Drug Interactions and Blood Glucose Quiz

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What is a potential effect of ACE inhibitors on blood glucose levels?

Increase insulin secretion

Inhibit hepatic glucose production (correct)

Delay insulin action

Block insulin secretion

Which medication is known to increase insulin secretion?

Fibrates

Alcohol

Phenobarbitone

Quinine (correct)

How do inducers of metabolism affect hypoglycemic drug concentration?

Have no effect

Increase it

Decrease it (correct)

Delay its action

Which drug is a known inhibitor of hepatic glucose production and release?

Salicylates Signup and view all the answers

What is a potential effect of Rifampicin on sulfonylurea concentrations?

Increase Signup and view all the answers

Which hormone is involved in the response to hypoglycemia by secretion of counter-regulatory hormones?

Glucagon Signup and view all the answers

Which of the following medications is likely to raise blood glucose levels?

Corticosteroids Signup and view all the answers

What is the probable mechanism by which thiazide diuretics affect blood glucose levels?

Opposing insulin action Signup and view all the answers

Which of the following drug classes is least likely to lower blood glucose levels?

Nifedipine Signup and view all the answers

How do phenothiazines mainly interact with blood glucose levels?

By impairing insulin secretion Signup and view all the answers

What effect do oral contraceptive hormones have on blood glucose levels?

They raise blood glucose levels by opposing insulin action Signup and view all the answers

In the context of drug interactions affecting blood glucose, which medication is most likely to have an adrenergic action contradicting insulin secretion?

Clonidine Signup and view all the answers

What is the mechanism of action of sulfonylureas on pancreatic beta cells?

Activation of KATP channels Signup and view all the answers

Which drug class is very similar to sulfonylureas in terms of mechanism and action?

Meglitinides Signup and view all the answers

What is the clinical relevance of meglitinides compared to sulfonylureas?

Longer half-life leading to less hypoglycemia Signup and view all the answers

Which ion channel is affected by sulfonylureas in the mechanism of action?

<ul> <li>ATP-sensitive K+ channel</li> </ul> Signup and view all the answers

What is the effect of sulfonylureas on the influx of calcium in pancreatic beta cells?

Increase influx of calcium Signup and view all the answers

How do meglitinides interact with sulfonylureas in terms of mechanism?

Induce the opposite effect on ATP-sensitive K+ channels Signup and view all the answers