Podcast
Questions and Answers
What is the primary mechanism by which antibiotic medications interact with warfarin to increase the risk of major bleeding?
What is the primary mechanism by which antibiotic medications interact with warfarin to increase the risk of major bleeding?
- Enhanced production of platelets
- Increase in sensitivity of hepatic receptors to warfarin
- Disruption of intestinal flora that synthesize Vitamin K (correct)
- Inhibition of Cytochrome p450 isozymes which metabolize warfarin
What is the preferred range of INR levels for a patient on anticoagulation therapy?
What is the preferred range of INR levels for a patient on anticoagulation therapy?
- 3 - 4
- 1.5 - 2.5
- 2 - 3 (correct)
- 2.5 - 3.5
What is the preferred range of INR levels for a patient on anticoagulation therapy?
What is the preferred range of INR levels for a patient on anticoagulation therapy?
- 0.5 - 1.5
- 2 - 3 (correct)
- 3.5 - 4.5
- 5 - 6
Which of the following antibiotic medications is NOT associated with an increased risk of bleeding when interacting with warfarin?
Which of the following antibiotic medications is NOT associated with an increased risk of bleeding when interacting with warfarin?
What type of medication are Azole Antifungals (e.g., Fluconazole, Itraconazole) and Miconazole?
What type of medication are Azole Antifungals (e.g., Fluconazole, Itraconazole) and Miconazole?
Which of the following mechanisms is NOT a primary reason for the interaction between antibiotic medications and warfarin, leading to an increased risk of major bleeding?
Which of the following mechanisms is NOT a primary reason for the interaction between antibiotic medications and warfarin, leading to an increased risk of major bleeding?
What is the purpose of monitoring INR closely during and after antimicrobial treatment?
What is the purpose of monitoring INR closely during and after antimicrobial treatment?
What is the purpose of adjusting the dose of warfarin based on periodic blood tests?
What is the purpose of adjusting the dose of warfarin based on periodic blood tests?
Which class of medication do Azole Antifungals (e.g., Fluconazole, Itraconazole) and Miconazole belong to?
Which class of medication do Azole Antifungals (e.g., Fluconazole, Itraconazole) and Miconazole belong to?
What is the primary effect of monitoring INR closely during and after antimicrobial treatment?
What is the primary effect of monitoring INR closely during and after antimicrobial treatment?
