulfonylureas?

    <p>Longer half-life leading to less hypoglycemia</p> Signup and view all the answers

    Which ion channel is affected by sulfonylureas in the mechanism of action?

    <ul> <li>ATP-sensitive K+ channel</li> </ul> Signup and view all the answers

    What is the effect of sulfonylureas on the influx of calcium in pancreatic beta cells?

    <p>Increase influx of calcium</p> Signup and view all the answers

    How do meglitinides interact with sulfonylureas in terms of mechanism?

    <p>Induce the opposite effect on ATP-sensitive K+ channels</p> Signup and view all the answers

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