Drug Administration Routes Quiz
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Questions and Answers

Which route of drug administration is most likely to lead to the first-pass effect?

  • Inhalation
  • Intravenous
  • Subcutaneous
  • Oral (correct)
  • Rectal suppositories intended for adult use usually weigh approximately:

  • 2mg
  • 20g
  • 10mg
  • 5g (correct)
  • After peroral administration, drugs generally are absorbed best from the?

  • Rectum
  • Small intestine (correct)
  • Large intestine
  • Stomach
  • Which of the following routes have the highest bioavailability?

    <p>Intravenous</p> Signup and view all the answers

    Vanishing cream is an ointment that may be classified as?

    <p>Water-soluble base</p> Signup and view all the answers

    Nitroglycerine is administered by which route?

    <p>Sublingual</p> Signup and view all the answers

    What is the principle site of drug absorption for a drug given orally?

    <p>Small intestine</p> Signup and view all the answers

    What is the daily dose of papaverine hydrochloride if a patient is prescribed an intramuscular injection of a 2% solution 1 ml 2 times a day?

    <p>0.5 g per day</p> Signup and view all the answers

    From which dosage form does a drug, when taken orally, absorb and enter the bloodstream faster?

    <p>Capsule filled with liquid</p> Signup and view all the answers

    Which of the following is a phase II drug-metabolizing reaction?

    <p>Glucuronidation</p> Signup and view all the answers

    With which method of administration is the bioavailability of the drug 100%?

    <p>Intravenous</p> Signup and view all the answers

    What is pharmacokinetics the study of?

    <p>Absorption, distribution, metabolism, excretion</p> Signup and view all the answers

    What characterizes the indicator of pharmacokinetics known as clearance?

    <p>Rate at which drug is removed from the plasma relative to its concentration in the plasma</p> Signup and view all the answers

    8

    <p>Liver</p> Signup and view all the answers

    Which functional group is most susceptible to hydrolysis?

    <p>Ester group</p> Signup and view all the answers

    What does the volume of distribution (Vd) relate to?

    <p>The amount of drug in body to concentration of drug in plasma</p> Signup and view all the answers

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