PH 3 Principles of Pharmacology

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Which of the following terms refers to drugs that work by activating or unlocking cell receptors causing the same actions as the body's own chemicals?

Agonist

Which term refers to the severe symptoms or problems that can cause great harm?

Anaphylactic reaction

What term describes drug products that are chemically the same or identical?

Bioequivalent

What term refers to the transformation or altering of a drug into either active or inactive chemicals after it has been absorbed?

Biotransformation

Which of the following is NOT a basic process involved in drug utilization in the body?

Excretion

Which of the following is NOT a mechanism of absorption?

Dissolution

Which route of administration delivers drugs directly into the bloodstream?

Intravenous route

Which route of administration has the slowest onset of drug absorption?

Oral route

Which term refers to the movement of a drug in the body to reach its site of action by way of the blood and lymph system?

Distribution

What is the term for when one drug changes the action of another drug?

Drug interaction

What is the term for adverse drug effects that can result in liver damage?

Hepatotoxic

What is the term for the time it takes the body to remove 50% of the drug from the body?

Half-life

Which of the following is the generic name for Valium?

Diazepam

Which organization assigns generic names to drugs?

US Adopted Names Council

Which type of drug name is often descriptive, easy to spell, and used in advertisements?

Trade name

What is the chemical name for meperidine (Demerol)?

Ethyl 1-methyl-4phenylisonipecotate hydrochloride

Which organ is mainly responsible for the biotransformation of drugs in the body?

Liver

Which of the following factors can affect the distribution of a drug in the body?

Body weight

What happens to inactive chemicals, by-products, and waste in the body?

They are metabolized and excreted

What is the purpose of the cytochrome P-450 system in the liver?

To break down drugs into usable parts

Which process is important to understand in order to identify when patients may have toxic or ill effects of drugs on the body?

Metabolism

What is the half-life of a drug?

The time it takes for the drug to be completely removed from the body

Why is it important to monitor patients closely after they take a drug?

To identify any side effects or adverse reactions

What are side effects of a drug?

Mild but annoying responses to the drug

Which term is used to describe strange, unique, or unpredicted responses to drugs?

Idiosyncratic responses

What is the term for a type of idiosyncratic response where the patient's reaction is the opposite of what would be expected?

Paradoxical response

Which organ(s) are mentioned as being at risk of damage from certain drugs?

Both kidney and liver

What is the term for severe adverse effects that may require the drug to be stopped?

Adverse reactions

Which antihistamine is mentioned as having sedative effects but may cause a paradoxical response in some individuals?

Diphenhydramine (Benadryl)

What is the term for a drug reaction that is a surprise?

Unexpected response

Which of the following is the correct expression for the given equation?

$3^{-2} + 2$

Which of the following is NOT a process involved in drug utilization in the body?

Absorption

Which of the following is an example of an antagonist?

Narcan (naloxone)

Which mechanism of absorption involves the diffusion of fluid through a semipermeable membrane?

Osmosis

Which route of administration delivers drugs directly into the bloodstream?

Intravenous

Which of the following terms refers to drugs that attach at a drug receptor site but do not activate or unlock the receptor?

Antagonist

Which of the following terms refers to the transformation or altering of a drug into either active or inactive chemicals after it has been absorbed?

Biotransformation

Which of the following terms refers to drug products that are chemically the same or identical?

Bioequivalent

Which of the following terms refers to severe symptoms or problems that can cause great harm?

Adverse reaction

Which term refers to the name given to a drug before there is any specific trade name or when the drug has been available for many years and more than one company makes the drug?

Generic name

What is the term for drugs that attach to the receptor site but produce only a partial effect?

Partial agonists

Which organization assigns generic names to drugs?

The US Adopted Names Council

What is the term for drugs that attach at a drug receptor site but do not activate or unlock it, blocking the action of agonists?

Receptor antagonists

Which organ is primarily responsible for the biotransformation of drugs in the body?

Liver

Which process is responsible for the distribution of drugs in the body?

Distribution

What happens to inactive chemicals, by-products, and waste in the body?

They are passed through the gastrointestinal tract

Which term refers to the process of transforming a prodrug into an active form of the drug?

Biotransformation

Which of the following processes is important to understand in order to identify when patients may have toxic or ill effects of drugs on the body?

Metabolism

What is the term for the time it takes the body to remove 50% of a drug from the body?

Half-life

Which of the following is a common side effect of drugs that work by activating or unlocking cell receptors causing the same actions as the body's own chemicals?

Sleepiness

Why is it important to monitor patients closely after they take a drug?

To watch for unexpected chemical reactions and side effects

Which term refers to the unexpected, unique, or unpredictable responses to drugs that may be caused by genetic or hormonal variations in an individual?

Idiosyncratic response

What is the term for adverse drug effects that can cause damage to the liver?

Hepatotoxic effects

Which organ is at risk of damage from certain drugs, such as nephrotoxic or hepatotoxic drugs?

Kidney

Which type of drug reaction is characterized by the patient's reaction being the opposite of what would be expected?

Paradoxical response

What is the term for the severe adverse effects of a drug that may require the drug to be stopped?

Discontinuation effects

What is the term for the movement of a drug in the body to reach its site of action through the blood and lymph system?

Distribution

Which of the following terms refers to drugs that work by activating or unlocking cell receptors causing the same actions as the body's own chemicals?

Agonists

Which of the following terms refers to drug products that are chemically the same or identical?

Bioequivalent

Which of the following terms refers to the transformation or altering of a drug into either active or inactive chemicals after it has been absorbed?

Biotransformation

Which of the following terms refers to severe symptoms or problems that can cause great harm?

Adverse reactions

Which of the following is NOT a type of drug name mentioned in the text?

Brand name

What is the term for drugs that activate or unlock cell receptors causing the same actions as the body's own chemicals?

Agonists

Which of the following is an example of a partial agonist?

Buspirone

What is the term for a drug that attaches at a drug receptor site but does not activate or unlock it?

Antagonist

Which of the following mechanisms is involved in drug absorption through diffusion?

Filtration

Which of the following routes of administration has the fastest onset of drug absorption?

Intravenous (IV)

Which of the following terms refers to drugs that attach at a drug receptor site but do not activate or unlock the receptor?

Antagonist

Which of the following processes is involved in drug utilization in the body?

Metabolism

Which of the following terms refers to the process of transforming a prodrug into an active form of the drug?

Biotransformation

What is the term for severe adverse effects that may require the drug to be stopped?

Adverse reactions

What is the term for a type of idiosyncratic response where the patient's reaction is the opposite of what would be expected?

Paradoxical response

What is the term for drugs that attach to the receptor site but produce only a partial effect?

Partial agonists

Which of the following factors can lead to uneven distribution of a drug in the body?

All of the above

Where does biotransformation of drugs mainly occur in the body?

Liver

Which organ is primarily responsible for the excretion of drugs from the body?

Kidneys

What is the term for the buildup of a drug in fat tissue, leading to a prolonged effect?

Storage

Which term refers to the strange, unique, peculiar, or unpredicted responses to drugs that may be the result of missing or defective metabolic enzymes caused by a genetic or hormonal variation of an individual?

Idiosyncratic responses

Which term refers to a type of idiosyncratic response where the patient's reaction may be just the opposite of what would be expected?

Paradoxical responses

Which antihistamine is mentioned as having sedative (sleep-inducing) effects but may cause a paradoxical response in some individuals?

Diphenhydramine (Benadryl)

What is the term for the severe adverse effects of a drug that may require the drug to be stopped?

Adverse reactions

Which one of these is NOT a potential organ affected by severe adverse effects of drugs?

Lung

What is the term for the movement of a drug in the body to reach its site of action by way of the blood and lymph system?

Distribution

Which of the following is the equation of a line in slope-intercept form?

$y = mx + b$

Which of the following is the formula for the area of a circle?

$A = \pi r^2$

Which of the following is the quadratic formula?

$x = \frac{-b \pm \sqrt{b^2 - 4ac}}{2a}$

Which of the following is the formula for the volume of a rectangular prism?

$V = lwh$

Which of the following is the Pythagorean theorem?

$c^2 = a^2 + b^2$

Which of the following processes is involved in drug utilization in the body?

Absorption

Which of the following mechanisms is involved in drug absorption?

All of the above

Which route of administration delivers drugs directly into the bloodstream?

Intravenous route

Which of the following processes involves the movement of a drug in the body to reach its site of action?

Distribution

Which of the following terms refers to drugs that work by activating or unlocking cell receptors causing the same actions as the body's own chemicals?

Agonist

What is the term for the severe symptoms or problems that can cause great harm?

Adverse reaction

Which term is used to describe the transformation or altering of a drug into either active or inactive chemicals after it has been absorbed?

Biotransformation

What is the term for drugs that attach at a drug receptor site but do not activate or unlock the receptor, blocking the action of agonists?

Antagonist

Which process is primarily responsible for transforming drugs into active or inactive chemicals in the body?

Metabolism

What is the term for the movement of drugs from the stomach or small intestines to the liver, where a lot of the drug is inactivated before it can be distributed to other parts of the body?

First pass effect

Which organ plays a major role in the biotransformation of drugs in the body?

Liver

Which of the following is NOT a route of drug excretion from the body?

Gastrointestinal tract

Which of the following processes is important to understand in order to identify when patients may have toxic or ill effects of drugs on the body?

Metabolism

What is the term for the time it takes for the body to remove 50% of a drug from the body?

Half-life

What are the expected, usually mild but annoying, responses to a drug called?

Side effects

Which of the following is an example of a severe symptom or problem that can develop because of a drug?

Steven-Johnsons syndrome

Which term refers to the name given to a drug before there is any specific trade name or when the drug has been available for many years and more than one company makes the drug?

Generic name

Which of the following organizations assigns generic names to drugs?

All of the above

Which of the following terms refers to the drug name used in advertisements and is often descriptive, easy to spell, or catchy sounding so that prescribers will remember it easily and be more likely to use it?

Trade name

Which of the following terms refers to drugs that attach at a drug receptor site but do not activate or unlock the receptor, blocking the action of agonists?

Antagonists

Which of the following is the equation for a straight line?

$y = 3x - 2$

What is the area of a rectangle with length 6 cm and width 4 cm?

24 cm

Simplify the expression $3(2x - 5) + 4(3x + 1)$

$18x - 7$

What is the value of $x$ in the equation $2x + 5 = 15$?

$x = 10$

Which of the following is the formula for the area of a circle?

$A = \pi r^2$

Which term refers to the strange, unique, or unpredicted responses to drugs that may be the result of missing or defective metabolic enzymes caused by a genetic or hormonal variation of an individual?

Idiosyncratic responses

Which organ is at risk of damage from certain drugs, such as nephrotoxic or hepatotoxic drugs?

Kidney

Which type of idiosyncratic response is characterized by the patient's reaction being just the opposite of what would be expected?

Paradoxical response

Which antihistamine is mentioned as having sedative (sleep-inducing) effects but may cause a paradoxical response in some individuals?

Diphenhydramine (Benadryl)

What term refers to the severe adverse effects of a drug that may require the drug to be stopped?

Adverse reaction

Which term refers to drugs that attach at a drug receptor site but do not activate or unlock the receptor?

Antagonists

Identifying and Managing Drug Adverse Reactions: Test your knowledge on recognizing and handling unexpected drug reactions as a nurse. Learn how to identify signs of nephrotoxicity, hepatotoxicity, and bleeding, and understand the role of nurses in ensuring patient well-being. Get ready to tackle unique and peculiar drug reactions with confidence!

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