Podcast
Questions and Answers
What branch of pharmacology deals with the undesirable effects of chemicals on living systems?
What branch of pharmacology deals with the undesirable effects of chemicals on living systems?
What should all dietary supplements and health therapies meet in terms of standards?
What should all dietary supplements and health therapies meet in terms of standards?
Which area of study in pharmacology is focused on understanding the actions of drugs on individual organisms?
Which area of study in pharmacology is focused on understanding the actions of drugs on individual organisms?
What are the two large domains into which the actions of chemicals can be divided?
What are the two large domains into which the actions of chemicals can be divided?
Signup and view all the answers
How do the chemicals in botanicals differ from those in manufactured drugs?
How do the chemicals in botanicals differ from those in manufactured drugs?
Signup and view all the answers
What does pharmacodynamics primarily concern?
What does pharmacodynamics primarily concern?
Signup and view all the answers
What are the three main ways a drug should be eliminated from the body?
What are the three main ways a drug should be eliminated from the body?
Signup and view all the answers
Why are special carrier molecules important for some substances important for cell function?
Why are special carrier molecules important for some substances important for cell function?
Signup and view all the answers
What distinguishes special carrier molecules from passive diffusion?
What distinguishes special carrier molecules from passive diffusion?
Signup and view all the answers
Which family of transporters binds adenosine triphosphate (ATP)?
Which family of transporters binds adenosine triphosphate (ATP)?
Signup and view all the answers
What is a common mechanism for drug permeation?
What is a common mechanism for drug permeation?
Signup and view all the answers
How can drug vehicles facilitate drug transport?
How can drug vehicles facilitate drug transport?
Signup and view all the answers
What type of substances are stored in membrane-bound vesicles in nerve endings to protect them from metabolic destruction?
What type of substances are stored in membrane-bound vesicles in nerve endings to protect them from metabolic destruction?
Signup and view all the answers
What determines the mobility of drug molecules in the medium of the diffusion path?
What determines the mobility of drug molecules in the medium of the diffusion path?
Signup and view all the answers
Which form of a weak acid will be more lipid-soluble at acid pH?
Which form of a weak acid will be more lipid-soluble at acid pH?
Signup and view all the answers
What is responsible for the secretion of many substances from cells?
What is responsible for the secretion of many substances from cells?
Signup and view all the answers
What does Fick's Law of Diffusion describe?
What does Fick's Law of Diffusion describe?
Signup and view all the answers
How does the lipid:aqueous partition coefficient impact the mobility of a drug?
How does the lipid:aqueous partition coefficient impact the mobility of a drug?
Signup and view all the answers
What is pharmacology defined as?
What is pharmacology defined as?
Signup and view all the answers
Who were pioneers in developing experimental physiology and pharmacology in the late 18th and early 19th centuries?
Who were pioneers in developing experimental physiology and pharmacology in the late 18th and early 19th centuries?
Signup and view all the answers
Which type of molecules do small interfering RNAs (siRNAs) and micro-RNAs (miRNAs) target for therapeutic effects?
Which type of molecules do small interfering RNAs (siRNAs) and micro-RNAs (miRNAs) target for therapeutic effects?
Signup and view all the answers
What do antisense oligonucleotides (ANOs) interfere with?
What do antisense oligonucleotides (ANOs) interfere with?
Signup and view all the answers
What does pharmacology study in relation to living systems?
What does pharmacology study in relation to living systems?
Signup and view all the answers
What is the main focus of pharmacology in relation to patients?
What is the main focus of pharmacology in relation to patients?
Signup and view all the answers
What drives the movement of drug molecules according to Fick’s law?
What drives the movement of drug molecules according to Fick’s law?
Signup and view all the answers
Which factor influences the flux of charged drugs in addition to the concentration gradient?
Which factor influences the flux of charged drugs in addition to the concentration gradient?
Signup and view all the answers
Where do drug molecules permeate across in the body, besides larger aqueous compartments?
Where do drug molecules permeate across in the body, besides larger aqueous compartments?
Signup and view all the answers
Which transporter is found in the brain, testes, and some drug-resistant neoplastic cells?
Which transporter is found in the brain, testes, and some drug-resistant neoplastic cells?
Signup and view all the answers
What does the Henderson-Hasselbalch equation express for a weak acid or weak base?
What does the Henderson-Hasselbalch equation express for a weak acid or weak base?
Signup and view all the answers
How does the pH of the medium affect the movement of weak acids and weak bases between aqueous and lipid media?
How does the pH of the medium affect the movement of weak acids and weak bases between aqueous and lipid media?
Signup and view all the answers