15 Questions
What is pigmentation defined as?
The process of deposition of pigments in oral tissue
What is the term for cells responsible for producing melanin?
Melanocytes
What is hyperpigmentation caused by?
The deposition of excessive pigments in oral tissue
What is the result of excessive melanin production?
Hyperpigmentation
What is the role of melanocytes in oral tissue?
To produce melanin
What is thought to stimulate an increase in melanin production in the basal cell layer of the epithelium, leading to oral hyperpigmentation?
Exposure to tobacco
What type of pigmentation is characterized by blotchy pigmentation on the face and nipples during pregnancy?
Physiological pigmentation
In which population is basilar melanosis more common?
Individuals of African descent
What is the term for the pigmentation that occurs in response to hormonal changes during pregnancy?
Melasma
What is the term for the increased melanin production in the basal cell layer of the epithelium?
Basilar melanosis
What is the main cause of oral post-inflammatory pigmentation?
Excess of melanin production and deposition
What layer of the epithelium is affected by oral post-inflammatory pigmentation?
Basal layer
What is the term for the discoloration of the oral mucosa caused by an excess of melanin production and deposition?
Oral post-inflammatory pigmentation
What is the result of an excess of melanin production and deposition in the oral mucosa?
Discoloration of the oral mucosa
What is the term for drug-induced hyperpigmentation that affects the oral mucosa?
Oral post-inflammatory pigmentation
Study Notes
Drug-Induced Hyperpigmentation
- Oral post-inflammatory pigmentation (OPP) is a discoloration of the oral mucosa caused by an excess of melanin production and deposition within the basal layer of the epithelium.
Pigmentation
- Pigmentation is defined as the process of deposition of pigments in oral tissue.
- Types of pigments that may cause hyperpigmentation include:
- Melanin
Melanocytes
- Melanocytes are responsible for melanin production.
Etiology
- The lesion is thought to represent an increase in melanin production in the basal cell layer of the epithelium stimulated by tobacco.
Physiological Pigmentation
- Racial pigmentation: melanin is present in the basal cell layer of epithelium in people of African descent (basilar melanosis).
- Pregnancy-related pigmentation: blotchy pigmentation on the face, nipples (melasma).
Test your knowledge on drug-induced hyperpigmentation, a condition characterized by excessive melanin production and deposition in the oral mucosa.
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