Podcast
Questions and Answers
What primary function is common to drug databases?
What primary function is common to drug databases?
- Supplying information on drug interactions, effects, and adverse reactions. (correct)
- Facilitating direct drug sales to consumers.
- Providing historical sales data for pharmaceutical companies.
- Tracking physician prescribing habits to prevent over-prescription.
Why is it important to check the published date on DailyMed when accessing package inserts?
Why is it important to check the published date on DailyMed when accessing package inserts?
- To confirm therapeutic equivalence to a brand-name drug.
- To ensure you have the most up-to-date information. (correct)
- To verify the insert has not been recalled by the FDA.
- To ensure the information is compliant with current advertising standards.
Which domain extension is most indicative of an educational institution?
Which domain extension is most indicative of an educational institution?
- .edu (correct)
- .gov
- .org
- .com
What is a key characteristic of a credible health information source?
What is a key characteristic of a credible health information source?
Why should information from forums, chat-rooms, and blogs be regarded cautiously?
Why should information from forums, chat-rooms, and blogs be regarded cautiously?
A website is advertising a 'quick' fix for a chronic condition. What 'red flag' does this represent?
A website is advertising a 'quick' fix for a chronic condition. What 'red flag' does this represent?
A researcher is studying the off-label uses of a particular medication. Which resource is LEAST likely to provide the needed information?
A researcher is studying the off-label uses of a particular medication. Which resource is LEAST likely to provide the needed information?
What is the primary purpose of the 'Trissel's IV Compatibility' tool within Lexicomp?
What is the primary purpose of the 'Trissel's IV Compatibility' tool within Lexicomp?
A healthcare provider needs to identify a medication using only a physical description of the pill. Which feature in Lexicomp would be MOST useful?
A healthcare provider needs to identify a medication using only a physical description of the pill. Which feature in Lexicomp would be MOST useful?
Which of the following resources is MOST suited for finding information on potential adverse effects of herbal supplements?
Which of the following resources is MOST suited for finding information on potential adverse effects of herbal supplements?
What is the MOST important factor to consider when using online package inserts?
What is the MOST important factor to consider when using online package inserts?
What type of question is MOST appropriately answered using Briggs Drugs in Pregnancy and Lactation?
What type of question is MOST appropriately answered using Briggs Drugs in Pregnancy and Lactation?
If a patient reports taking multiple herbal supplements, which database could MOST effectively identify potential interactions between them?
If a patient reports taking multiple herbal supplements, which database could MOST effectively identify potential interactions between them?
A researcher is conducting a meta-analysis of all published trials related to a novel cancer drug. Which resource would be MOST suitable for locating these studies?
A researcher is conducting a meta-analysis of all published trials related to a novel cancer drug. Which resource would be MOST suitable for locating these studies?
Which resource is best for identifying generic equivalents of brand-name drugs?
Which resource is best for identifying generic equivalents of brand-name drugs?
What is the significance of the 'Alert: U.S. Boxed Warning' section in a drug monograph?
What is the significance of the 'Alert: U.S. Boxed Warning' section in a drug monograph?
What is the primary difference between information found on Clinicaltrials.gov and information found in DailyMed?
What is the primary difference between information found on Clinicaltrials.gov and information found in DailyMed?
A patient is concerned about the excipients in their medication due to allergies. Which section of a drug resource would provide this information?
A patient is concerned about the excipients in their medication due to allergies. Which section of a drug resource would provide this information?
Which of the following criteria is LEAST important when evaluating the credibility of a drug information resource?
Which of the following criteria is LEAST important when evaluating the credibility of a drug information resource?
You are asked to assess if a new drug has a high risk of QTc prolongation. Which database would you consult FIRST?
You are asked to assess if a new drug has a high risk of QTc prolongation. Which database would you consult FIRST?
A 50 year old man presents with pneumonia and is candidate for antibiotics. According to Lexicomp what dose of Zosyn (piperacillin and tazobactam) would you recommend empirically?
A 50 year old man presents with pneumonia and is candidate for antibiotics. According to Lexicomp what dose of Zosyn (piperacillin and tazobactam) would you recommend empirically?
You have a 44-year-old female patient on intermittent hemodialysis who has developed atrial fibrillation and you would like to start her on Eliquis (apixaban). Her weight is 78 kg. According to Lexicomp, what dose of Eliquis (apixaban) would you recommend for her?
You have a 44-year-old female patient on intermittent hemodialysis who has developed atrial fibrillation and you would like to start her on Eliquis (apixaban). Her weight is 78 kg. According to Lexicomp, what dose of Eliquis (apixaban) would you recommend for her?
According to Lexicomp, what is the most common adverse reaction of varenicline?
According to Lexicomp, what is the most common adverse reaction of varenicline?
A nurse calls and asks if she can run lactated ringers and ceftriaxone together. According to Trissel's IV Compatibility, what infromation can you provide?
A nurse calls and asks if she can run lactated ringers and ceftriaxone together. According to Trissel's IV Compatibility, what infromation can you provide?
You run a drug interaction check in Lexicomp for simvastatin 40 mg, diltiazem 180 mg, and levothyroxine 75 mcg. What is the summary of the drug interaction between diltiazem and simvastatin?
You run a drug interaction check in Lexicomp for simvastatin 40 mg, diltiazem 180 mg, and levothyroxine 75 mcg. What is the summary of the drug interaction between diltiazem and simvastatin?
According to Natural Medicines, what are considered some of the most common adverse effects, if taken orally, of ginger?
According to Natural Medicines, what are considered some of the most common adverse effects, if taken orally, of ginger?
According to Natural Medicines, what are considered some of the most common adverse effects, if taken orally, of English Ivy?
According to Natural Medicines, what are considered some of the most common adverse effects, if taken orally, of English Ivy?
According to the FDA package insert reviewed, what safety considerations would you make for initiating dapagliflozin in an 85-year-old patient?
According to the FDA package insert reviewed, what safety considerations would you make for initiating dapagliflozin in an 85-year-old patient?
According to Lexicomp, what warning is associated with systemically administered clindamycin?
According to Lexicomp, what warning is associated with systemically administered clindamycin?
According to the package insert reviewed, what should be assessed before initiating FARXIGA?
According to the package insert reviewed, what should be assessed before initiating FARXIGA?
A 2-year-old presents to the emergency department with a rash spreading across their arms and trunk 30 minutes after taking their second dose of a medication with organic ivy leaf. According to Natural Medicines, what ingredient(s) could have caused this, if any?
A 2-year-old presents to the emergency department with a rash spreading across their arms and trunk 30 minutes after taking their second dose of a medication with organic ivy leaf. According to Natural Medicines, what ingredient(s) could have caused this, if any?
What type of information can be found in a drug package insert?
What type of information can be found in a drug package insert?
What is the role of the Food and Drug Administration (FDA) in relation to drug recalls?
What is the role of the Food and Drug Administration (FDA) in relation to drug recalls?
What type of information is MOST likely to be found in the Purple Book?
What type of information is MOST likely to be found in the Purple Book?
In addition to drug information, what other type of resource can be found in government databases like those from the National Library of Medicine?
In addition to drug information, what other type of resource can be found in government databases like those from the National Library of Medicine?
When evaluating drug information, what does 'validity' refer to?
When evaluating drug information, what does 'validity' refer to?
A website provides medical information but does not list the authors and their qualifications. What 'red flag' does this represent?
A website provides medical information but does not list the authors and their qualifications. What 'red flag' does this represent?
An online health resource consistently favors a particular brand of medication over others. Which potential issue does this highlight?
An online health resource consistently favors a particular brand of medication over others. Which potential issue does this highlight?
Which resource is most likely to contain information about the supply chain of a drug?
Which resource is most likely to contain information about the supply chain of a drug?
Flashcards
Drug databases
Drug databases
Help supply information on drug information, interactions, and adverse effects.
Quality (resources)
Quality (resources)
Degree or quality of evidence.
Validity (resources)
Validity (resources)
Founded on evidence or fact.
Credibility (resources)
Credibility (resources)
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.edu
.edu
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.gov
.gov
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.org
.org
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.com
.com
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Red Flags of Sources
Red Flags of Sources
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Lexicomp
Lexicomp
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Varenicline Adverse Effects
Varenicline Adverse Effects
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Lexicomp Trissel's IV Compatibility
Lexicomp Trissel's IV Compatibility
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Simvastatin and Diltiazem
Simvastatin and Diltiazem
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Package inserts
Package inserts
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Clindamycin Warning
Clindamycin Warning
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Study Notes
- Drug databases supply details on drug information, interactions, and adverse effects.
- Institutions offer resources, and the government provides numerous resources.
- Examples of government resources include the Food Drug Administration and the National Library of Medicine.
- The Food and Drug Administration provides the National Drug Code Directory, the Purple and Orange Book, MedWatch, and drug recalls.
- The National Library of Medicine includes PubMed, Clinicaltrials.gov, DailyMed, and Centers for Disease Control.
Evaluation of resources encompass these qualities:
- Quality = Degree or quality of evidence.
- Validity = Founded on evidence or fact.
- Credibility = The quality of being trusted and believed in.
- .edu = Educational institution.
- .gov = Governmental organizations.
- .org = Nonprofit organization.
- .com = For-profit company.
Red Flags of Sources
- Anonymous or no listed author is a red flag
- Conflict of interest suggests bias is a source.
- Outdated or not dated sources are not credible.
- Claims of a 'quick' fix or 'secret cure' are dubious and not fact checked.
- The lack of references signifies non-credible information.
- Poor grammar, spelling, etc lowers confidence.
- Forums, chat-rooms, blogs, and bulletin boards are red flags.
- Asking for personal information is a serious red flag.
- Package inserts are always FREE (ensure it is the latest version!)
Drug Resources
- Resources vary at each institution.
- Available drug resources include Lexicomp, Clinical Pharmacology/ToxED, Pubmed, Micromedex, Natural Medicines, Briggs Drugs in Pregnancy and Lactation, NeoFax - Pediatrics Resource, and Reprotox - Pregnancy resources.
- The UNM HSC Library website offers access to UNM resources.
Lexicomp
- Lexicomp includes information for pediatric, breastfeeding, and pregnant patients.
- The most common adverse reaction of varenicline is nausea.
- Trissel's IV Compatibility indicates which drugs are compatible with IV lines.
- The Drug-Drug interaction checker assesses possible combinations
Natural Medicines
- Natural Medicines is a resource available on dietary supplements, natural medicines, and complementary alternative and integrative therapies.
- Orally, ginger is generally well tolerated.
- Higher ginger doses of 5 grams daily increase the risk of adverse effects/reduce tolerability.
- Topically, ginger seems well tolerated.
- Orally, ginger can cause hives as well as bruising, flushing, or rash.*
- *Dermatologic: Orally ,English ivy and fresh English ivy leaves can cause skin irritation
Package Inserts
- Manufacture publishes drug information.
- Package inserts are available via DailyMed.
- Old versions can exist, so verify the published date.
- Systemically administered clindamycin carries a warning for Clostridium difficile associated diarrhea (CDAD).
Takeaways
- Drug databases are helpful tools to help with known drug information.
- Quality, credibility, and validity play a role in assess the database information.
- Lexicomp, natural medicines.
- Evaluate drug-related questions to determine the most appropriate database or resource for obtaining accurate information.
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