Drug Administration Routes Quiz

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Questions and Answers

Which route of drug administration is most likely to lead to the first-pass effect?

  • Inhalation
  • Intravenous
  • Subcutaneous
  • Oral (correct)

Rectal suppositories intended for adult use usually weigh approximately:

  • 2mg
  • 20g
  • 10mg
  • 5g (correct)

After peroral administration, drugs generally are absorbed best from the?

  • Rectum
  • Small intestine (correct)
  • Large intestine
  • Stomach

Which of the following routes have the highest bioavailability?

<p>Intravenous (A)</p> Signup and view all the answers

Vanishing cream is an ointment that may be classified as?

<p>Water-soluble base (C)</p> Signup and view all the answers

Nitroglycerine is administered by which route?

<p>Sublingual (D)</p> Signup and view all the answers

What is the principle site of drug absorption for a drug given orally?

<p>Small intestine (C)</p> Signup and view all the answers

What is the daily dose of papaverine hydrochloride if a patient is prescribed an intramuscular injection of a 2% solution 1 ml 2 times a day?

<p>0.5 g per day (A)</p> Signup and view all the answers

From which dosage form does a drug, when taken orally, absorb and enter the bloodstream faster?

<p>Capsule filled with liquid (D)</p> Signup and view all the answers

Which of the following is a phase II drug-metabolizing reaction?

<p>Glucuronidation (C)</p> Signup and view all the answers

With which method of administration is the bioavailability of the drug 100%?

<p>Intravenous (D)</p> Signup and view all the answers

What is pharmacokinetics the study of?

<p>Absorption, distribution, metabolism, excretion (C)</p> Signup and view all the answers

What characterizes the indicator of pharmacokinetics known as clearance?

<p>Rate at which drug is removed from the plasma relative to its concentration in the plasma (D)</p> Signup and view all the answers

8

<p>Liver (B)</p> Signup and view all the answers

Which functional group is most susceptible to hydrolysis?

<p>Ester group (A)</p> Signup and view all the answers

What does the volume of distribution (Vd) relate to?

<p>The amount of drug in body to concentration of drug in plasma (C)</p> Signup and view all the answers

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