Drosophila Wing Development Quiz

Embryonic ectoderm structures that remain until metamorphosis and develop into specific adult structures.

Genes that determine the body plan of an organism during development, such as deciding segments.

Protein gradient in Drosophila wing that helps pattern the wing along the anterior-posterior axis.

A special region that sets up signals to direct development of structures like the wing of a fly.

A protein that controls genes needed specifically for wing development.

The process of establishing the front-to-back axis in developing organs.

A signaling molecule that establishes a concentration gradient, directing cell behavior.

Genes that are always on and set the stage for other genes to turn on to generate a specific part of the body.

The combination of Hox genes expressed in the lateral plate mesoderm determines whether a forelimb or hindlimb develops. Tbx5 is activated for forelimbs, while Tbx4 is activated for hindlimbs.

The Apical Ectodermal Ridge (AER) is a signaling center located at the tip of the limb bud. It is crucial for proximo-distal development, meaning the development of the limb from shoulder to fingertips.

Fibroblast Growth Factors (FGFs) are signaling molecules that play a crucial role in limb development. FGF10 and FGF8 are key players in the formation of the AER.

The polarizing region is located on the posterior side of the limb bud. It is essential for A-P patterning, meaning the development of the limb along the anterior-posterior axis (thumb to pinky).

If the AER is removed, the limb will develop only up to the point where the AER was removed, resulting in limb truncation. This demonstrates that the AER is essential for proximo-distal development and limb growth.

A transcription factor essential for correct wing development in Drosophila, meaning without it, normal wings won't form. It works by interacting with other crucial proteins to regulate wing-specific genes.

The Notch and Wingless signaling pathways activate vestigial in the early stages of wing development using a boundary enhancer.

In the later stages, Wingless and Dpp (Decapentaplegic) signaling pathways turn on vestigial, resulting in its expression throughout the entire wing disc.

These are pockets of cells in the larva that remain dormant and develop during metamorphosis into adult structures like wings, legs, and antennae. They essentially provide the blueprint for the organism's adult features.

Drosophila leg imaginal discs are patterned similarly to the wing disc, with the leg disc resembling a collapsed cone. They are comprised of epidermal cells that join together to form the leg's segments.

The A-P (anterior-posterior) axis of the leg disc is patterned by the expression of various signaling molecules, including Hedgehog (Hh), Engrailed (En), and Ap (apterous), which are expressed in specific regions, directing the fate of the cells.

The D-V axis of the leg is established by the expression of two crucial signals - Wingless (Wg) on the ventral side and Dpp on the dorsal side. These interactions help define the distinct regions of the leg.

These are small outgrowths that emerge from the body wall of the embryo, giving rise to the adult limbs. They are comprised of two main components: a mesenchymal core and an outer epithelial layer.