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Questions and Answers
What are barbiturates primarily used for?
What are barbiturates primarily used for?
- Long-term treatment of insomnia
- Short-term treatment of insomnia (correct)
- Surgery
- Chronic pain management
Barbiturates are commonly prescribed for chronic insomnia.
Barbiturates are commonly prescribed for chronic insomnia.
False (B)
What is the most frequently used barbiturate as a hypnotic?
What is the most frequently used barbiturate as a hypnotic?
Phenobarbital
What is the mechanism of action of barbiturates?
What is the mechanism of action of barbiturates?
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Which barbiturate is used as an anesthetic agent?
Which barbiturate is used as an anesthetic agent?
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Name the barbiturates more commonly used in the operating room.
Name the barbiturates more commonly used in the operating room.
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What substances interact negatively with barbiturates?
What substances interact negatively with barbiturates?
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Study Notes
Barbiturates Overview
- Barbiturates are infrequently prescribed for insomnia, primarily suited for short-term use (up to 2 weeks).
- Their utilization is limited due to side effects, notably the potential for drug tolerance.
Insomnia Treatment
- Barbiturates can treat insomnia but are not commonly used for chronic cases due to the availability of less potent alternatives.
Commonly Used Barbiturates
- Phenobarbital is the most frequently used barbiturate as a hypnotic agent.
Administration of Phenobarbital
- Available via intravenous (IV) or oral (PO) routes.
- Continuous infusion is rare in practice.
Mechanism of Action
- Barbiturates enhance the effects of GABA, the primary inhibitory neurotransmitter, leading to a depression of CNS activity.
Secobarbital Usage
- Primarily utilized as an anesthetic agent during infusion.
Barbiturates in the Operating Room
- Commonly used barbiturates include phenobarbital, pentobarbital, and secobarbital, frequently administered in surgical settings.
Drug Interactions
- Barbiturates interact with various substances, particularly:
- Alcohol
- Opioids
- Other sedative hypnotics
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