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Questions and Answers
What primarily influences the phase of drug distribution?
What primarily influences the phase of drug distribution?
- Drug metabolism
- Blood flow to tissues (correct)
- Drug elimination
- Drug formulation
Drug protein binding affects distribution by:
Drug protein binding affects distribution by:
- Increasing drug solubility
- Reducing the amount of free drug available (correct)
- Enhancing drug efficacy
- Accelerating drug metabolism
A loading dose is typically used to:
A loading dose is typically used to:
- Maintain therapeutic levels over time
- Increase drug metabolism
- Reduce side effects
- Achieve therapeutic levels quickly (correct)
What is the primary purpose of a maintenance dose in pharmacotherapy?
What is the primary purpose of a maintenance dose in pharmacotherapy?
The plasma drug level refers to:
The plasma drug level refers to:
The time course of a drug response is influenced by:
The time course of a drug response is influenced by:
Pharmacodynamics primarily studies:
Pharmacodynamics primarily studies:
Efficacy refers to:
Efficacy refers to:
The drug dose-response relationship describes:
The drug dose-response relationship describes:
An agonist is defined as:
An agonist is defined as:
Which statement accurately describes the action of a drug antagonist?
Which statement accurately describes the action of a drug antagonist?
The affinity of a drug for its receptor indicates:
The affinity of a drug for its receptor indicates:
The therapeutic index is:
The therapeutic index is:
The primary site of drug metabolism in the body is:
The primary site of drug metabolism in the body is:
Effective drug metabolism generally results in:
Effective drug metabolism generally results in:
Which of the following can influence drug metabolism?
Which of the following can influence drug metabolism?
Drug excretion primarily occurs through:
Drug excretion primarily occurs through:
Peak concentration refers to:
Peak concentration refers to:
In older adults, pharmacokinetic changes may include:
In older adults, pharmacokinetic changes may include:
Common causes of adverse drug reactions in older adults include:
Common causes of adverse drug reactions in older adults include:
The Beers List is designed to:
The Beers List is designed to:
Factors contributing to non-adherence in older adults may include:
Factors contributing to non-adherence in older adults may include:
Measures to promote adherence with drug treatment plans in older adults include:
Measures to promote adherence with drug treatment plans in older adults include:
Study Notes
Drug Distribution
- Drug protein binding influences drug distribution by affecting the amount of drug that is free to interact with tissues and exert its effects.
- A loading dose is used to rapidly achieve therapeutic drug concentrations.
- The maintenance dose is used to maintain the therapeutic drug concentration over time.
- Plasma drug level refers to the concentration of a drug in the blood.
- The time course of drug response is influenced by factors like absorption, distribution, metabolism, and excretion.
- Pharmacodynamics studies the effects of drugs on the body.
- Efficacy refers to the maximal effect a drug can produce.
- The drug dose-response relationship describes the correlation between the dose of a drug and the magnitude of its effect.
- An agonist is a drug that binds to a receptor and activates it.
- An antagonist blocks the action of an agonist by preventing it from binding to its receptor, or by binding to the receptor without activating it.
- Drug affinity for its receptor indicates how strongly the drug binds to the receptor.
- The therapeutic index is a measure of the safety of a drug.
- The primary site of drug metabolism in the body is the liver.
- Drug metabolism generally results in the formation of inactive metabolites that can be excreted from the body.
- Drug metabolism can be influenced by factors like age, genetics, and disease.
- Drug excretion primarily occurs through the kidneys.
- Peak concentration refers to the highest concentration of a drug in the blood after administration.
- In older adults, pharmacokinetic changes may include decreased renal function, decreased hepatic metabolism, and increased body fat.
- Common causes of adverse drug reactions in older adults include polypharmacy, drug interactions, and age-related changes in drug metabolism and excretion.
- The Beers List is designed to identify medications that are potentially inappropriate for older adults.
- Factors contributing to non-adherence in older adults may include forgetfulness, difficulty understanding instructions, and concerns about side effects.
- Measures to promote adherence with drug treatment plans in older adults include simplifying medication regimens, providing clear instructions, and involving family members in the care process.
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Explore the key factors that influence the phase of drug distribution in the body. This quiz will test your understanding of the physiological and chemical properties that affect how drugs are distributed, absorbed, and metabolized. Perfect for students and professionals in pharmacology or related fields.
